Detailed information of TA system TA061507

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpA-AbkA/BrnT_toxin-BrnA
• Location: 4375619..4376224
• Replicon: chromosome
• Accession: NZ_CP014578
• Organism: Paraburkholderia phytofirmans OLGA172

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: AYM40_RS19355
• Protein ID: WP_201788150.1
• Coordinates: 4375919..4376224 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: AbkA
• Uniprot ID: -
• Locus tag: AYM40_RS19350
• Protein ID: WP_063497586.1
• Coordinates: 4375619..4375876 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYM40_RS19330	4370952..4371704	+	753	WP_063497582.1	5-oxoprolinase subunit PxpA	-
AYM40_RS19335	4371809..4372558	+	750	WP_063497583.1	DUF969 domain-containing protein	-
AYM40_RS19340	4372555..4373511	+	957	WP_063497584.1	DUF979 domain-containing protein	-
AYM40_RS19345	4373729..4375534	+	1806	WP_063497585.1	tetratricopeptide repeat protein	-
AYM40_RS19350	4375619..4375876	-	258	WP_063497586.1	BrnA antitoxin family protein	Antitoxin
AYM40_RS19355	4375919..4376224	-	306	WP_201788150.1	BrnT family toxin	Toxin
AYM40_RS19360	4376398..4377549	-	1152	WP_063497588.1	TraB/GumN family protein	-
AYM40_RS19365	4377542..4378561	-	1020	WP_063497589.1	ABC transporter ATP-binding protein	-
AYM40_RS19370	4378558..4379550	-	993	WP_181448431.1	ABC transporter ATP-binding protein	-
AYM40_RS19375	4379645..4380562	-	918	WP_063497590.1	ABC transporter permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (14-91)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (24-77)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 12051.77 Da
• Isoelectric Point: 8.4684

>T61507 WP_201788150.1 NZ_CP014578:c4376224-4375919 [Paraburkholderia phytofirmans OLGA172]
MYRRQYRCCVRFEWDEVKNQINIRKHGIDFSDAVDVFDHPVLTAIDQREDYGEDRWIALGWMAAIVGVVVYVERSADVVR
IISARKATKHEVKRYKYSVWN

Nucleotide

• Length: 306 bp

>T61507 NZ_CP014578:c4376224-4375919 [Paraburkholderia phytofirmans OLGA172]
ATGTACAGACGTCAATACAGGTGCTGTGTGCGGTTTGAATGGGACGAAGTCAAGAATCAAATCAACATTCGTAAGCATGG
CATCGACTTCAGCGATGCTGTCGACGTGTTCGATCACCCGGTGCTGACGGCGATAGACCAGCGGGAAGATTACGGCGAGG
ATCGCTGGATCGCGCTAGGCTGGATGGCCGCCATCGTCGGTGTGGTGGTGTACGTCGAACGCAGTGCCGATGTGGTCCGT
ATCATTTCGGCCCGCAAGGCGACGAAGCACGAGGTCAAACGCTACAAGTACAGCGTCTGGAATTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9688.00 Da
• Isoelectric Point: 9.6915

>AT61507 WP_063497586.1 NZ_CP014578:c4375876-4375619 [Paraburkholderia phytofirmans OLGA172]
MGKTSGTDWKRLAKAGDAHIDTSDVPELGDDFFDRAELHVPPKQAVTMRLDADVLSWFKEQGAGYQTRINKLLRAYMLAQ
QRRRP

Nucleotide

• Length: 258 bp

>AT61507 NZ_CP014578:c4375876-4375619 [Paraburkholderia phytofirmans OLGA172]
ATGGGTAAAACGTCAGGAACGGACTGGAAGCGACTTGCAAAGGCAGGCGACGCGCACATCGACACGAGTGACGTGCCTGA
ATTGGGTGACGATTTTTTTGACCGCGCTGAGCTGCACGTTCCGCCCAAACAGGCTGTGACGATGCGCCTGGATGCGGATG
TGCTGAGTTGGTTCAAAGAACAGGGGGCGGGCTATCAGACGCGCATCAACAAGTTGTTGCGCGCCTACATGCTGGCGCAA
CAGCGCCGTCGTCCTTAG