Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1536369..1536640 Replicon chromosome
Accession NZ_CP014314
Organism Escherichia coli O157:H7 strain JEONG-1266

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1536499..1536602 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1536369..1536640 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JEONG1266_RS08135 1532924..1533586 - 663 WP_000944244.1 exodeoxyribonuclease X -
JEONG1266_RS08140 1533610..1534266 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
JEONG1266_RS08145 1534368..1534598 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JEONG1266_RS08150 1534737..1535111 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JEONG1266_RS08155 1535115..1535987 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JEONG1266_RS08160 1536000..1536341 + 342 WP_000976483.1 YebY family protein -
- 1536369..1536640 - 272 - - Antitoxin
- 1536499..1536602 + 104 - - Toxin
JEONG1266_RS08170 1536737..1537393 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JEONG1266_RS08175 1537394..1537585 - 192 WP_001296140.1 YebW family protein -
JEONG1266_RS08180 1537690..1537926 - 237 WP_001295499.1 DUF1480 family protein -
JEONG1266_RS08185 1538044..1539483 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T60661 NZ_CP014314:1536499-1536602 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT60661 NZ_CP014314:c1536640-1536369 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References