Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 1626658..1627237 Replicon chromosome
Accession NZ_CP014692
Organism Acetobacter aceti strain TMW2.1153

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A0U92_RS07300 Protein ID WP_077812650.1
Coordinates 1626851..1627237 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A0U92_RS07295 Protein ID WP_077814306.1
Coordinates 1626658..1626861 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A0U92_RS07275 1622622..1624331 - 1710 WP_149026412.1 hypothetical protein -
A0U92_RS07280 1624337..1624681 - 345 WP_149026413.1 MobC family plasmid mobilization relaxosome protein -
A0U92_RS17280 1625215..1625589 - 375 WP_149026414.1 hypothetical protein -
A0U92_RS07290 1625540..1626457 - 918 WP_077812649.1 hypothetical protein -
A0U92_RS07295 1626658..1626861 + 204 WP_077814306.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
A0U92_RS07300 1626851..1627237 + 387 WP_077812650.1 PIN domain-containing protein Toxin
A0U92_RS07305 1627473..1628033 + 561 WP_077812651.1 recombinase family protein -
A0U92_RS07310 1628651..1628908 + 258 WP_077812652.1 hypothetical protein -
A0U92_RS17285 1628976..1629344 + 369 WP_149026415.1 hypothetical protein -
A0U92_RS07320 1629708..1630322 - 615 WP_077812654.1 hypothetical protein -
A0U92_RS07325 1630516..1631097 + 582 WP_077812655.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-110)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14485.80 Da        Isoelectric Point: 4.5407

>T61694 WP_077812650.1 NZ_CP014692:1626851-1627237 [Acetobacter aceti]
MLLDSNIILYGIIQDDRKTPIADRLMEQGGFLSIQTLNEVTNVLRKKKKDWEFINRLLEDLYISFSVLPVDIEVHKAGVK
IAGRYGLSTYDSMIIGCAYVNGIETVLSEDMQDGQVIFDVVKIINPFS

Download         Length: 387 bp

>T61694 NZ_CP014692:1626851-1627237 [Acetobacter aceti]
ATGCTTCTTGATTCCAATATCATTCTGTATGGCATCATTCAGGATGACAGAAAGACGCCCATTGCTGACAGACTGATGGA
GCAAGGTGGCTTCCTCAGTATTCAGACACTGAATGAAGTCACGAATGTCCTGAGAAAGAAAAAGAAGGACTGGGAGTTCA
TCAACAGGCTTCTGGAAGACCTGTATATCTCCTTTTCCGTTCTGCCTGTGGATATCGAAGTCCATAAGGCAGGCGTGAAG
ATAGCCGGACGTTATGGACTGTCCACCTATGATTCCATGATTATTGGATGTGCGTATGTGAACGGGATTGAGACCGTGTT
GTCCGAGGATATGCAGGATGGACAGGTCATCTTCGATGTCGTGAAGATCATCAATCCGTTCTCATGA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7625.76 Da        Isoelectric Point: 10.1809

>AT61694 WP_077814306.1 NZ_CP014692:1626658-1626861 [Acetobacter aceti]
MQVSKWGNSLAVRIPSHMLKEHGIQEGDNVEITIRRVKSRKEALADLKELGRQLPADFRIERISDAS

Download         Length: 204 bp

>AT61694 NZ_CP014692:1626658-1626861 [Acetobacter aceti]
ATGCAGGTCTCGAAATGGGGAAACAGTCTGGCTGTCCGCATTCCCAGTCACATGTTGAAGGAACATGGTATCCAGGAAGG
CGACAATGTGGAGATTACCATCAGACGGGTAAAATCACGCAAGGAAGCCCTGGCTGATCTGAAGGAACTGGGGAGACAGT
TGCCTGCGGATTTCCGTATCGAACGGATTTCTGATGCTTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References