Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3410775..3411046 Replicon chromosome
Accession NZ_CP014348
Organism Escherichia coli str. K-12 substr. MG1655 strain JW5437-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3410905..3411008 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3410775..3411046 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWN69_RS16735 3407330..3407992 - 663 WP_000944256.1 exodeoxyribonuclease X -
AWN69_RS16740 3408016..3408672 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
AWN69_RS16745 3408774..3409004 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AWN69_RS16750 3409143..3409517 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AWN69_RS16755 3409521..3410393 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
AWN69_RS16760 3410406..3410747 + 342 WP_000976476.1 YebY family protein -
- 3410775..3411046 - 272 - - Antitoxin
- 3410905..3411008 + 104 - - Toxin
AWN69_RS16770 3411143..3411799 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AWN69_RS16775 3411800..3411991 - 192 WP_000457842.1 YebW family protein -
AWN69_RS16780 3412096..3412332 - 237 WP_001295499.1 DUF1480 family protein -
AWN69_RS16785 3412450..3413889 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T60771 NZ_CP014348:3410905-3411008 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT60771 NZ_CP014348:c3411046-3410775 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References