Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 91601..92211 Replicon plasmid unnamed
Accession NZ_CP014703
Organism Ralstonia solanacearum strain KACC 10722

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LBM2029_RS16710 Protein ID WP_075465902.1
Coordinates 91903..92211 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LBM2029_RS16705 Protein ID WP_013209163.1
Coordinates 91601..91906 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LBM2029_RS16685 87919..88200 - 282 WP_075465894.1 hypothetical protein -
LBM2029_RS16690 88333..88617 - 285 WP_075465896.1 hypothetical protein -
LBM2029_RS24285 88951..89253 + 303 Protein_71 transposase -
LBM2029_RS16695 89304..89972 + 669 WP_075465898.1 hypothetical protein -
LBM2029_RS16700 90077..91390 - 1314 WP_075465900.1 metabolite/H+ symporter -
LBM2029_RS16705 91601..91906 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
LBM2029_RS16710 91903..92211 - 309 WP_075465902.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LBM2029_RS16715 92296..93495 - 1200 WP_075465903.1 MFS transporter -
LBM2029_RS16720 93623..94438 - 816 WP_075465905.1 GntR family transcriptional regulator -
LBM2029_RS16725 94612..95166 - 555 WP_075465907.1 helix-turn-helix transcriptional regulator -
LBM2029_RS16730 95298..95894 + 597 WP_075465909.1 GNAT family N-acetyltransferase -
LBM2029_RS16735 96150..96584 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1883432 1883432


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-85)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11795.54 Da        Isoelectric Point: 8.5237

>T61716 WP_075465902.1 NZ_CP014703:c92211-91903 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYFSQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T61716 NZ_CP014703:c92211-91903 [Ralstonia solanacearum]
ATGCTGACAATCCGCACGACTGAAATCTTCGACGACTGGTTTTGCAGTCTCCGCGACAAGGCCGCGCAACGTCGCGTCCA
GGTGCGCATCGATCGCCTGCAGATGGGCAATCCAGGCGACGTGAAAGCTGTACGTGAAGGCATCCGTGAGATGCGGATCG
ATCATGGCCCGGGCTATCGCGTGTATTTTTCACAGCGTGGCGTGGTCCTGATCGTCCTGCTGTGCGGCGGTGACAAGTCG
ACGCAGGAAGCCGATGTCCGCCGCGCAATCGACCTGTCCCGCCGTCTTGACGTGGACAACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT61716 WP_013209163.1 NZ_CP014703:c91906-91601 [Ralstonia solanacearum]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT61716 NZ_CP014703:c91906-91601 [Ralstonia solanacearum]
ATGATGATGGCCCAACGCACCATAAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTATCTCGACGCCTGCCTGGAGGAAGCCGGGGATGACCCCGCATTCATCACGCACGCGCTGGGCGTGGTCGCGCGTGCGC
GCGGCATGACGCAGATCGCCCGCGAGACCGGGATGACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References