Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1986049..1986317 Replicon chromosome
Accession NZ_CP014495
Organism Escherichia coli strain SaT040

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1986087..1986189 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1986049..1986317 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AVR72_RS10155 1983208..1984646 + 1439 Protein_1956 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AVR72_RS10160 1984763..1984999 + 237 WP_001295499.1 DUF1480 family protein -
AVR72_RS10165 1985104..1985295 + 192 WP_001296140.1 YebW family protein -
AVR72_RS10170 1985296..1985952 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 1986049..1986317 + 269 - - Antitoxin
- 1986087..1986189 - 103 - - Toxin
AVR72_RS10180 1986347..1986688 - 342 WP_000976472.1 YebY family protein -
AVR72_RS10185 1986701..1987573 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
AVR72_RS10190 1987577..1987951 - 375 WP_000168747.1 CopC domain-containing protein YobA -
AVR72_RS10195 1988090..1988320 + 231 WP_000916763.1 DNA polymerase III subunit theta -
AVR72_RS10200 1988422..1989078 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
AVR72_RS10205 1989102..1989764 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T61301 NZ_CP014495:c1986189-1986087 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT61301 NZ_CP014495:1986049-1986317 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References