Detailed information of TA system TA061428

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 1874179..1874671
• Replicon: chromosome
• Accession: NZ_CP014546
• Organism: Pseudomonas azotoformans strain S4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AYR47_RS31980
• Protein ID: WP_082461401.1
• Coordinates: 1874363..1874671 (+)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A127HVD8
• Locus tag: AYR47_RS08725
• Protein ID: WP_033896900.1
• Coordinates: 1874179..1874373 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYR47_RS08705	1869817..1870590	-	774	WP_010213906.1	ABC transporter ATP-binding protein	-
AYR47_RS08710	1871145..1872536	+	1392	WP_033896896.1	GABA permease	-
AYR47_RS08715	1872591..1873004	-	414	WP_033896897.1	hypothetical protein	-
AYR47_RS08720	1873009..1873995	-	987	WP_061434930.1	alpha/beta fold hydrolase	-
AYR47_RS08725	1874179..1874373	+	195	WP_033896900.1	hypothetical protein	Antitoxin
AYR47_RS31980	1874363..1874671	+	309	WP_082461401.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AYR47_RS08730	1874713..1875678	+	966	WP_033896901.1	arsenic resistance protein	-
AYR47_RS08735	1875766..1877358	+	1593	WP_061434932.1	hypothetical protein	-
AYR47_RS08740	1877447..1877722	+	276	WP_061434934.1	hypothetical protein	-
AYR47_RS08750	1878028..1878300	-	273	WP_010213895.1	oxidative damage protection protein	-
AYR47_RS08755	1878297..1879364	-	1068	WP_061434936.1	A/G-specific adenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 11684.61 Da
• Isoelectric Point: 6.9878

>T61428 WP_082461401.1 NZ_CP014546:1874363-1874671 [Pseudomonas azotoformans]
MLVKWRPEAIVALTEIIDFIEQYNPVAAASLHRIIVAATEHLSSMPYGFKQGRLSGTREMVVHPNYLVVYRVMEQVEILT
VLHTRQEYPSDAIVPLHSTLRQ

Nucleotide

• Length: 309 bp

>T61428 NZ_CP014546:1874363-1874671 [Pseudomonas azotoformans]
CTGCTCGTTAAGTGGCGACCCGAGGCTATTGTGGCCTTGACTGAAATTATTGATTTCATTGAGCAGTACAACCCCGTTGC
AGCGGCTTCGCTGCACCGTATCATTGTTGCTGCTACTGAACATTTGTCTTCAATGCCGTATGGATTCAAGCAAGGCCGCT
TGTCAGGCACTCGGGAAATGGTCGTTCATCCAAACTATTTAGTTGTGTATCGAGTGATGGAGCAGGTTGAAATTCTGACC
GTACTGCACACACGTCAAGAATACCCCTCGGATGCAATCGTTCCGCTCCACTCGACCTTGCGCCAATAG

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7440.36 Da
• Isoelectric Point: 5.1186

>AT61428 WP_033896900.1 NZ_CP014546:1874179-1874373 [Pseudomonas azotoformans]
MSIPLSPIVSEFETEEQAASYDRWFRAKVQASIDDPRPSIPHDEALAEVERMLEERRKARRAAR

Nucleotide

• Length: 195 bp

>AT61428 NZ_CP014546:1874179-1874373 [Pseudomonas azotoformans]
ATGAGCATCCCACTTTCTCCCATCGTTTCTGAGTTTGAAACTGAAGAGCAGGCTGCCAGCTATGACCGTTGGTTCCGTGC
CAAGGTGCAGGCTTCGATTGATGATCCTCGACCTAGTATTCCGCATGATGAGGCTCTGGCTGAGGTTGAGAGGATGTTAG
AAGAGAGGCGCAAGGCTCGCCGTGCTGCTCGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A127HVD8