Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 58834..59426 Replicon plasmid pKB16680_2
Accession NZ_CP014683
Organism Kozakia baliensis strain NBRC 16680

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag A0U90_RS14225 Protein ID WP_070406205.1
Coordinates 58834..59136 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag A0U90_RS14230 Protein ID WP_070406206.1
Coordinates 59133..59426 (+) Length 98 a.a.

Genomic Context

A0U90_RS14190A0U90_RS15530A0U90_RS14210A0U90_RS14215A0U90_RS14220A0U90_RS14225A0U90_RS14230A0U90_RS14235A0U90_RS14240A0U90_RS14200A0U90_RS14205A0U90_RS14250A0U90_RS14255A0U90_RS14260A0U90_RS14265
Location: 54414..54722 (309 bp)
Type: Others
Protein ID: WP_070406199.1
Location: 54709..54849 (141 bp)
Type: Others
Protein ID: WP_158513431.1
Location: 57433..57924 (492 bp)
Type: Others
Protein ID: WP_070406203.1
Location: 57990..58496 (507 bp)
Type: Others
Protein ID: WP_083301988.1
Location: 58546..58746 (201 bp)
Type: Others
Protein ID: WP_070406204.1
Location: 58834..59136 (303 bp)
Type: Toxin
Protein ID: WP_070406205.1
Location: 59133..59426 (294 bp)
Type: Antitoxin
Protein ID: WP_070406206.1
Location: 59441..59761 (321 bp)
Type: Others
Protein ID: WP_070406207.1
Location: 59800..60099 (300 bp)
Type: Others
Protein ID: WP_193403473.1
Location: 55190..56299 (1110 bp)
Type: Others
Protein ID: WP_070406201.1
Location: 56407..56997 (591 bp)
Type: Others
Protein ID: WP_151199955.1
Location: 60561..61361 (801 bp)
Type: Others
Protein ID: WP_070406209.1
Location: 61463..61897 (435 bp)
Type: Others
Protein ID: WP_151199956.1
Location: 61927..62754 (828 bp)
Type: Others
Protein ID: WP_070406211.1
Location: 62754..63344 (591 bp)
Type: Others
Protein ID: WP_070406212.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A0U90_RS1419054414..54722+309WP_070406199.1hypothetical protein-
A0U90_RS1553054709..54849+141WP_158513431.1hypothetical protein-
A0U90_RS1420055190..56299-1110WP_070406201.1hypothetical protein-
A0U90_RS1420556407..56997-591WP_151199955.1hypothetical protein-
A0U90_RS1421057433..57924+492WP_070406203.1single-stranded DNA-binding protein-
A0U90_RS1421557990..58496+507WP_083301988.1hypothetical protein-
A0U90_RS1422058546..58746+201WP_070406204.1hypothetical protein-
A0U90_RS1422558834..59136+303WP_070406205.1type II toxin-antitoxin system RelE/ParE family toxinToxin
A0U90_RS1423059133..59426+294WP_070406206.1putative addiction module antidote proteinAntitoxin
A0U90_RS1423559441..59761+321WP_070406207.1hypothetical protein-
A0U90_RS1424059800..60099+300WP_193403473.1hypothetical protein-
A0U90_RS1425060561..61361-801WP_070406209.1hypothetical protein-
A0U90_RS1425561463..61897-435WP_151199956.1hypothetical protein-
A0U90_RS1426061927..62754-828WP_070406211.1ATP-binding protein-
A0U90_RS1426562754..63344-591WP_070406212.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..8809988099


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(11-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11448.31 Da        Isoelectric Point: 10.7436

>T61692 WP_070406205.1 NZ_CP014683:58834-59136 [Kozakia baliensis]
MMQVQQTRQFREWLATLRDQRAAAKIRARLILMEAGAFGDVEPCGEGISETRLHYGPGYRIYFVQRGNVLVIVLGGGTKR
TQPKDIRRAKELARDVEKFL

Download         Length: 303 bp

>T61692 NZ_CP014683:58834-59136 [Kozakia baliensis]
ATGATGCAGGTTCAGCAGACACGCCAGTTTCGCGAATGGCTTGCCACCCTACGAGATCAGAGAGCAGCGGCCAAAATCCG
TGCCCGTCTGATCCTTATGGAAGCCGGGGCGTTCGGGGATGTCGAACCGTGCGGAGAAGGTATTTCCGAAACCCGTCTGC
ATTACGGGCCAGGTTATCGCATTTACTTTGTGCAGCGCGGAAACGTGCTTGTCATTGTGCTTGGCGGCGGCACGAAACGA
ACGCAGCCGAAAGACATCAGGCGGGCGAAGGAATTGGCCCGCGACGTGGAGAAATTCCTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 9968.33 Da        Isoelectric Point: 4.9373

>AT61692 WP_070406206.1 NZ_CP014683:59133-59426 [Kozakia baliensis]
MSDRAELEVFDSVSAAADPAVQVELLNMAWADGDSAGIAHALAVIAKARGMSTTAADAGLTRPALYKALSERGNPSLSSL
LGIMNALGVKAHFQISN

Download         Length: 294 bp

>AT61692 NZ_CP014683:59133-59426 [Kozakia baliensis]
ATGAGTGACCGGGCAGAACTTGAGGTGTTCGATTCCGTCTCGGCGGCCGCCGATCCTGCGGTGCAGGTTGAATTGCTGAA
TATGGCATGGGCGGATGGTGACAGCGCCGGAATTGCCCACGCTCTTGCCGTTATAGCGAAAGCCCGTGGTATGAGCACGA
CAGCGGCAGACGCTGGCCTGACTCGCCCAGCTCTTTATAAGGCGTTGTCGGAGCGGGGAAACCCGAGCCTCTCCAGCTTG
CTAGGCATTATGAACGCTCTCGGCGTGAAAGCGCATTTCCAGATTTCAAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References