Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 17601..18163 Replicon plasmid pKB16680_1
Accession NZ_CP014682
Organism Kozakia baliensis strain NBRC 16680

Toxin (Protein)


Gene name relE Uniprot ID A0A1D8UXM1
Locus tag A0U90_RS13210 Protein ID WP_070403865.1
Coordinates 17601..17882 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A0U90_RS13215 Protein ID WP_070406047.1
Coordinates 17879..18163 (-) Length 95 a.a.

Genomic Context

A0U90_RS13180A0U90_RS13185A0U90_RS13190A0U90_RS13195A0U90_RS13200A0U90_RS13260A0U90_RS13170A0U90_RS13205A0U90_RS13210A0U90_RS13215A0U90_RS13220A0U90_RS13225A0U90_RS13230A0U90_RS13235A0U90_RS13240A0U90_RS15510A0U90_RS13245A0U90_RS13250A0U90_RS13255
Location: 13825..14430 (606 bp)
Type: Others
Protein ID: WP_051625851.1
Location: 14427..15254 (828 bp)
Type: Others
Protein ID: WP_070406043.1
Location: 15251..15718 (468 bp)
Type: Others
Protein ID: WP_070406044.1
Location: 15877..16620 (744 bp)
Type: Others
Protein ID: WP_151199948.1
Location: 16648..17049 (402 bp)
Type: Others
Protein ID: WP_151199949.1
Location: 22705..22908 (204 bp)
Type: Others
Protein ID: WP_070406053.1
Location: 12638..13396 (759 bp)
Type: Others
Protein ID: WP_070406041.1
Location: 17216..17419 (204 bp)
Type: Others
Protein ID: WP_070404055.1
Location: 17601..17882 (282 bp)
Type: Toxin
Protein ID: WP_070403865.1
Location: 17879..18163 (285 bp)
Type: Antitoxin
Protein ID: WP_070406047.1
Location: 18245..18445 (201 bp)
Type: Others
Protein ID: WP_070406048.1
Location: 18495..18980 (486 bp)
Type: Others
Protein ID: WP_083301972.1
Location: 18977..19417 (441 bp)
Type: Others
Protein ID: WP_070404050.1
Location: 19483..19974 (492 bp)
Type: Others
Protein ID: WP_070406049.1
Location: 20221..20430 (210 bp)
Type: Others
Protein ID: WP_151199932.1
Location: 20939..21079 (141 bp)
Type: Others
Protein ID: WP_158513431.1
Location: 21066..21374 (309 bp)
Type: Others
Protein ID: WP_070406051.1
Location: 21447..22127 (681 bp)
Type: Others
Protein ID: WP_029605140.1
Location: 22450..22713 (264 bp)
Type: Others
Protein ID: WP_070406052.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A0U90_RS1317012638..13396-759WP_070406041.1hypothetical protein-
A0U90_RS1318013825..14430+606WP_051625851.1hypothetical protein-
A0U90_RS1318514427..15254+828WP_070406043.1hypothetical protein-
A0U90_RS1319015251..15718+468WP_070406044.1hypothetical protein-
A0U90_RS1319515877..16620+744WP_151199948.1hypothetical protein-
A0U90_RS1320016648..17049+402WP_151199949.1hypothetical protein-
A0U90_RS1320517216..17419-204WP_070404055.1hypothetical protein-
A0U90_RS1321017601..17882-282WP_070403865.1type II toxin-antitoxin system RelE/ParE family toxinToxin
A0U90_RS1321517879..18163-285WP_070406047.1ribbon-helix-helix protein, CopG familyAntitoxin
A0U90_RS1322018245..18445-201WP_070406048.1hypothetical protein-
A0U90_RS1322518495..18980-486WP_083301972.1hypothetical protein-
A0U90_RS1323018977..19417-441WP_070404050.1hypothetical protein-
A0U90_RS1323519483..19974-492WP_070406049.1single-stranded DNA-binding protein-
A0U90_RS1324020221..20430-210WP_151199932.1hypothetical protein-
A0U90_RS1551020939..21079-141WP_158513431.1hypothetical protein-
A0U90_RS1324521066..21374-309WP_070406051.1hypothetical protein-
A0U90_RS1325021447..22127-681WP_029605140.1hypothetical protein-
A0U90_RS1325522450..22713-264WP_070406052.1hypothetical protein-
A0U90_RS1326022705..22908+204WP_070406053.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..135727135727


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(11-48)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10868.42 Da        Isoelectric Point: 5.6327

>T61691 WP_070403865.1 NZ_CP014682:c17882-17601 [Kozakia baliensis]
VKLQWSAKALSDLHDLTREFESPRTAARIIQRLVAVPDVLAEFPRMGVALADFAPREVRRFIVDDYEIRYELTDAVLIVT
DIFHTRQDRETFH

Download         Length: 282 bp

>T61691 NZ_CP014682:c17882-17601 [Kozakia baliensis]
GTGAAGCTCCAATGGTCCGCCAAGGCCCTGTCCGACCTGCACGACCTGACCAGAGAATTCGAGAGCCCGCGAACCGCCGC
CCGGATCATTCAGCGTCTCGTCGCCGTTCCCGACGTGCTGGCGGAGTTTCCCCGCATGGGAGTCGCGCTGGCGGATTTCG
CCCCGCGCGAGGTGCGTCGCTTTATCGTGGACGATTACGAGATTCGTTACGAATTGACCGACGCGGTCCTGATCGTCACC
GACATATTCCATACGCGGCAGGATCGGGAGACTTTTCATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10419.77 Da        Isoelectric Point: 5.1532

>AT61691 WP_070406047.1 NZ_CP014682:c18163-17879 [Kozakia baliensis]
MSEKQLSKQTVSVQMPAELVEAMDRYGEAIERPRSWVMREAVSAYLAREDEKNRATRRALADIDAGRVVGHDAVRQWAAS
LDSDTPLPLPVPGA

Download         Length: 285 bp

>AT61691 NZ_CP014682:c18163-17879 [Kozakia baliensis]
ATGAGTGAGAAACAGCTATCCAAGCAGACCGTCAGCGTGCAGATGCCCGCCGAACTGGTCGAGGCCATGGACCGCTATGG
TGAGGCGATCGAGCGGCCCCGCTCATGGGTCATGCGCGAAGCCGTAAGCGCCTATCTCGCCCGTGAGGATGAGAAGAACC
GCGCCACCCGCCGTGCGCTGGCCGACATCGACGCGGGCCGTGTCGTGGGTCATGACGCGGTTCGTCAATGGGCCGCCAGT
CTCGACAGCGATACCCCGCTACCTCTGCCGGTGCCCGGGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1D8UXM1

Antitoxin

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Source
ID
Structure
No matching records found

References