Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 556822..557475 Replicon chromosome
Accession NZ_CP014477
Organism Acinetobacter pittii strain AP_882

Toxin (Protein)


Gene name cptA Uniprot ID A0A009H1K7
Locus tag AYJ52_RS02540 Protein ID WP_017386980.1
Coordinates 556822..557211 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag AYJ52_RS02545 Protein ID WP_002117064.1
Coordinates 557218..557475 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYJ52_RS02525 551913..554123 - 2211 WP_017386978.1 TRAP transporter large permease subunit -
AYJ52_RS02530 554303..554878 - 576 WP_033917330.1 rhombosortase -
AYJ52_RS02535 554963..556051 - 1089 WP_017403242.1 hypothetical protein -
AYJ52_RS02540 556822..557211 - 390 WP_017386980.1 hypothetical protein Toxin
AYJ52_RS02545 557218..557475 - 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
AYJ52_RS02550 557664..558836 + 1173 WP_017403243.1 acyl-CoA dehydrogenase family protein -
AYJ52_RS02555 558887..560377 - 1491 WP_017403244.1 NAD(P)/FAD-dependent oxidoreductase -
AYJ52_RS02560 560559..560936 - 378 WP_002049717.1 50S ribosomal protein L17 -
AYJ52_RS02565 560955..561962 - 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15509.60 Da        Isoelectric Point: 8.7390

>T61256 WP_017386980.1 NZ_CP014477:c557211-556822 [Acinetobacter pittii]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTLIWWLCAVILLFIGSIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRAEITKIIDYQLFVVIYFEETPTNIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

>T61256 NZ_CP014477:c557211-556822 [Acinetobacter pittii]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGTGTCTCGGTAATATTTCAGCTTTTTGTTGGTTTGGGTTTAGC
AATCCTGCTTTATCAATTATTAACACTGATATGGTGGCTATGTGCTGTCATTCTTCTATTTATTGGTTCTATTTTCTTTC
TAAAGCAAGCACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTTTTCAAAAAAAGAAATT
TACCGTGCAGAAATTACTAAAATAATTGATTATCAGTTATTTGTAGTTATTTATTTTGAAGAGACTCCTACGAATATAGC
TATTGTTTGGTTCGATCAGCTTCCTATTCAGCAGTGGAAAAGATTAAAAGTTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT61256 WP_002117064.1 NZ_CP014477:c557475-557218 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp

>AT61256 NZ_CP014477:c557475-557218 [Acinetobacter pittii]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCGTATGTAAAAAACTATTATTTAAAAGCTGATCCAGCAGAAAAAGCATTATTTGCAGAGCTAGTTGATCAAGAAG
ATCCAGATTTATTAGATTGGTTCATGGAAGTTTCTGAGCCTCCACGTACTGAGTTACGTGAATTTATTTATAAACTAAAA
CAGTATGTGCATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A009H1K7

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References