Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 253009..253529 Replicon chromosome
Accession NZ_CP014506
Organism Burkholderia sp. PAMC 28687

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag AX768_RS16485 Protein ID WP_172812004.1
Coordinates 253009..253263 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AX768_RS16490 Protein ID WP_062001223.1
Coordinates 253269..253529 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AX768_RS16460 248920..249207 + 288 WP_062001218.1 hypothetical protein -
AX768_RS16465 249261..250403 - 1143 WP_062001219.1 GGDEF domain-containing protein -
AX768_RS16470 250793..251482 + 690 WP_082778902.1 nucleoside 2-deoxyribosyltransferase -
AX768_RS16475 251491..252246 - 756 WP_062001220.1 DeoR/GlpR family DNA-binding transcription regulator -
AX768_RS16480 252340..252924 + 585 WP_062001221.1 NUDIX domain-containing protein -
AX768_RS16485 253009..253263 - 255 WP_172812004.1 Txe/YoeB family addiction module toxin Toxin
AX768_RS16490 253269..253529 - 261 WP_062001223.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AX768_RS16495 253781..254409 + 629 Protein_240 LysE family translocator -
AX768_RS16500 254446..255633 - 1188 WP_062002271.1 CoA transferase -
AX768_RS16505 255686..256531 - 846 WP_062001224.1 enoyl-CoA hydratase/isomerase family protein -
AX768_RS16510 256482..257774 - 1293 WP_062002272.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10055.40 Da        Isoelectric Point: 7.9830

>T61366 WP_172812004.1 NZ_CP014506:c253263-253009 [Burkholderia sp. PAMC 28687]
MNIMWTAEAWDDYIYWQGQDKKTLKRINQLIKDTQRTPFEGVGKPEPLKANLTGFWSRRIDETNRLVYEVADSQINIVSC
RYHY

Download         Length: 255 bp

>T61366 NZ_CP014506:c253263-253009 [Burkholderia sp. PAMC 28687]
TTGAACATCATGTGGACTGCCGAGGCGTGGGACGATTATATTTATTGGCAGGGGCAAGATAAGAAGACCCTTAAACGGAT
CAACCAGCTTATTAAAGACACCCAGCGAACGCCGTTCGAAGGTGTTGGCAAACCGGAACCGCTGAAGGCTAACTTGACAG
GGTTTTGGTCGCGACGCATCGACGAAACCAATCGCCTGGTTTACGAGGTCGCGGATTCGCAGATCAATATTGTCTCGTGC
CGCTACCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9747.10 Da        Isoelectric Point: 6.2190

>AT61366 WP_062001223.1 NZ_CP014506:c253529-253269 [Burkholderia sp. PAMC 28687]
MRTIPFTEARANLKQVIDNVVDDVDVTLITRRDAPNAIVMSQEHYDSLMETVYLLRSPANIAHLERSIKQLRTGKVKSHE
LDETGA

Download         Length: 261 bp

>AT61366 NZ_CP014506:c253529-253269 [Burkholderia sp. PAMC 28687]
ATGCGCACAATCCCTTTCACCGAGGCTCGCGCTAACCTTAAGCAGGTGATTGATAACGTGGTTGATGACGTCGACGTTAC
GCTTATCACTCGCCGCGATGCACCCAATGCAATAGTCATGTCACAGGAGCATTACGACAGCTTGATGGAGACGGTTTATC
TCCTGCGATCACCAGCGAATATTGCTCATCTCGAGCGGTCTATCAAGCAGTTGCGCACGGGCAAGGTCAAGTCACACGAG
TTGGATGAAACAGGCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References