Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 58834..59426 Replicon plasmid pKB16680_2
Accession NZ_CP014683
Organism Kozakia baliensis strain NBRC 16680

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag A0U90_RS14225 Protein ID WP_070406205.1
Coordinates 58834..59136 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag A0U90_RS14230 Protein ID WP_070406206.1
Coordinates 59133..59426 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A0U90_RS14190 54414..54722 + 309 WP_070406199.1 hypothetical protein -
A0U90_RS15530 54709..54849 + 141 WP_158513431.1 hypothetical protein -
A0U90_RS14200 55190..56299 - 1110 WP_070406201.1 hypothetical protein -
A0U90_RS14205 56407..56997 - 591 WP_151199955.1 hypothetical protein -
A0U90_RS14210 57433..57924 + 492 WP_070406203.1 single-stranded DNA-binding protein -
A0U90_RS14215 57990..58496 + 507 WP_083301988.1 hypothetical protein -
A0U90_RS14220 58546..58746 + 201 WP_070406204.1 hypothetical protein -
A0U90_RS14225 58834..59136 + 303 WP_070406205.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A0U90_RS14230 59133..59426 + 294 WP_070406206.1 putative addiction module antidote protein Antitoxin
A0U90_RS14235 59441..59761 + 321 WP_070406207.1 hypothetical protein -
A0U90_RS14240 59800..60099 + 300 WP_193403473.1 hypothetical protein -
A0U90_RS14250 60561..61361 - 801 WP_070406209.1 hypothetical protein -
A0U90_RS14255 61463..61897 - 435 WP_151199956.1 hypothetical protein -
A0U90_RS14260 61927..62754 - 828 WP_070406211.1 ATP-binding protein -
A0U90_RS14265 62754..63344 - 591 WP_070406212.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..88099 88099


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(11-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11448.31 Da        Isoelectric Point: 10.7436

>T61692 WP_070406205.1 NZ_CP014683:58834-59136 [Kozakia baliensis]
MMQVQQTRQFREWLATLRDQRAAAKIRARLILMEAGAFGDVEPCGEGISETRLHYGPGYRIYFVQRGNVLVIVLGGGTKR
TQPKDIRRAKELARDVEKFL

Download         Length: 303 bp

>T61692 NZ_CP014683:58834-59136 [Kozakia baliensis]
ATGATGCAGGTTCAGCAGACACGCCAGTTTCGCGAATGGCTTGCCACCCTACGAGATCAGAGAGCAGCGGCCAAAATCCG
TGCCCGTCTGATCCTTATGGAAGCCGGGGCGTTCGGGGATGTCGAACCGTGCGGAGAAGGTATTTCCGAAACCCGTCTGC
ATTACGGGCCAGGTTATCGCATTTACTTTGTGCAGCGCGGAAACGTGCTTGTCATTGTGCTTGGCGGCGGCACGAAACGA
ACGCAGCCGAAAGACATCAGGCGGGCGAAGGAATTGGCCCGCGACGTGGAGAAATTCCTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 9968.33 Da        Isoelectric Point: 4.9373

>AT61692 WP_070406206.1 NZ_CP014683:59133-59426 [Kozakia baliensis]
MSDRAELEVFDSVSAAADPAVQVELLNMAWADGDSAGIAHALAVIAKARGMSTTAADAGLTRPALYKALSERGNPSLSSL
LGIMNALGVKAHFQISN

Download         Length: 294 bp

>AT61692 NZ_CP014683:59133-59426 [Kozakia baliensis]
ATGAGTGACCGGGCAGAACTTGAGGTGTTCGATTCCGTCTCGGCGGCCGCCGATCCTGCGGTGCAGGTTGAATTGCTGAA
TATGGCATGGGCGGATGGTGACAGCGCCGGAATTGCCCACGCTCTTGCCGTTATAGCGAAAGCCCGTGGTATGAGCACGA
CAGCGGCAGACGCTGGCCTGACTCGCCCAGCTCTTTATAAGGCGTTGTCGGAGCGGGGAAACCCGAGCCTCTCCAGCTTG
CTAGGCATTATGAACGCTCTCGGCGTGAAAGCGCATTTCCAGATTTCAAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References