Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 863524..864293 Replicon chromosome
Accession NZ_CP014343
Organism Pseudomonas putida strain 1A00316

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag AWT69_RS03855 Protein ID WP_062575677.1
Coordinates 863805..864293 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag AWT69_RS03850 Protein ID WP_081100214.1
Coordinates 863524..863814 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWT69_RS03835 859122..860180 + 1059 WP_062572792.1 bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada -
AWT69_RS03840 860235..862637 + 2403 WP_062572793.1 mechanosensitive ion channel family protein -
AWT69_RS03845 862796..863053 - 258 WP_062572794.1 hypothetical protein -
AWT69_RS03850 863524..863814 + 291 WP_081100214.1 DUF1778 domain-containing protein Antitoxin
AWT69_RS03855 863805..864293 + 489 WP_062575677.1 hypothetical protein Toxin
AWT69_RS03860 864315..864551 - 237 WP_062572795.1 hypothetical protein -
AWT69_RS03865 864642..866072 - 1431 WP_062572796.1 aldehyde dehydrogenase family protein -
AWT69_RS03870 866086..867585 - 1500 WP_062572797.1 cytosine permease -
AWT69_RS03875 867673..868062 - 390 WP_062572798.1 nuclear transport factor 2 family protein -
AWT69_RS26280 868507..868653 + 147 WP_155721629.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(15-91)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17259.93 Da        Isoelectric Point: 8.4842

>T60749 WP_062575677.1 NZ_CP014343:863805-864293 [Pseudomonas putida]
MELSAPQKLEAFHELGQFDCGEASINGYLREKAYKAQIAKHAVVYVTCFKGTSVVAGYYTLSTGSVARAHGSSASVRRNA
PNDLPVVVLGRMGVTLRAAGQGVATDLLQDAVERALVASEIVGCVAMIVHPLDARLERFYANAAGFTSCPQLSPKTMMLA
LR

Download         Length: 489 bp

>T60749 NZ_CP014343:863805-864293 [Pseudomonas putida]
CTGGAGCTGAGCGCTCCGCAGAAGCTCGAAGCGTTTCATGAGCTAGGTCAGTTCGACTGTGGAGAGGCGTCGATCAATGG
CTACCTTCGAGAAAAGGCTTACAAGGCGCAGATAGCGAAGCACGCAGTGGTGTATGTCACCTGCTTCAAGGGCACGTCAG
TTGTGGCCGGTTACTACACGCTTTCGACGGGATCTGTGGCGCGTGCCCATGGTTCTTCTGCAAGCGTGCGACGCAATGCT
CCAAATGACTTGCCGGTGGTGGTGCTGGGGCGAATGGGGGTAACCCTGAGAGCTGCTGGGCAAGGGGTCGCCACCGACCT
TTTGCAGGATGCTGTCGAGAGAGCTCTGGTGGCATCCGAGATCGTCGGATGTGTTGCAATGATCGTGCATCCACTTGATG
CGCGTCTGGAGCGTTTCTATGCCAACGCTGCGGGCTTCACATCCTGTCCACAGCTGTCACCGAAGACGATGATGCTTGCT
CTGCGGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11073.70 Da        Isoelectric Point: 5.8983

>AT60749 WP_081100214.1 NZ_CP014343:863524-863814 [Pseudomonas putida]
MSDLQIKDRSKAVPLNMRVAEHRRDLIDAAVEIVGGDRTSFVLDAACRRAEEVLMERRLFLLDDEAFDQFTQALEDSPIR
SNECVKKLLARPKRWS

Download         Length: 291 bp

>AT60749 NZ_CP014343:863524-863814 [Pseudomonas putida]
ATGAGCGATTTACAGATCAAGGATCGGAGCAAGGCCGTACCGCTGAACATGCGGGTGGCCGAGCATCGCAGAGACCTCAT
CGATGCCGCCGTGGAGATTGTGGGCGGTGACCGCACCAGCTTCGTTCTCGATGCGGCTTGCCGACGCGCTGAGGAAGTAC
TGATGGAGCGCCGGTTGTTCCTGCTTGATGACGAAGCCTTCGATCAATTCACCCAGGCGCTTGAAGACAGCCCCATCAGG
AGCAATGAATGCGTGAAGAAGCTGTTGGCAAGGCCGAAGCGCTGGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References