Detailed information of TA system TA061801

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5312604..5313120
• Replicon: chromosome
• Accession: NZ_CP014782
• Organism: Shewanella psychrophila strain WP2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: sps_RS23115
• Protein ID: WP_077754626.1
• Coordinates: 5312836..5313120 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: sps_RS23110
• Protein ID: WP_077754625.1
• Coordinates: 5312604..5312846 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
sps_RS23090	5308854..5309177	+	324	WP_077754621.1	hypothetical protein	-
sps_RS23095	5309203..5309664	+	462	WP_179948385.1	hypothetical protein	-
sps_RS23100	5309783..5310094	+	312	WP_077754622.1	hypothetical protein	-
sps_RS23105	5310635..5312329	+	1695	WP_169915885.1	ATP-binding protein	-
sps_RS23110	5312604..5312846	+	243	WP_077754625.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
sps_RS23115	5312836..5313120	+	285	WP_077754626.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
sps_RS23120	5313575..5314123	+	549	WP_077754628.1	DUF2913 family protein	-
sps_RS23125	5314639..5314830	-	192	WP_077754630.1	hypothetical protein	-
sps_RS23135	5315643..5316785	+	1143	WP_077751384.1	IS4 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	5289055..5347102	58047
	-	flank	IS/Tn	-	-	5315643..5316785	1142

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-68)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11235.23 Da
• Isoelectric Point: 10.5384

>T61801 WP_077754626.1 NZ_CP014782:5312836-5313120 [Shewanella psychrophila]
MIYELEFDPRALKEWRKLGNTVRKQFKNKLTEVLKHPHIEANRLRELPCCYKIKLRSAGYRLIYQVQDEKVTVFVIAVGK
RESDRVYKVANKRA

Nucleotide

• Length: 285 bp

>T61801 NZ_CP014782:5312836-5313120 [Shewanella psychrophila]
ATGATTTATGAATTAGAGTTTGATCCTCGTGCCCTGAAAGAGTGGCGAAAACTAGGTAATACGGTTCGCAAGCAGTTTAA
GAATAAGCTAACGGAAGTTTTAAAGCATCCGCACATAGAGGCTAATCGTTTAAGAGAGCTACCCTGCTGTTATAAAATTA
AACTGCGTAGTGCTGGATATCGATTAATCTACCAGGTTCAAGATGAAAAGGTCACCGTGTTTGTTATTGCTGTTGGTAAA
AGAGAAAGTGATCGCGTTTATAAAGTAGCAAACAAGCGGGCTTAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8705.11 Da
• Isoelectric Point: 4.7247

>AT61801 WP_077754625.1 NZ_CP014782:5312604-5312846 [Shewanella psychrophila]
MGTINIRVDDGLKARSYAALEKLGVTPSELLRQTLEYVAQRGTLPFKPVLLTDEDEALISLAKARLAEPLPGVKVSLDDL

Nucleotide

• Length: 243 bp

>AT61801 NZ_CP014782:5312604-5312846 [Shewanella psychrophila]
ATGGGAACAATTAATATTAGGGTTGATGATGGACTTAAAGCTCGTTCTTATGCTGCTTTAGAGAAACTGGGTGTCACGCC
TTCTGAATTGTTACGTCAAACACTTGAGTATGTTGCTCAAAGAGGGACGCTCCCTTTTAAGCCTGTACTGTTAACTGATG
AGGATGAAGCGTTGATCTCATTAGCTAAAGCTCGACTTGCAGAACCCTTACCTGGTGTAAAGGTTTCTTTGGATGATTTA
TGA