61257

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3870853..3871372 Replicon chromosome
Accession NZ_CP014477
Organism Acinetobacter pittii strain AP_882

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AYJ52_RS18075 Protein ID WP_031993250.1
Coordinates 3871091..3871372 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AYJ52_RS18070 Protein ID WP_031993249.1
Coordinates 3870853..3871101 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYJ52_RS18040 3866257..3867438 + 1182 WP_033917505.1 DUF3800 domain-containing protein -
AYJ52_RS20475 3867495..3868919 + 1425 WP_079381171.1 hypothetical protein -
AYJ52_RS18055 3869078..3869671 + 594 WP_031993245.1 recombinase family protein -
AYJ52_RS18060 3869675..3870157 + 483 WP_033917506.1 hypothetical protein -
AYJ52_RS18065 3870428..3870850 + 423 WP_033917507.1 hypothetical protein -
AYJ52_RS18070 3870853..3871101 + 249 WP_031993249.1 plasmid stabilization protein Antitoxin
AYJ52_RS18075 3871091..3871372 + 282 WP_031993250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AYJ52_RS18080 3871799..3872629 - 831 WP_033917508.1 hypothetical protein -
AYJ52_RS18085 3872735..3873139 + 405 WP_033917509.1 transcriptional regulator -
AYJ52_RS18090 3873216..3873425 - 210 WP_031993253.1 hypothetical protein -
AYJ52_RS18095 3873442..3874368 - 927 WP_061403595.1 hypothetical protein -
AYJ52_RS18100 3874718..3875098 - 381 WP_033917535.1 hypothetical protein -
AYJ52_RS18105 3875135..3876349 - 1215 WP_033917534.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10854.69 Da        Isoelectric Point: 10.3780

>T61257 WP_031993250.1 NZ_CP014477:3871091-3871372 [Acinetobacter pittii]
MSYELNFLEEALEEWKKLNPSIKQPLKKKLVKVLENPRVPKNKLTGHPNRYKIKLRNAGYRLVYEVIDYEVVVLVIAVGR
RENNAVYNTAGSR

Download         Length: 282 bp

>T61257 NZ_CP014477:3871091-3871372 [Acinetobacter pittii]
ATGAGTTATGAGTTAAACTTTTTAGAAGAAGCATTAGAAGAATGGAAAAAGCTTAATCCCAGTATTAAGCAGCCATTGAA
AAAGAAACTGGTGAAGGTCTTAGAGAATCCTAGAGTTCCTAAGAACAAGCTAACAGGGCATCCTAACCGATATAAAATTA
AACTTCGTAACGCTGGCTATCGTTTGGTTTATGAGGTCATAGATTATGAAGTTGTTGTATTAGTAATTGCTGTAGGAAGA
CGTGAAAATAATGCTGTCTACAATACGGCAGGCTCACGATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9301.74 Da        Isoelectric Point: 5.0506

>AT61257 WP_031993249.1 NZ_CP014477:3870853-3871101 [Acinetobacter pittii]
MTQLIHARMTASITELKKSPMDTVLAGRGEAVAILNRNTPAFYCIPAELYETMIEQLEDLELNQIADTRANQKRIRVNIN
EL

Download         Length: 249 bp

>AT61257 NZ_CP014477:3870853-3871101 [Acinetobacter pittii]
ATGACTCAACTAATCCATGCACGAATGACTGCAAGTATTACTGAACTCAAGAAAAGTCCTATGGATACCGTATTAGCAGG
TAGAGGTGAAGCTGTTGCAATTCTCAACCGTAATACACCTGCTTTCTACTGTATCCCTGCTGAACTCTACGAAACTATGA
TTGAACAGCTAGAAGATTTAGAACTTAATCAAATTGCAGATACTCGTGCGAACCAGAAACGCATCCGAGTAAATATAAAT
GAGTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References