Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1354117..1354388 Replicon chromosome
Accession NZ_CP014642
Organism Escherichia coli strain BLK16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1354155..1354258 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1354117..1354388 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYR48_RS06995 1351274..1352713 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AYR48_RS07000 1352831..1353067 + 237 WP_001295499.1 YebV family protein -
AYR48_RS07005 1353172..1353363 + 192 WP_001296140.1 YebW family protein -
AYR48_RS07010 1353364..1354020 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1354117..1354388 + 272 - - Antitoxin
- 1354155..1354258 - 104 - - Toxin
AYR48_RS07015 1354415..1354756 - 342 WP_000976472.1 YebY family protein -
AYR48_RS07020 1354769..1355641 - 873 WP_000879293.1 copper homeostasis membrane protein CopD -
AYR48_RS07025 1355645..1356019 - 375 WP_000168747.1 CopC domain-containing protein YobA -
AYR48_RS07030 1356158..1356388 + 231 WP_000916763.1 DNA polymerase III subunit theta -
AYR48_RS07035 1356490..1357146 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
AYR48_RS07040 1357170..1357832 + 663 WP_000944245.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T61603 NZ_CP014642:c1354258-1354155 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT61603 NZ_CP014642:1354117-1354388 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References