Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1626658..1627237 Replicon chromosome
Accession NZ_CP014692
Organism Acetobacter aceti strain TMW2.1153

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A0U92_RS07300 Protein ID WP_077812650.1
Coordinates 1626851..1627237 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A0U92_RS07295 Protein ID WP_077814306.1
Coordinates 1626658..1626861 (+) Length 68 a.a.

Genomic Context

A0U92_RS07295A0U92_RS07300A0U92_RS07305A0U92_RS07310A0U92_RS17285A0U92_RS07325A0U92_RS07275A0U92_RS07280A0U92_RS17280A0U92_RS07290A0U92_RS07320
Location: 1626658..1626861 (204 bp)
Type: Antitoxin
Protein ID: WP_077814306.1
Location: 1626851..1627237 (387 bp)
Type: Toxin
Protein ID: WP_077812650.1
Location: 1627473..1628033 (561 bp)
Type: Others
Protein ID: WP_077812651.1
Location: 1628651..1628908 (258 bp)
Type: Others
Protein ID: WP_077812652.1
Location: 1628976..1629344 (369 bp)
Type: Others
Protein ID: WP_149026415.1
Location: 1630516..1631097 (582 bp)
Type: Others
Protein ID: WP_077812655.1
Location: 1622622..1624331 (1710 bp)
Type: Others
Protein ID: WP_149026412.1
Location: 1624337..1624681 (345 bp)
Type: Others
Protein ID: WP_149026413.1
Location: 1625215..1625589 (375 bp)
Type: Others
Protein ID: WP_149026414.1
Location: 1625540..1626457 (918 bp)
Type: Others
Protein ID: WP_077812649.1
Location: 1629708..1630322 (615 bp)
Type: Others
Protein ID: WP_077812654.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A0U92_RS072751622622..1624331-1710WP_149026412.1hypothetical protein-
A0U92_RS072801624337..1624681-345WP_149026413.1MobC family plasmid mobilization relaxosome protein-
A0U92_RS172801625215..1625589-375WP_149026414.1hypothetical protein-
A0U92_RS072901625540..1626457-918WP_077812649.1hypothetical protein-
A0U92_RS072951626658..1626861+204WP_077814306.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
A0U92_RS073001626851..1627237+387WP_077812650.1PIN domain-containing proteinToxin
A0U92_RS073051627473..1628033+561WP_077812651.1recombinase family protein-
A0U92_RS073101628651..1628908+258WP_077812652.1hypothetical protein-
A0U92_RS172851628976..1629344+369WP_149026415.1hypothetical protein-
A0U92_RS073201629708..1630322-615WP_077812654.1hypothetical protein-
A0U92_RS073251630516..1631097+582WP_077812655.1recombinase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-110)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14485.80 Da        Isoelectric Point: 4.5407

>T61694 WP_077812650.1 NZ_CP014692:1626851-1627237 [Acetobacter aceti]
MLLDSNIILYGIIQDDRKTPIADRLMEQGGFLSIQTLNEVTNVLRKKKKDWEFINRLLEDLYISFSVLPVDIEVHKAGVK
IAGRYGLSTYDSMIIGCAYVNGIETVLSEDMQDGQVIFDVVKIINPFS

Download         Length: 387 bp

>T61694 NZ_CP014692:1626851-1627237 [Acetobacter aceti]
ATGCTTCTTGATTCCAATATCATTCTGTATGGCATCATTCAGGATGACAGAAAGACGCCCATTGCTGACAGACTGATGGA
GCAAGGTGGCTTCCTCAGTATTCAGACACTGAATGAAGTCACGAATGTCCTGAGAAAGAAAAAGAAGGACTGGGAGTTCA
TCAACAGGCTTCTGGAAGACCTGTATATCTCCTTTTCCGTTCTGCCTGTGGATATCGAAGTCCATAAGGCAGGCGTGAAG
ATAGCCGGACGTTATGGACTGTCCACCTATGATTCCATGATTATTGGATGTGCGTATGTGAACGGGATTGAGACCGTGTT
GTCCGAGGATATGCAGGATGGACAGGTCATCTTCGATGTCGTGAAGATCATCAATCCGTTCTCATGA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7625.76 Da        Isoelectric Point: 10.1809

>AT61694 WP_077814306.1 NZ_CP014692:1626658-1626861 [Acetobacter aceti]
MQVSKWGNSLAVRIPSHMLKEHGIQEGDNVEITIRRVKSRKEALADLKELGRQLPADFRIERISDAS

Download         Length: 204 bp

>AT61694 NZ_CP014692:1626658-1626861 [Acetobacter aceti]
ATGCAGGTCTCGAAATGGGGAAACAGTCTGGCTGTCCGCATTCCCAGTCACATGTTGAAGGAACATGGTATCCAGGAAGG
CGACAATGTGGAGATTACCATCAGACGGGTAAAATCACGCAAGGAAGCCCTGGCTGATCTGAAGGAACTGGGGAGACAGT
TGCCTGCGGATTTCCGTATCGAACGGATTTCTGATGCTTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References