Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 659825..660327 Replicon chromosome
Accession NZ_CP014754
Organism Marinobacter sp. LQ44

Toxin (Protein)


Gene name yoeB Uniprot ID A0A142FMP5
Locus tag ASQ50_RS03135 Protein ID WP_058092925.1
Coordinates 660073..660327 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A142FMP4
Locus tag ASQ50_RS03130 Protein ID WP_058092924.1
Coordinates 659825..660076 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASQ50_RS03090 655565..655828 - 264 WP_058092927.1 Txe/YoeB family addiction module toxin -
ASQ50_RS03095 655825..656067 - 243 WP_058092928.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
ASQ50_RS03100 656219..656653 - 435 WP_058092929.1 hypothetical protein -
ASQ50_RS03105 656823..657110 - 288 WP_058092930.1 hypothetical protein -
ASQ50_RS03110 657231..658256 + 1026 WP_068351341.1 IS110 family transposase -
ASQ50_RS03115 658648..658881 - 234 WP_058092921.1 hypothetical protein -
ASQ50_RS03130 659825..660076 + 252 WP_058092924.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ASQ50_RS03135 660073..660327 + 255 WP_058092925.1 Txe/YoeB family addiction module toxin Toxin
ASQ50_RS03145 661007..661762 - 756 WP_058092926.1 IS21-like element ISSpu5 family helper ATPase IstB -
ASQ50_RS03150 661774..662682 - 909 Protein_613 IS21 family transposase -
ASQ50_RS03155 662770..663786 - 1017 WP_058092803.1 tyrosine-type recombinase/integrase -
ASQ50_RS03160 663783..664772 - 990 WP_058092802.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 649475..660662 11187
- inside Integron - - 656219..660758 4539


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10222.75 Da        Isoelectric Point: 9.6072

>T61738 WP_058092925.1 NZ_CP014754:660073-660327 [Marinobacter sp. LQ44]
MKLIFSENAWEDYLYWQKTDKKILNRINKLINETKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLIAQL
RYHY

Download         Length: 255 bp

>T61738 NZ_CP014754:660073-660327 [Marinobacter sp. LQ44]
ATGAAACTCATCTTCTCCGAGAACGCCTGGGAAGACTATCTGTACTGGCAGAAAACCGACAAAAAGATTCTTAACCGAAT
CAACAAGCTGATCAATGAGACCAAACGAGAACCGTTCGAAGGTGTTGGCAAACCAGAGCCCCTCAAACACAGCCTCGCCG
GGTACTGGTCTCGCCGGATCAACGAAGAACACCGAATAGTTTACAAAGTCACGGATGACGCTTTGCTTATCGCCCAGCTC
CGGTATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9285.50 Da        Isoelectric Point: 4.4750

>AT61738 WP_058092924.1 NZ_CP014754:659825-660076 [Marinobacter sp. LQ44]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRSKSQSVVMISLEDYEALQETAYLLRSPKNARRLLESVAELEQGGGQEKE
LLE

Download         Length: 252 bp

>AT61738 NZ_CP014754:659825-660076 [Marinobacter sp. LQ44]
ATGGATGCCATTAGCTACACAGCCGCTAGAACCAATCTAGCAAAAACCATGGAGCAGGTCTGTGAAGACCATTCCCCTGT
GATCATCACCCGGAGCAAGTCGCAGTCCGTGGTAATGATCTCCCTAGAGGACTACGAGGCGCTGCAAGAGACTGCATACC
TTCTGCGCTCACCAAAAAACGCACGGCGTTTGCTGGAATCCGTTGCCGAGCTGGAGCAAGGCGGTGGTCAAGAAAAGGAA
CTTCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A142FMP5

Antitoxin

Source ID Structure
AlphaFold DB A0A142FMP4

References