Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 406901..407421 Replicon chromosome
Accession NZ_CP014315
Organism Burkholderia sp. PAMC 26561

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag AXG89_RS36530 Protein ID WP_172812004.1
Coordinates 407167..407421 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AXG89_RS36525 Protein ID WP_062001223.1
Coordinates 406901..407161 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXG89_RS36505 402876..403721 + 846 WP_075360070.1 enoyl-CoA hydratase/isomerase family protein -
AXG89_RS36510 403774..404961 + 1188 WP_075360339.1 CoA transferase -
AXG89_RS36515 405123..406022 + 900 WP_075360071.1 DMT family transporter -
AXG89_RS36520 406029..406658 - 630 WP_075360072.1 LysE family translocator -
AXG89_RS36525 406901..407161 + 261 WP_062001223.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AXG89_RS36530 407167..407421 + 255 WP_172812004.1 Txe/YoeB family addiction module toxin Toxin
AXG89_RS36535 407506..408090 - 585 WP_075360340.1 NUDIX domain-containing protein -
AXG89_RS36540 408184..408939 + 756 WP_075360341.1 DeoR/GlpR family DNA-binding transcription regulator -
AXG89_RS36545 408948..409562 - 615 WP_083638129.1 nucleoside 2-deoxyribosyltransferase -
AXG89_RS36550 410026..411168 + 1143 WP_075360073.1 GGDEF domain-containing protein -
AXG89_RS36555 411188..411475 - 288 WP_075360074.1 hypothetical protein -
AXG89_RS36560 411751..412401 + 651 WP_075360075.1 YukJ family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10055.40 Da        Isoelectric Point: 7.9830

>T60691 WP_172812004.1 NZ_CP014315:407167-407421 [Burkholderia sp. PAMC 26561]
MNIMWTAEAWDDYIYWQGQDKKTLKRINQLIKDTQRTPFEGVGKPEPLKANLTGFWSRRIDETNRLVYEVADSQINIVSC
RYHY

Download         Length: 255 bp

>T60691 NZ_CP014315:407167-407421 [Burkholderia sp. PAMC 26561]
TTGAACATCATGTGGACTGCCGAGGCGTGGGACGATTATATTTATTGGCAGGGGCAAGATAAGAAGACCCTTAAACGGAT
CAACCAGCTTATTAAAGACACCCAGCGAACGCCGTTCGAAGGTGTTGGCAAACCGGAACCGCTGAAGGCTAACCTGACAG
GGTTTTGGTCGCGACGCATCGACGAAACCAATCGCCTGGTTTACGAGGTCGCGGATTCGCAGATCAATATTGTCTCGTGC
CGCTACCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9747.10 Da        Isoelectric Point: 6.2190

>AT60691 WP_062001223.1 NZ_CP014315:406901-407161 [Burkholderia sp. PAMC 26561]
MRTIPFTEARANLKQVIDNVVDDVDVTLITRRDAPNAIVMSQEHYDSLMETVYLLRSPANIAHLERSIKQLRTGKVKSHE
LDETGA

Download         Length: 261 bp

>AT60691 NZ_CP014315:406901-407161 [Burkholderia sp. PAMC 26561]
ATGCGCACAATCCCTTTCACCGAGGCTCGCGCTAACCTTAAGCAGGTGATTGATAACGTGGTTGATGACGTCGACGTTAC
GCTTATCACTCGCCGCGATGCACCCAATGCAATAGTCATGTCACAGGAGCATTACGACAGCTTGATGGAGACGGTTTATC
TCCTGCGATCACCAGCGAATATTGCTCATCTCGAGCGGTCTATCAAGCAGTTGCGCACGGGCAAGGTCAAGTCACACGAG
TTGGATGAAACAGGCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References