Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 704886..705811 Replicon plasmid unnamed2
Accession NZ_CP014309
Organism Burkholderia sp. PAMC 26561

Toxin (Protein)


Gene name slvT Uniprot ID A0A0X8LAF1
Locus tag AXG89_RS30000 Protein ID WP_062172842.1
Coordinates 705290..705811 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID A0A0X8LAL5
Locus tag AXG89_RS29995 Protein ID WP_062172844.1
Coordinates 704886..705293 (+) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXG89_RS29975 700366..701085 - 720 WP_062172852.1 IS4 family transposase -
AXG89_RS29980 701369..701632 - 264 WP_162916116.1 hypothetical protein -
AXG89_RS29985 701852..703402 - 1551 WP_062172849.1 methyl-accepting chemotaxis protein -
AXG89_RS29990 704074..704379 - 306 WP_062172847.1 flagellar biosynthesis anti-sigma factor FlgM -
AXG89_RS29995 704886..705293 + 408 WP_062172844.1 DUF2384 domain-containing protein Antitoxin
AXG89_RS30000 705290..705811 + 522 WP_062172842.1 RES family NAD+ phosphorylase Toxin
AXG89_RS30005 705964..706179 - 216 WP_062172840.1 hypothetical protein -
AXG89_RS30015 706571..706993 + 423 WP_062172838.1 hypothetical protein -
AXG89_RS30020 706987..707334 + 348 WP_162916115.1 IS66 family insertion sequence element accessory protein TnpB -
AXG89_RS30025 707385..708908 + 1524 WP_062172836.1 IS66 family transposase -
AXG89_RS30030 708923..709414 + 492 WP_062172834.1 hypothetical protein -
AXG89_RS30035 709525..709782 + 258 WP_119024714.1 DUF3390 domain-containing protein -
AXG89_RS30040 709821..710378 + 558 WP_082771581.1 LUD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..793876 793876


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(10-156)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19165.66 Da        Isoelectric Point: 5.5882

>T60654 WP_062172842.1 NZ_CP014309:705290-705811 [Burkholderia sp. PAMC 26561]
MIFANLSDVTVYRMLVPKWAVAPMSGAGAGTHGGRANRVGLNALYLGLDHDTAVREYQQLSSLMPPGTLVSYSLTAAPIV
DFTGGYESGKWSPLWEDFYCDWRHCWFNERIEPPSWIIGDEVVSSGAKGILFKSRLTPNGKNLVLYTENLDATDRLDVFD
PHNALPKNQSSWG

Download         Length: 522 bp

>T60654 NZ_CP014309:705290-705811 [Burkholderia sp. PAMC 26561]
ATGATTTTTGCGAACCTGTCCGACGTGACCGTATATCGGATGCTCGTCCCAAAGTGGGCAGTCGCGCCGATGAGCGGCGC
TGGAGCAGGAACGCATGGCGGTCGCGCGAATCGTGTCGGACTCAACGCGCTTTATCTGGGATTGGATCACGACACTGCCG
TCAGAGAGTATCAGCAACTCTCGTCCTTGATGCCACCAGGGACGCTGGTTAGCTACAGCCTCACGGCCGCCCCTATTGTC
GATTTCACCGGCGGATACGAGAGTGGCAAGTGGTCTCCTTTGTGGGAGGATTTTTATTGCGATTGGCGCCACTGCTGGTT
CAATGAACGGATCGAGCCACCAAGTTGGATCATCGGCGATGAGGTCGTCTCGAGCGGCGCCAAAGGCATCCTCTTCAAAT
CACGACTAACACCTAACGGCAAGAATCTCGTTCTGTACACAGAGAATTTGGACGCAACAGATCGTCTCGACGTTTTCGAT
CCGCACAATGCACTGCCGAAAAATCAGTCGTCGTGGGGTTGA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14861.68 Da        Isoelectric Point: 5.1774

>AT60654 WP_062172844.1 NZ_CP014309:704886-705293 [Burkholderia sp. PAMC 26561]
MNLNADATVPGADIGFDRFMASLRDPDDPAPIVSARRFGEALHIDLQTLAQQAHVHRNTISRQPASESVQRFLRDALRVI
RAATDLAGDVSRALFWYRNEPLPVFDYKTAEQLVSEGRADDIIRFVASLEAGAAG

Download         Length: 408 bp

>AT60654 NZ_CP014309:704886-705293 [Burkholderia sp. PAMC 26561]
ATGAACTTAAATGCAGATGCAACTGTTCCCGGCGCAGACATCGGCTTTGATCGATTTATGGCGTCGTTGCGTGACCCAGA
CGACCCCGCACCAATTGTGTCGGCCCGTCGATTCGGCGAGGCTTTGCATATTGACTTGCAAACCCTGGCGCAGCAAGCGC
ACGTGCACCGCAATACGATCAGCAGGCAACCTGCGTCCGAAAGCGTACAACGGTTTCTTCGTGACGCCCTAAGGGTGATC
CGCGCCGCGACTGATCTTGCAGGCGACGTCTCGAGGGCGCTTTTTTGGTACCGAAACGAACCCCTCCCGGTGTTCGACTA
TAAAACCGCCGAACAATTGGTGTCCGAAGGTCGGGCCGACGATATCATCCGTTTTGTTGCATCCCTCGAAGCGGGCGCGG
CGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0X8LAF1

Antitoxin

Source ID Structure
AlphaFold DB A0A0X8LAL5

References