Detailed information of TA system TA061684

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-parD/RelE(toxin)
• Location: 3161343..3161917
• Replicon: chromosome
• Accession: NZ_CP014671
• Organism: Immundisolibacter cernigliae strain TR3.2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PG2T_RS14835
• Protein ID: WP_202816369.1
• Coordinates: 3161630..3161917 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A1B1YXC0
• Locus tag: PG2T_RS14830
• Protein ID: WP_068807242.1
• Coordinates: 3161343..3161633 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PG2T_RS14820	3158090..3159868	+	1779	WP_145931113.1	exodeoxyribonuclease V subunit alpha	-
PG2T_RS14825	3159935..3160891	-	957	WP_202816368.1	transposase	-
PG2T_RS14830	3161343..3161633	+	291	WP_068807242.1	hypothetical protein	Antitoxin
PG2T_RS14835	3161630..3161917	+	288	WP_202816369.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PG2T_RS14840	3162470..3164473	-	2004	WP_145931114.1	tetratricopeptide repeat protein	-
PG2T_RS14845	3164559..3165017	-	459	WP_068807250.1	pilin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10660.00 Da
• Isoelectric Point: 4.6090

>T61684 WP_202816369.1 NZ_CP014671:3161630-3161917 [Immundisolibacter cernigliae]
MMELLWTPEATQDRDEIFDYIEAHNPAAALALDELFAENAGRLVDHPGLGRPGRVAGTRELVAHQNYVLVYDVTGDLVRV
LRVLHAARQWPPDQS

Nucleotide

• Length: 288 bp

>T61684 NZ_CP014671:3161630-3161917 [Immundisolibacter cernigliae]
ATGATGGAGCTACTCTGGACGCCAGAGGCGACACAAGACCGCGACGAAATCTTTGACTACATTGAGGCGCACAACCCCGC
CGCCGCGCTGGCTCTCGATGAACTGTTTGCAGAAAATGCCGGCCGCTTGGTCGATCATCCCGGCCTTGGCCGGCCTGGCC
GTGTCGCTGGCACTCGCGAGCTGGTAGCGCACCAGAATTACGTCCTGGTCTACGACGTGACCGGCGACTTGGTGCGCGTG
CTGCGTGTGCTGCACGCTGCCAGGCAGTGGCCGCCGGACCAGAGTTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10927.26 Da
• Isoelectric Point: 10.2779

>AT61684 WP_068807242.1 NZ_CP014671:3161343-3161633 [Immundisolibacter cernigliae]
MSEVTFTFRVDEALKNQFATAAKKRDRTGAQLLRDFMREFVRQQEEAAEHDAWFRRQVQIGLDSANAGNLIPAAEVEARF
AAKRAATRRRLDASAE

Nucleotide

• Length: 291 bp

>AT61684 NZ_CP014671:3161343-3161633 [Immundisolibacter cernigliae]
ATGAGCGAAGTCACTTTCACTTTCCGGGTCGATGAGGCCCTGAAAAACCAATTCGCCACGGCCGCGAAGAAACGTGACCG
TACCGGCGCGCAGCTCCTGCGCGACTTCATGCGCGAGTTCGTGCGGCAGCAGGAGGAGGCCGCCGAGCATGACGCATGGT
TCCGTCGCCAGGTGCAAATCGGCCTGGATTCGGCCAACGCCGGCAACCTGATCCCGGCGGCCGAAGTAGAAGCCAGGTTC
GCGGCAAAGCGGGCAGCAACGCGCCGCCGGCTTGACGCCTCCGCCGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A1B1YXC0