Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3773159..3773694 Replicon chromosome
Accession NZ_CP014754
Organism Marinobacter sp. LQ44

Toxin (Protein)


Gene name parE Uniprot ID A0A142FV05
Locus tag ASQ50_RS17340 Protein ID WP_058091654.1
Coordinates 3773159..3773455 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A137S2R8
Locus tag ASQ50_RS17345 Protein ID WP_058091653.1
Coordinates 3773455..3773694 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASQ50_RS17315 3768410..3769189 + 780 WP_058091659.1 enoyl-CoA hydratase -
ASQ50_RS17320 3769204..3770289 + 1086 WP_058091658.1 enoyl-CoA hydratase/isomerase family protein -
ASQ50_RS17325 3770332..3771219 + 888 WP_058091657.1 3-hydroxyisobutyrate dehydrogenase -
ASQ50_RS17330 3771258..3771992 - 735 WP_058091656.1 acyltransferase family protein -
ASQ50_RS17335 3772000..3772704 - 705 WP_058091655.1 SGNH/GDSL hydrolase family protein -
ASQ50_RS17340 3773159..3773455 - 297 WP_058091654.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ASQ50_RS17345 3773455..3773694 - 240 WP_058091653.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ASQ50_RS17350 3773808..3774482 + 675 WP_058091652.1 hypothetical protein -
ASQ50_RS17355 3774942..3775697 - 756 WP_058091651.1 SDR family oxidoreductase -
ASQ50_RS17360 3775834..3776748 + 915 WP_058091650.1 LysR family transcriptional regulator -
ASQ50_RS17365 3776910..3778211 - 1302 WP_068351333.1 IS1380 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3776910..3778211 1301


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(4-71)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11505.36 Da        Isoelectric Point: 9.7458

>T61741 WP_058091654.1 NZ_CP014754:c3773455-3773159 [Marinobacter sp. LQ44]
MLNFKLSRKAKADLKSIALYTERKWGRDKRNHYILQFDQCFQLLGENPNLGQTCDGIRADYLQYPQGSHIIFYRVATDSV
VEIIRILHKRMLPDGHLL

Download         Length: 297 bp

>T61741 NZ_CP014754:c3773455-3773159 [Marinobacter sp. LQ44]
ATGCTGAATTTCAAGCTTTCCAGGAAGGCCAAAGCTGATCTCAAATCTATTGCACTGTACACGGAGCGTAAATGGGGCCG
AGATAAACGAAACCACTACATTCTCCAGTTTGACCAGTGCTTCCAACTACTGGGCGAAAACCCGAATCTGGGGCAAACCT
GCGATGGGATCCGCGCGGACTACCTACAGTATCCCCAAGGAAGTCACATCATATTCTATCGGGTAGCGACCGACAGTGTC
GTTGAGATTATCCGTATTCTACACAAACGCATGTTGCCAGATGGGCATCTCCTTTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9151.10 Da        Isoelectric Point: 4.5332

>AT61741 WP_058091653.1 NZ_CP014754:c3773694-3773455 [Marinobacter sp. LQ44]
MQKNTSITLGQHFDAFIAEQLKTGRYSSTSEVVRAGLRLLEESETRLTTLRKLLKEGEDSGFEDYSYDSFIRELDNEER

Download         Length: 240 bp

>AT61741 NZ_CP014754:c3773694-3773455 [Marinobacter sp. LQ44]
ATGCAAAAGAACACCAGCATCACTCTAGGCCAACATTTTGATGCGTTCATTGCGGAACAACTCAAAACTGGCCGATACAG
CTCAACCAGCGAAGTTGTTCGTGCAGGATTGCGCCTGCTTGAAGAGTCCGAAACCCGCCTGACTACGCTCCGCAAACTTC
TTAAGGAAGGCGAAGATAGTGGCTTTGAAGACTACTCTTATGACTCTTTCATTCGCGAACTGGACAACGAAGAGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A142FV05

Antitoxin

Source ID Structure
AlphaFold DB A0A137S2R8

References