Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3378600..3378745 Replicon chromosome
Accession NZ_CP014647
Organism Klebsiella pneumoniae strain KPNIH36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3378607..3378709 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3378600..3378745 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABA76_RS17125 3374132..3375565 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ABA76_RS17130 3375681..3375920 + 240 WP_002911393.1 YebV family protein -
ABA76_RS17135 3376018..3376209 + 192 WP_002911395.1 YebW family protein -
ABA76_RS17140 3376206..3376859 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
ABA76_RS17145 3377016..3377984 + 969 WP_004151446.1 VirK/YbjX family protein -
ABA76_RS31015 3378089..3378232 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3378600..3378745 + 146 - - Antitoxin
- 3378607..3378709 - 103 - - Toxin
ABA76_RS17155 3378868..3379206 - 339 WP_002911404.1 YebY family protein -
ABA76_RS17160 3379223..3380092 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
ABA76_RS17165 3380096..3380470 - 375 WP_004151448.1 CopC domain-containing protein YobA -
ABA76_RS17170 3380583..3380813 + 231 WP_002911406.1 DNA polymerase III subunit theta -
ABA76_RS17175 3380892..3381551 + 660 WP_002911407.1 exodeoxyribonuclease X -
ABA76_RS17180 3381555..3383615 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T61628 NZ_CP014647:c3378709-3378607 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT61628 NZ_CP014647:3378600-3378745 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References