Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3228757..3229403 Replicon chromosome
Accession NZ_CP014796
Organism Salipiger profundus strain JLT2016

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Ga0080559_RS15675 Protein ID WP_076624292.1
Coordinates 3228996..3229403 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Ga0080559_RS15670 Protein ID WP_076624291.1
Coordinates 3228757..3228999 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Ga0080559_RS15650 3224794..3225675 + 882 WP_076624288.1 ABC transporter permease subunit -
Ga0080559_RS15655 3225686..3226606 + 921 WP_083697841.1 ABC transporter permease subunit -
Ga0080559_RS15660 3226651..3227694 + 1044 WP_076624289.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
Ga0080559_RS15665 3227691..3228737 + 1047 WP_076624290.1 endonuclease/exonuclease/phosphatase family protein -
Ga0080559_RS15670 3228757..3228999 + 243 WP_076624291.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Ga0080559_RS15675 3228996..3229403 + 408 WP_076624292.1 type II toxin-antitoxin system VapC family toxin Toxin
Ga0080559_RS15680 3229415..3229819 - 405 WP_076624293.1 response regulator -
Ga0080559_RS15685 3229797..3233249 - 3453 WP_076624294.1 PAS domain-containing protein -
Ga0080559_RS15690 3233268..3233813 - 546 WP_017467367.1 PAS domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-119)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-48)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15134.28 Da        Isoelectric Point: 5.7614

>T61820 WP_076624292.1 NZ_CP014796:3228996-3229403 [Salipiger profundus]
MIYILDTNVISDARRAHRAPQVAQWLADRDERELYLSVVTLGEIERGIVLQERKNPEFARDLRAWLARTVQLFSDRLLPF
TTEDALRWGALSARVGHPGADLMIAAQALTRDAAVVTRNVADFEPTGARIVDPLA

Download         Length: 408 bp

>T61820 NZ_CP014796:3228996-3229403 [Salipiger profundus]
TTGATCTACATCCTCGACACCAACGTGATCTCGGATGCCCGCCGGGCCCATCGCGCGCCGCAGGTGGCGCAATGGCTGGC
GGATCGTGACGAGCGCGAGCTTTACCTGAGCGTCGTCACGCTGGGCGAGATCGAGCGTGGCATCGTGCTTCAGGAGCGGA
AGAACCCGGAGTTCGCGCGCGATCTGCGGGCGTGGCTGGCGCGCACGGTCCAGCTGTTCTCGGATCGTCTGCTGCCGTTC
ACGACCGAGGATGCACTGCGCTGGGGCGCGCTGTCGGCGCGGGTGGGACACCCGGGCGCCGACCTGATGATCGCGGCGCA
GGCGCTGACGCGCGATGCGGCCGTGGTGACCCGGAATGTCGCGGATTTCGAACCGACGGGGGCGCGGATCGTCGACCCGC
TTGCCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8787.08 Da        Isoelectric Point: 10.4482

>AT61820 WP_076624291.1 NZ_CP014796:3228757-3228999 [Salipiger profundus]
MLSLQDAKNRFSAVVEAALAGRPQKVSRRGKPAVVVLAAEEYERLVKAAQTQRGSFQEHLMALPADDVPRAAARPRDVEF

Download         Length: 243 bp

>AT61820 NZ_CP014796:3228757-3228999 [Salipiger profundus]
ATGCTTTCGCTTCAGGATGCCAAGAACCGCTTCAGTGCCGTCGTCGAGGCGGCGCTTGCCGGACGCCCGCAAAAGGTCTC
GCGCCGGGGCAAACCCGCCGTGGTGGTTCTGGCCGCCGAGGAATACGAGCGCCTGGTGAAGGCCGCGCAGACCCAGCGCG
GCAGTTTCCAGGAGCATCTCATGGCGCTTCCCGCCGACGACGTGCCGCGCGCGGCGGCACGTCCGCGAGACGTGGAGTTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References