Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 903838..904757 Replicon chromosome
Accession NZ_CP014794
Organism Bacillus licheniformis strain SCCB 37

Toxin (Protein)


Gene name spoIISA Uniprot ID T5HIF3
Locus tag B37_RS04855 Protein ID WP_003180879.1
Coordinates 904011..904757 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID T5HT37
Locus tag B37_RS04850 Protein ID WP_003180877.1
Coordinates 903838..904011 (-) Length 58 a.a.

Genomic Context

B37_RS04830B37_RS04835B37_RS04840B37_RS04845B37_RS04870B37_RS04875B37_RS04850B37_RS04855B37_RS04860B37_RS04865
Location: 899263..900360 (1098 bp)
Type: Others
Protein ID: WP_003180867.1
Location: 900336..901184 (849 bp)
Type: Others
Protein ID: WP_003180869.1
Location: 901211..902224 (1014 bp)
Type: Others
Protein ID: WP_011197810.1
Location: 902277..903548 (1272 bp)
Type: Others
Protein ID: WP_009328725.1
Location: 906828..908585 (1758 bp)
Type: Others
Protein ID: WP_011197813.1
Location: 908714..909357 (644 bp)
Type: Others
Protein ID: Protein_942
Location: 903838..904011 (174 bp)
Type: Antitoxin
Protein ID: WP_003180877.1
Location: 904011..904757 (747 bp)
Type: Toxin
Protein ID: WP_003180879.1
Location: 904868..905866 (999 bp)
Type: Others
Protein ID: WP_009328723.1
Location: 905879..906496 (618 bp)
Type: Others
Protein ID: WP_003180884.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B37_RS04830899263..900360+1098WP_003180867.1mannonate dehydratase-
B37_RS04835900336..901184+849WP_003180869.1SDR family oxidoreductase-
B37_RS04840901211..902224+1014WP_011197810.1zinc-binding alcohol dehydrogenase family protein-
B37_RS04845902277..903548+1272WP_009328725.1MFS transporter-
B37_RS04850903838..904011-174WP_003180877.1type II toxin-antitoxin system SpoIISB family antitoxinAntitoxin
B37_RS04855904011..904757-747WP_003180879.1type II toxin-antitoxin system SpoIISA family toxinToxin
B37_RS04860904868..905866-999WP_009328723.1inorganic phosphate transporter-
B37_RS04865905879..906496-618WP_003180884.1DUF47 domain-containing protein-
B37_RS04870906828..908585+1758WP_011197813.1gamma-glutamyltransferase-
B37_RS04875908714..909357+644Protein_942DUF624 domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29391.80 Da        Isoelectric Point: 4.5367

>T61816 WP_003180879.1 NZ_CP014794:c904757-904011 [Bacillus licheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKQLAEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLDRKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD

Download         Length: 747 bp

>T61816 NZ_CP014794:c904757-904011 [Bacillus licheniformis]
ATGCTGCTATTTTATCAATTCCTTGTTTGGCTTATTGTTTTGGCGCTGGCTCTGTACGTAGCTGCCGTGTGGCGTTTTGA
AAAACAGCTCGCCGAAAAAACGGTCGCCATCAGAAAAACGTGGTACCTTCTTTATGTCATCGGCGCCGTGATATATTGGA
CGCACGATCCGCAGTCAATTTTCACAAACCCGCTTCATTACCTGATCGTTGCCGTTTTTTTCACGTTGACAGACGCTTTT
ATTTTCTTAAATGCCTACTTTAAAAAGCTCGGCAGCTCTGAACTCGCGACAGATACAAGAATGCTTCTCGAAGAAAACAA
CGACCTCCTCCACACGTATCAAAACAGGCTGAAAACGTTTCAATACCTATTGAAAAACGAACCGATCCACATCTATTATG
GAAATATAGAAGCGTATGCAGAAGGCATCGAAAAGCTCATCAAACGGTTTGCCGAAAAAATGAATATATCCGCTGCACTT
TGCGAATATAATTCAGAAGAAAGCAAGGATCATTTGCTTGAGCATATGGAAAACCGGTTCGATGTTCAAGAAAAGCTTGA
CCGCAAAGACGTTTATTATGAAGAAAACGGAAAAATGGTCCTCATTCCTTTTTCCATCCACGATTTTGACTATGTCATGA
AGTTAACCTCAGAAGACCTTGTCACAGAATTTGATTATCTCCTGTTTACTTCTTTAACAAGCATCTATGATCTTCTGCTA
CCAAACGAAGAGGAAGGTGACGACTGA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6945.04 Da        Isoelectric Point: 10.9186

>AT61816 WP_003180877.1 NZ_CP014794:c904011-903838 [Bacillus licheniformis]
MEPAFQQDQESVKKRLAFKMFKRQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp

>AT61816 NZ_CP014794:c904011-903838 [Bacillus licheniformis]
ATGGAGCCTGCTTTTCAGCAAGACCAGGAAAGCGTAAAAAAGCGCCTCGCCTTTAAAATGTTTAAAAGGCAATCCAAAAC
CAATATCGCGAAATACGAAGTCAGCCCCCATACCGAACGGATTTTCCGGCAAAACGAACGGCTGATCGGCGAGTATAAAA
GAAAAAAAGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBT5HIF3

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBT5HT37

References