Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4689..5359 Replicon plasmid pKB14400_5
Accession NZ_CP014679
Organism Kozakia baliensis strain DSM 14400

Toxin (Protein)


Gene name vapC Uniprot ID A0A318PNR1
Locus tag A0U89_RS16485 Protein ID WP_034931108.1
Coordinates 4937..5359 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1D8UZ46
Locus tag A0U89_RS16480 Protein ID WP_010512463.1
Coordinates 4689..4940 (+) Length 84 a.a.

Genomic Context

A0U89_RS16465A0U89_RS16470A0U89_RS16475A0U89_RS16480A0U89_RS16485A0U89_RS16490A0U89_RS16495A0U89_RS16505A0U89_RS16460A0U89_RS16510A0U89_RS16515
Location: 503..3874 (3372 bp)
Type: Others
Protein ID: WP_083278626.1
Location: 3921..4343 (423 bp)
Type: Others
Protein ID: WP_007396294.1
Location: 4340..4603 (264 bp)
Type: Others
Protein ID: WP_070404322.1
Location: 4689..4940 (252 bp)
Type: Antitoxin
Protein ID: WP_010512463.1
Location: 4937..5359 (423 bp)
Type: Toxin
Protein ID: WP_034931108.1
Location: 5424..5618 (195 bp)
Type: Others
Protein ID: WP_070404323.1
Location: 5615..6007 (393 bp)
Type: Others
Protein ID: WP_070404324.1
Location: 6301..6972 (672 bp)
Type: Others
Protein ID: WP_070404342.1
Location: 47..406 (360 bp)
Type: Others
Protein ID: WP_070404321.1
Location: 7146..7931 (786 bp)
Type: Others
Protein ID: WP_070404326.1
Location: 7921..9445 (1525 bp)
Type: Others
Protein ID: Protein_10
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A0U89_RS1646047..406-360WP_070404321.1conjugal transfer protein TraD-
A0U89_RS16465503..3874+3372WP_083278626.1Ti-type conjugative transfer relaxase TraA-
A0U89_RS164703921..4343+423WP_007396294.1putative toxin-antitoxin system toxin component, PIN family-
A0U89_RS164754340..4603+264WP_070404322.1toxin-antitoxin system HicB family antitoxin-
A0U89_RS164804689..4940+252WP_010512463.1plasmid stabilization proteinAntitoxin
A0U89_RS164854937..5359+423WP_034931108.1type II toxin-antitoxin system VapC family toxinToxin
A0U89_RS164905424..5618+195WP_070404323.1type II toxin-antitoxin system VapB family antitoxin-
A0U89_RS164955615..6007+393WP_070404324.1PIN domain nuclease-
A0U89_RS165056301..6972+672WP_070404342.1hypothetical protein-
A0U89_RS165107146..7931-786WP_070404326.1IS21-like element helper ATPase IstB-
A0U89_RS165157921..9445-1525Protein_10IS21 family transposase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..3546335463


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15266.54 Da        Isoelectric Point: 5.2375

>T61687 WP_034931108.1 NZ_CP014679:4937-5359 [Kozakia baliensis]
MILLDTNVISEPWKPVPEPRVLAWIDGQAIETLFLSAVTVAELRFGIGAMPSGRRRSVLHERLEQEVLPLFAGRVLSFDL
AASQAYAELMVRARSEGRAIGKADGYIAATAASRGYVVASRDVSPFEAAGVRVLNPWEET

Download         Length: 423 bp

>T61687 NZ_CP014679:4937-5359 [Kozakia baliensis]
ATGATCCTGCTCGATACCAATGTGATCTCGGAGCCGTGGAAGCCCGTCCCGGAGCCGCGTGTTCTGGCCTGGATCGATGG
ACAGGCGATCGAGACGCTTTTCCTGTCGGCCGTCACGGTGGCGGAGCTGCGTTTCGGGATCGGGGCGATGCCGTCTGGTC
GGCGGCGTTCTGTACTGCATGAGCGGCTGGAACAGGAGGTATTGCCCCTGTTCGCGGGGCGTGTCCTGTCGTTCGATCTG
GCGGCGTCTCAGGCCTATGCCGAACTGATGGTGCGGGCCAGATCAGAGGGCCGCGCAATTGGCAAGGCAGATGGCTATAT
TGCAGCAACCGCTGCATCCCGAGGTTATGTCGTGGCCAGCCGCGACGTGTCTCCTTTCGAGGCGGCCGGTGTGCGGGTTC
TCAATCCGTGGGAGGAGACCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9093.39 Da        Isoelectric Point: 6.4584

>AT61687 WP_010512463.1 NZ_CP014679:4689-4940 [Kozakia baliensis]
MSSVVIRNLPEETHRALKAQAMLHGRSTEAEIRTILEAAVRPPQRVRLGSLLASIGREAGVCDQDIAALQTRDQTPAEPM
SFE

Download         Length: 252 bp

>AT61687 NZ_CP014679:4689-4940 [Kozakia baliensis]
ATGTCCTCTGTGGTTATTCGCAATCTTCCGGAAGAGACGCATCGGGCGCTGAAGGCGCAGGCCATGCTGCATGGGCGCAG
TACGGAAGCAGAGATCCGGACCATTCTGGAAGCGGCCGTCCGGCCGCCGCAGCGGGTCCGGCTGGGATCGCTTCTGGCGT
CCATCGGGCGGGAGGCCGGTGTGTGTGATCAGGATATTGCGGCCTTGCAGACCCGCGATCAGACCCCGGCCGAGCCGATG
TCCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A318PNR1

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1D8UZ46

References