Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1786017..1786285 Replicon chromosome
Accession NZ_CP014488
Organism Escherichia coli strain G749

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1786055..1786157 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1786017..1786285 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AVR74_RS08805 1783175..1784614 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AVR74_RS08810 1784731..1784967 + 237 WP_001295499.1 DUF1480 family protein -
AVR74_RS08815 1785072..1785263 + 192 WP_001296140.1 YebW family protein -
AVR74_RS08820 1785264..1785920 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 1786017..1786285 + 269 - - Antitoxin
- 1786055..1786157 - 103 - - Toxin
AVR74_RS08830 1786315..1786656 - 342 WP_000976472.1 YebY family protein -
AVR74_RS08835 1786669..1787541 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
AVR74_RS08840 1787545..1787919 - 375 WP_000168747.1 CopC domain-containing protein YobA -
AVR74_RS08845 1788058..1788288 + 231 WP_000916763.1 DNA polymerase III subunit theta -
AVR74_RS08850 1788389..1789045 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
AVR74_RS08855 1789069..1789731 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T61273 NZ_CP014488:c1786157-1786055 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT61273 NZ_CP014488:1786017-1786285 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References