Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 2364916..2365490 Replicon chromosome
Accession NZ_CP014513
Organism Frondihabitans sp. PAMC 28766 strain SR6

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag AX769_RS11405 Protein ID WP_204249385.1
Coordinates 2365134..2365490 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag AX769_RS11400 Protein ID WP_082763762.1
Coordinates 2364916..2365107 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AX769_RS11375 2360519..2361103 - 585 WP_066279311.1 hypothetical protein -
AX769_RS11380 2361234..2362328 + 1095 WP_066279312.1 type I restriction enzyme HsdR N-terminal domain-containing protein -
AX769_RS11385 2362371..2363687 - 1317 WP_066279315.1 hypothetical protein -
AX769_RS11390 2363744..2364094 - 351 WP_157887597.1 hypothetical protein -
AX769_RS11395 2364387..2364734 + 348 WP_066279319.1 DUF4234 domain-containing protein -
AX769_RS11400 2364916..2365107 + 192 WP_082763762.1 hypothetical protein Antitoxin
AX769_RS11405 2365134..2365490 + 357 WP_204249385.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
AX769_RS11410 2365574..2369071 + 3498 WP_066279327.1 bifunctional RecB family nuclease/DEAD/DEAH box helicase -
AX769_RS11415 2369167..2370078 + 912 WP_204249202.1 ADP-ribosylglycohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2339321..2365490 26169


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(16-74)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12322.05 Da        Isoelectric Point: 4.6842

>T61367 WP_204249385.1 NZ_CP014513:2365134-2365490 [Frondihabitans sp. PAMC 28766]
VLIAGSAAFGSALAVRDFGLLDAAVARPQSSVFGLDAYPDVWQKAAALLHSIARNHALVDGNKRTAWAAAWVFLGCNGVS
LRVDFDVDAAYELMIEAAIGETAVPELASALRFFAASA

Download         Length: 357 bp

>T61367 NZ_CP014513:2365134-2365490 [Frondihabitans sp. PAMC 28766]
GTGCTGATTGCGGGGAGCGCGGCGTTCGGCTCTGCTCTCGCGGTCCGAGACTTCGGCCTGCTCGATGCGGCGGTGGCTCG
GCCTCAGAGCTCGGTCTTCGGGCTAGACGCGTACCCAGACGTGTGGCAGAAGGCAGCCGCGCTGCTTCATTCGATCGCTC
GCAATCACGCTTTGGTCGATGGGAACAAGCGCACCGCGTGGGCCGCCGCCTGGGTTTTCTTGGGATGCAATGGCGTGAGT
CTTCGCGTCGACTTCGATGTGGATGCGGCTTACGAGCTCATGATCGAGGCCGCCATCGGAGAGACCGCCGTGCCAGAGCT
GGCGAGCGCGCTGCGCTTCTTCGCCGCATCGGCCTGA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 6843.64 Da        Isoelectric Point: 4.9103

>AT61367 WP_082763762.1 NZ_CP014513:2364916-2365107 [Frondihabitans sp. PAMC 28766]
MPSLNISFSDDELNEIRNAATDLSLKSYVHDAALASARSRKDLVAQLARQIAETSAELNARLA

Download         Length: 192 bp

>AT61367 NZ_CP014513:2364916-2365107 [Frondihabitans sp. PAMC 28766]
ATGCCCTCGCTCAACATCAGCTTCTCGGACGACGAGCTCAATGAGATTCGTAACGCAGCGACCGACCTCTCTCTGAAGTC
GTACGTTCATGACGCGGCGCTCGCGTCCGCGCGCTCGCGAAAAGACCTGGTGGCACAACTCGCCCGACAGATCGCGGAAA
CGTCCGCTGAACTCAACGCTCGGCTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References