Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2394..2953 Replicon plasmid pSAN1-1727
Accession NZ_CP014622
Organism Salmonella enterica subsp. enterica serovar Anatum str. USDA-ARS-USMARC-1727 isolate SAN1261-1

Toxin (Protein)


Gene name relE Uniprot ID A0A733EV64
Locus tag AW49_RS25135 Protein ID WP_001582571.1
Coordinates 2678..2953 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C1J8K5
Locus tag AW49_RS25130 Protein ID WP_001178089.1
Coordinates 2394..2678 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AW49_RS25110 455..1486 + 1032 WP_000907873.1 replication initiation protein -
AW49_RS25130 2394..2678 + 285 WP_001178089.1 ribbon-helix-helix protein, CopG family Antitoxin
AW49_RS25135 2678..2953 + 276 WP_001582571.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AW49_RS25140 3059..3337 + 279 WP_001105069.1 hypothetical protein -
AW49_RS26400 3532..3798 - 267 WP_000627829.1 hypothetical protein -
AW49_RS25150 3798..4292 - 495 WP_001582574.1 hypothetical protein -
AW49_RS25155 4348..4950 - 603 WP_000517695.1 hypothetical protein -
AW49_RS25165 5304..6650 + 1347 WP_001132032.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..97041 97041


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11810.03 Da        Isoelectric Point: 12.7590

>T61565 WP_001582571.1 NZ_CP014622:2678-2953 [Salmonella enterica subsp. enterica serovar Anatum str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKK

Download         Length: 276 bp

>T61565 NZ_CP014622:2678-2953 [Salmonella enterica subsp. enterica serovar Anatum str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT61565 WP_001178089.1 NZ_CP014622:2394-2678 [Salmonella enterica subsp. enterica serovar Anatum str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT61565 NZ_CP014622:2394-2678 [Salmonella enterica subsp. enterica serovar Anatum str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A733EV64

Antitoxin

Source ID Structure
AlphaFold DB A0A731IHA8

References