Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 98198..98810 Replicon plasmid pTPRO2
Accession NZ_CP014798
Organism Salipiger profundus strain JLT2016

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Ga0080559_RS23635 Protein ID WP_028288627.1
Coordinates 98198..98593 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A921TG38
Locus tag Ga0080559_RS23640 Protein ID WP_009503866.1
Coordinates 98583..98810 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ga0080559_RS23600 93740..93970 - 231 WP_050759304.1 mercury resistance system transport protein MerF -
Ga0080559_RS23605 94068..94370 - 303 WP_008335977.1 hypothetical protein -
Ga0080559_RS23610 94387..94692 - 306 WP_009807473.1 hypothetical protein -
Ga0080559_RS23615 94705..95112 - 408 WP_176244179.1 mercury transporter -
Ga0080559_RS23620 95209..95610 + 402 WP_008335980.1 helix-turn-helix domain-containing protein -
Ga0080559_RS23625 95940..97007 - 1068 WP_008335981.1 hypothetical protein -
Ga0080559_RS23630 97235..98119 + 885 WP_028288628.1 recombinase family protein -
Ga0080559_RS23635 98198..98593 - 396 WP_028288627.1 PIN domain-containing protein Toxin
Ga0080559_RS23640 98583..98810 - 228 WP_009503866.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
Ga0080559_RS23645 99019..100212 + 1194 WP_009503867.1 plasmid partitioning protein RepA -
Ga0080559_RS23650 100196..101128 + 933 WP_028288626.1 plasmid partitioning protein RepB -
Ga0080559_RS23655 101342..102553 + 1212 WP_076625738.1 replication initiation protein RepC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..126548 126548


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-113)

Antitoxin

Antitoxin PemI-like

(2-47)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14212.23 Da        Isoelectric Point: 4.1653

>T61821 WP_028288627.1 NZ_CP014798:c98593-98198 [Salipiger profundus]
MSVEFADTNVVLYLLDDGPKADRAEVILGQGPRISVQVLNESLVNCRRKAGLGWEEAAAFLEGVRALCPVEDLTVQTHDV
GRALAERYGFSIYDAMIVASALVAGCTTLWSEDMQDGLLVEGQLRIVNPFA

Download         Length: 396 bp

>T61821 NZ_CP014798:c98593-98198 [Salipiger profundus]
ATGAGCGTTGAGTTCGCGGACACGAATGTCGTTCTTTACCTGCTCGACGACGGCCCAAAGGCCGATCGCGCCGAGGTCAT
CCTGGGGCAGGGGCCCCGGATCAGCGTTCAGGTTCTAAACGAGTCACTGGTGAACTGCCGCCGCAAAGCTGGCCTCGGTT
GGGAGGAAGCAGCGGCCTTTCTCGAAGGCGTGCGCGCCTTGTGTCCCGTCGAAGATCTCACCGTGCAGACCCATGACGTC
GGCCGCGCTTTGGCGGAACGCTACGGCTTCTCGATCTACGACGCGATGATCGTGGCCAGCGCTTTGGTTGCGGGGTGTAC
CACGCTGTGGAGCGAGGACATGCAAGATGGCCTGCTGGTGGAAGGCCAGCTTCGCATCGTCAACCCCTTTGCATGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8535.79 Da        Isoelectric Point: 11.0482

>AT61821 WP_009503866.1 NZ_CP014798:c98810-98583 [Salipiger profundus]
MQVAKWGNSLAVRLPAELVRELGLKEGDQIDLVKDDGRVRVRRLARADEVLTGLRRFRGKLSAAERLSRDDAHER

Download         Length: 228 bp

>AT61821 NZ_CP014798:c98810-98583 [Salipiger profundus]
ATGCAGGTCGCAAAATGGGGTAACTCGCTGGCCGTCCGTTTGCCCGCGGAGCTCGTCCGAGAGCTTGGTCTCAAGGAGGG
TGATCAGATCGACCTGGTCAAGGACGACGGTCGGGTCAGAGTCCGTCGCCTTGCTCGTGCGGATGAGGTACTTACCGGCC
TGCGCCGCTTCCGGGGCAAGTTGTCCGCAGCAGAACGTCTGAGCCGCGACGACGCACATGAGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References