Detailed information of TA system TA061735

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 418429..419585
• Replicon: chromosome
• Accession: NZ_CP014754
• Organism: Marinobacter sp. LQ44

Toxin (Protein)

• Gene name: -
• Uniprot ID: A0A142FM38
• Locus tag: ASQ50_RS01970
• Protein ID: WP_058091067.1
• Coordinates: 418791..419585 (+)
• Length: 265 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A142FM37
• Locus tag: ASQ50_RS01965
• Protein ID: WP_058091066.1
• Coordinates: 418429..418794 (+)
• Length: 122 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ASQ50_RS01950	413588..415192	+	1605	WP_058091063.1	FAD-binding oxidoreductase	-
ASQ50_RS01955	415200..416786	+	1587	WP_058091064.1	glycerol-3-phosphate dehydrogenase/oxidase	-
ASQ50_RS01960	416792..418351	+	1560	WP_058091065.1	FGGY-family carbohydrate kinase	-
ASQ50_RS01965	418429..418794	+	366	WP_058091066.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
ASQ50_RS01970	418791..419585	+	795	WP_058091067.1	RES family NAD+ phosphorylase	Toxin
ASQ50_RS01975	419563..420975	-	1413	WP_058091078.1	efflux transporter outer membrane subunit	-
ASQ50_RS01980	420986..422926	-	1941	WP_058091068.1	MacB family efflux pump subunit	-
ASQ50_RS01985	422923..424074	-	1152	WP_058091069.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (60-219)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (9-66)

Sequences

Toxin

Protein

• Length: 265 a.a.
• Molecular weight: 29639.60 Da
• Isoelectric Point: 8.7449

>T61735 WP_058091067.1 NZ_CP014754:418791-419585 [Marinobacter sp. LQ44]
MNYRERIKNTLGSPQGQLFRVVESQEDIATTQIVDNMQEQARLEQLLDASKPTIPEQANKLHYLLATPFRYPPLKYGSRF
GRSFEPSLFYGAMSIPTALAETAFYRFVFTSHVSEPFKRPLTTLHTVFTARFRSSRGGRLQATEWQDLQEILTDPVSYRE
SQALGSDLRQCGAEAFQFLSARALQAGLYQLPWQTGSGMDGLNVALFSPRALRDTAPRSYHKLIVATSDQQVSMSLTLAD
GSKQVHNFGREAFLVEGVIPQPAL

Nucleotide

• Length: 795 bp

>T61735 NZ_CP014754:418791-419585 [Marinobacter sp. LQ44]
TTGAACTACAGGGAACGTATTAAAAACACCCTGGGCAGCCCACAGGGCCAGCTCTTTCGGGTAGTAGAGAGTCAGGAAGA
CATCGCCACCACCCAAATCGTTGATAACATGCAGGAACAGGCTCGCCTGGAGCAACTGCTCGATGCCAGCAAACCGACGA
TCCCCGAGCAGGCCAACAAGCTGCATTACCTGCTGGCGACGCCCTTTCGATACCCGCCACTCAAATACGGCTCTCGGTTC
GGCCGCAGCTTTGAGCCCAGCCTGTTCTACGGCGCCATGAGCATTCCGACAGCCCTGGCAGAAACCGCTTTTTACCGGTT
TGTGTTCACCAGCCACGTGTCAGAACCGTTCAAGCGCCCTTTGACCACCCTGCACACGGTCTTTACCGCCCGCTTCCGTT
CAAGTCGGGGGGGTCGGCTTCAGGCCACAGAGTGGCAAGATCTTCAGGAAATCCTCACTGATCCGGTCAGCTACCGGGAA
TCCCAGGCGCTGGGCAGCGACCTGCGCCAGTGCGGCGCGGAAGCGTTTCAATTTCTCTCGGCCCGGGCTCTGCAGGCCGG
TTTGTACCAGCTACCCTGGCAAACCGGAAGCGGAATGGATGGACTCAACGTGGCGCTGTTCAGCCCCCGCGCTCTGCGAG
ACACGGCGCCAAGGTCGTACCACAAACTCATCGTTGCCACCTCAGACCAACAAGTATCCATGAGTCTGACTCTGGCGGAT
GGCAGCAAGCAGGTTCACAACTTCGGCCGGGAAGCTTTTCTGGTAGAGGGCGTTATTCCTCAACCGGCCCTGTAG

Antitoxin

Protein

• Length: 122 a.a.
• Molecular weight: 13131.92 Da
• Isoelectric Point: 8.5040

>AT61735 WP_058091066.1 NZ_CP014754:418429-418794 [Marinobacter sp. LQ44]
MNEPATLAAQTSDKALLAKALLNSAKAFGLSQAEAAAIVGRNRSGLTRDGIDPDSKSGELALLFVRLYRSVYALTGGDNQ
AMAHWLNTPNHYFEGTPRDMIQSTEGLVRVIHYLDAMRGRI

Nucleotide

• Length: 366 bp

>AT61735 NZ_CP014754:418429-418794 [Marinobacter sp. LQ44]
ATGAACGAGCCGGCTACCCTGGCCGCCCAAACCAGCGACAAAGCCCTGCTGGCCAAAGCCTTGCTGAATTCCGCCAAGGC
TTTTGGTCTTTCCCAGGCCGAAGCCGCCGCCATTGTTGGCCGAAATCGCAGCGGTTTGACCCGAGACGGCATTGATCCGG
ACAGTAAGTCCGGAGAACTGGCGCTGCTGTTCGTGCGCCTGTATCGGAGCGTTTATGCCCTCACCGGTGGCGACAACCAG
GCCATGGCCCACTGGCTCAACACGCCAAACCACTACTTTGAAGGCACCCCCAGGGATATGATTCAGTCAACGGAGGGGCT
GGTTCGGGTGATTCACTATCTGGATGCCATGCGGGGAAGGATTTGA

Structures

Toxin

• AlphaFold DB: A0A142FM38

Antitoxin

• AlphaFold DB: A0A142FM37