Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2298358..2298898 Replicon chromosome
Accession NZ_CP014702
Organism Ralstonia solanacearum strain KACC 10722

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LBM2029_RS10375 Protein ID WP_048817440.1
Coordinates 2298358..2298618 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LBM2029_RS10380 Protein ID WP_075464691.1
Coordinates 2298611..2298898 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LBM2029_RS10355 2294475..2295392 - 918 WP_075464683.1 sugar ABC transporter substrate-binding protein -
LBM2029_RS10360 2295610..2296662 - 1053 WP_075464685.1 LacI family DNA-binding transcriptional regulator -
LBM2029_RS10365 2296797..2297954 + 1158 WP_075464687.1 fatty acid desaturase family protein -
LBM2029_RS10370 2297920..2298231 + 312 WP_075464689.1 Rieske 2Fe-2S domain-containing protein -
LBM2029_RS10375 2298358..2298618 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LBM2029_RS10380 2298611..2298898 + 288 WP_075464691.1 putative addiction module antidote protein Antitoxin
LBM2029_RS10385 2298911..2299756 - 846 WP_075464693.1 TIM barrel protein -
LBM2029_RS10390 2299753..2300790 - 1038 WP_075464695.1 xylose isomerase -
LBM2029_RS10395 2300787..2302076 - 1290 WP_075464697.1 FAD-dependent oxidoreductase -
LBM2029_RS10400 2302243..2303160 + 918 WP_075464699.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(8-93)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T61715 WP_048817440.1 NZ_CP014702:2298358-2298618 [Ralstonia solanacearum]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T61715 NZ_CP014702:2298358-2298618 [Ralstonia solanacearum]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCGTCGTTCGGGAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCGCGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10052.47 Da        Isoelectric Point: 4.7361

>AT61715 WP_075464691.1 NZ_CP014702:2298611-2298898 [Ralstonia solanacearum]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARARGITKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT61715 NZ_CP014702:2298611-2298898 [Ralstonia solanacearum]
ATGACTGAGACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
AATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCGCGCGCCCGCGGCATTACCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCATTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References