Detailed information of TA system TA060642

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpA-AbkA/BrnT_toxin-BrnA
• Location: 1767961..1768525
• Replicon: chromosome
• Accession: NZ_CP014306
• Organism: Burkholderia sp. PAMC 26561

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: AXG89_RS08305
• Protein ID: WP_062169151.1
• Coordinates: 1768247..1768525 (-)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: AbkA
• Uniprot ID: -
• Locus tag: AXG89_RS08300
• Protein ID: WP_062169149.1
• Coordinates: 1767961..1768218 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AXG89_RS08275	1763379..1764158	-	780	WP_075360609.1	paraquat-inducible protein A	-
AXG89_RS08280	1764589..1765149	+	561	WP_061998457.1	cytochrome b	-
AXG89_RS08285	1765307..1765879	+	573	WP_062169142.1	YceI family protein	-
AXG89_RS08290	1765924..1766508	+	585	WP_062169144.1	YceI family protein	-
AXG89_RS08295	1766666..1767940	+	1275	WP_062169147.1	MFS transporter	-
AXG89_RS08300	1767961..1768218	-	258	WP_062169149.1	BrnA antitoxin family protein	Antitoxin
AXG89_RS08305	1768247..1768525	-	279	WP_062169151.1	BrnT family toxin	Toxin
AXG89_RS08310	1768712..1769662	-	951	WP_062169153.1	protein translocase subunit SecF	-
AXG89_RS08315	1769680..1771749	-	2070	WP_062169155.1	protein translocase subunit SecD	-
AXG89_RS08320	1771870..1772193	-	324	WP_061998465.1	preprotein translocase subunit YajC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-82)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (35-77)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10721.22 Da
• Isoelectric Point: 8.5612

>T60642 WP_062169151.1 NZ_CP014306:c1768525-1768247 [Burkholderia sp. PAMC 26561]
MRFEWDETKNRSNVRKHGVDFNDAIEIFKHPVLTAADRSEDFGEDRWIALGWMKLIVALVVYVERDGDTVRIISARKATR
PEIKRYGDAISK

Nucleotide

• Length: 279 bp

>T60642 NZ_CP014306:c1768525-1768247 [Burkholderia sp. PAMC 26561]
ATGCGATTCGAGTGGGACGAAACAAAGAATCGGAGCAACGTCCGCAAACACGGCGTCGACTTCAACGACGCTATCGAAAT
CTTCAAGCATCCGGTTCTGACCGCTGCGGATCGCAGCGAGGATTTCGGCGAAGATCGCTGGATTGCGTTGGGGTGGATGA
AACTGATCGTGGCGCTGGTCGTTTATGTAGAGCGCGACGGCGACACCGTGCGGATTATTTCAGCGCGCAAGGCAACGCGA
CCCGAGATAAAACGCTACGGTGACGCTATTTCTAAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9934.29 Da
• Isoelectric Point: 7.0127

>AT60642 WP_062169149.1 NZ_CP014306:c1768218-1767961 [Burkholderia sp. PAMC 26561]
MSKTTKTDWKRLEAMPDSSIDTSEMPELGDEFFLNAELQRPPKQAVTMRLDADVLAWFKEQGEGYQTRINKLLRAYMQAQ
QKRHS

Nucleotide

• Length: 258 bp

>AT60642 NZ_CP014306:c1768218-1767961 [Burkholderia sp. PAMC 26561]
ATGAGCAAAACCACGAAGACTGATTGGAAGCGCCTGGAAGCCATGCCGGATTCCAGTATCGACACAAGCGAGATGCCCGA
GCTCGGCGACGAGTTCTTCCTGAACGCCGAGCTGCAAAGACCGCCCAAGCAGGCGGTCACCATGCGTCTAGACGCCGACG
TGCTGGCTTGGTTCAAGGAACAAGGCGAGGGTTACCAGACGCGCATCAACAAGCTTTTGCGCGCCTACATGCAGGCGCAA
CAAAAGCGCCACTCGTAA