Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3796394..3796904 Replicon chromosome
Accession NZ_CP014754
Organism Marinobacter sp. LQ44

Toxin (Protein)


Gene name - Uniprot ID A0A142FV29
Locus tag ASQ50_RS17465 Protein ID WP_058092344.1
Coordinates 3796641..3796904 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A142FV28
Locus tag ASQ50_RS17460 Protein ID WP_058092345.1
Coordinates 3796394..3796651 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASQ50_RS17445 3792252..3793529 + 1278 WP_058092347.1 MFS transporter -
ASQ50_RS20685 3793880..3795631 + 1752 WP_156510033.1 type VI secretion system PAAR protein -
ASQ50_RS17455 3795621..3796211 + 591 WP_058092346.1 DUF2931 family protein -
ASQ50_RS17460 3796394..3796651 - 258 WP_058092345.1 hypothetical protein Antitoxin
ASQ50_RS17465 3796641..3796904 - 264 WP_058092344.1 BrnT family toxin Toxin
ASQ50_RS17470 3797037..3797522 - 486 WP_058092343.1 shikimate kinase -
ASQ50_RS17480 3797887..3799049 + 1163 Protein_3460 IS3 family transposase -
ASQ50_RS17485 3799218..3800543 + 1326 WP_068351393.1 IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3790774..3800543 9769


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10311.76 Da        Isoelectric Point: 8.4938

>T61742 WP_058092344.1 NZ_CP014754:c3796904-3796641 [Marinobacter sp. LQ44]
MGEFEFDEAKSQANLDKHGIDFVAAQRLWKDPYLLEIRAKSEDEQRFLLIGKIGEKHWSAVVTYRDARIRLISVRRSRKK
EVELYES

Download         Length: 264 bp

>T61742 NZ_CP014754:c3796904-3796641 [Marinobacter sp. LQ44]
ATGGGTGAATTTGAATTCGACGAAGCAAAAAGCCAGGCCAATCTGGATAAGCACGGTATTGATTTCGTTGCTGCACAGAG
GCTGTGGAAAGATCCATACCTGCTGGAGATCCGCGCAAAATCAGAGGATGAGCAGCGGTTTTTGCTAATCGGCAAGATTG
GTGAAAAGCACTGGTCGGCTGTCGTCACATACAGGGATGCTCGTATTCGTCTGATTTCAGTCAGGCGTTCCCGCAAGAAG
GAGGTTGAGCTCTATGAAAGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9938.17 Da        Isoelectric Point: 5.8992

>AT61742 WP_058092345.1 NZ_CP014754:c3796651-3796394 [Marinobacter sp. LQ44]
MKAKDFDKKFEEGQEDIIDDLDLSSARRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANTHE
PSRKR

Download         Length: 258 bp

>AT61742 NZ_CP014754:c3796651-3796394 [Marinobacter sp. LQ44]
ATGAAAGCTAAAGACTTCGACAAAAAATTTGAGGAAGGTCAGGAAGATATTATTGATGATCTGGACCTGTCCTCTGCTCG
CCGCGTTAATCAGGAACAAAAGCGAATCAACGTCGATTTCCCGGCTTGGGTTGTCGAGTCTTTGGATCGTGAGGCTGCGC
GCATTGGCGTTACCCGCCAATCAATCATCAAAGTGTGGCTGGTGGAGCGCCTTCAGGCAGAATCTGCTAACACACATGAG
CCTTCTCGGAAACGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A142FV29

Antitoxin

Source ID Structure
AlphaFold DB A0A142FV28

References