Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3457551..3457696 Replicon chromosome
Accession NZ_CP014762
Organism Klebsiella pneumoniae strain KPNIH39

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3457558..3457660 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3457551..3457696 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WM47_RS17380 3453432..3453671 + 240 WP_002911393.1 YebV family protein -
WM47_RS17385 3453769..3453960 + 192 WP_002911395.1 YebW family protein -
WM47_RS17390 3453957..3454610 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
WM47_RS17395 3454767..3455735 + 969 WP_004151446.1 VirK/YbjX family protein -
WM47_RS31305 3455840..3455983 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
WM47_RS17405 3456183..3457163 + 981 WP_009310076.1 IS5-like element ISKpn26 family transposase -
- 3457551..3457696 + 146 - - Antitoxin
- 3457558..3457660 - 103 - - Toxin
WM47_RS17410 3457819..3458157 - 339 WP_002911404.1 YebY family protein -
WM47_RS17415 3458174..3459043 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
WM47_RS17420 3459047..3459421 - 375 WP_004151448.1 CopC domain-containing protein YobA -
WM47_RS17425 3459534..3459764 + 231 WP_064798405.1 DNA polymerase III subunit theta -
WM47_RS17430 3459843..3460502 + 660 WP_002911407.1 exodeoxyribonuclease X -
WM47_RS17435 3460506..3462566 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3456183..3457163 980


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T61776 NZ_CP014762:c3457660-3457558 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT61776 NZ_CP014762:3457551-3457696 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References