Detailed information of TA system TA061737

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-YefM
• Location: 652871..653373
• Replicon: chromosome
• Accession: NZ_CP014754
• Organism: Marinobacter sp. LQ44

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: M7CQI7
• Locus tag: ASQ50_RS03070
• Protein ID: WP_008938367.1
• Coordinates: 653119..653373 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A142FMP4
• Locus tag: ASQ50_RS03065
• Protein ID: WP_058092924.1
• Coordinates: 652871..653122 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ASQ50_RS03030	649133..649345	-	213	WP_156509971.1	hypothetical protein	-
ASQ50_RS03035	649475..650434	-	960	WP_058090522.1	calcium/sodium antiporter	-
ASQ50_RS20360	650817..651061	+	245	Protein_595	type II toxin-antitoxin system CcdA family antitoxin	-
ASQ50_RS03040	651061..651378	+	318	WP_058090521.1	CcdB family protein	-
ASQ50_RS03045	651445..651747	-	303	WP_058090520.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ASQ50_RS03050	651735..651992	-	258	WP_058090519.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ASQ50_RS03055	652178..652489	+	312	WP_058090518.1	BrnT family toxin	-
ASQ50_RS03060	652464..652736	+	273	WP_027830482.1	BrnA antitoxin family protein	-
ASQ50_RS03065	652871..653122	+	252	WP_058092924.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ASQ50_RS03070	653119..653373	+	255	WP_008938367.1	Txe/YoeB family addiction module toxin	Toxin
ASQ50_RS03085	654203..655228	+	1026	WP_068351341.1	IS110 family transposase	-
ASQ50_RS03090	655565..655828	-	264	WP_058092927.1	Txe/YoeB family addiction module toxin	-
ASQ50_RS03095	655825..656067	-	243	WP_058092928.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ASQ50_RS03100	656219..656653	-	435	WP_058092929.1	hypothetical protein	-
ASQ50_RS03105	656823..657110	-	288	WP_058092930.1	hypothetical protein	-
ASQ50_RS03110	657231..658256	+	1026	WP_068351341.1	IS110 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	649475..660662	11187
	-	inside	Integron	-	-	656219..660758	4539

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10236.82 Da
• Isoelectric Point: 9.8162

>T61737 WP_008938367.1 NZ_CP014754:653119-653373 [Marinobacter sp. LQ44]
MKLIFSENAWEDYLYWQKTDKKILNRINKLIKETKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLIAQL
RYHY

Nucleotide

• Length: 255 bp

>T61737 NZ_CP014754:653119-653373 [Marinobacter sp. LQ44]
ATGAAACTCATCTTCTCCGAGAACGCCTGGGAAGACTATCTGTACTGGCAGAAAACCGACAAAAAGATTCTTAACCGAAT
CAACAAACTGATCAAAGAGACCAAACGAGAACCGTTCGAAGGTGTTGGCAAACCAGAGCCCCTCAAACACAGCCTCGCCG
GGTACTGGTCCCGCCGGATCAACGAAGAACACCGAATAGTTTACAAAGTCACGGATGACGCTTTGCTTATCGCCCAGCTC
CGGTATCACTACTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9285.50 Da
• Isoelectric Point: 4.4750

>AT61737 WP_058092924.1 NZ_CP014754:652871-653122 [Marinobacter sp. LQ44]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRSKSQSVVMISLEDYEALQETAYLLRSPKNARRLLESVAELEQGGGQEKE
LLE

Nucleotide

• Length: 252 bp

>AT61737 NZ_CP014754:652871-653122 [Marinobacter sp. LQ44]
ATGGATGCCATTAGCTACACAGCCGCTAGAACCAATCTAGCAAAAACCATGGAGCAGGTCTGTGAAGACCATTCCCCTGT
GATCATCACCCGGAGCAAGTCGCAGTCCGTGGTAATGATCTCCCTAGAGGACTACGAGGCGCTGCAAGAGACTGCATACC
TTCTGCGCTCACCAAAAAACGCACGGCGTTTGCTGGAATCCGTTGCCGAGCTGGAGCAAGGCGGTGGTCAAGAAAAGGAA
CTTCTTGAATGA

Structures

Toxin

• AlphaFold DB: M7CQI7

Antitoxin

• AlphaFold DB: A0A142FMP4