Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VapB |
Location | 3627148..3627716 | Replicon | chromosome |
Accession | NZ_CP014301 | ||
Organism | Bosea sp. PAMC 26642 strain PAMC26642 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A126NYV3 |
Locus tag | AXW83_RS17440 | Protein ID | WP_066615469.1 |
Coordinates | 3627148..3627522 (-) | Length | 125 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | A0A126NYF1 |
Locus tag | AXW83_RS17445 | Protein ID | WP_066615471.1 |
Coordinates | 3627519..3627716 (-) | Length | 66 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AXW83_RS17415 (AXW83_17420) | 3622616..3623770 | + | 1155 | WP_066615463.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
AXW83_RS17420 (AXW83_17425) | 3623878..3624468 | - | 591 | WP_082767204.1 | hypothetical protein | - |
AXW83_RS17425 (AXW83_17430) | 3624561..3625082 | - | 522 | WP_066615465.1 | cysteine dioxygenase family protein | - |
AXW83_RS17430 (AXW83_17435) | 3625267..3625746 | + | 480 | WP_066620695.1 | Lrp/AsnC family transcriptional regulator | - |
AXW83_RS17435 (AXW83_17440) | 3625844..3627139 | + | 1296 | WP_066615467.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
AXW83_RS17440 (AXW83_17445) | 3627148..3627522 | - | 375 | WP_066615469.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
AXW83_RS17445 (AXW83_17450) | 3627519..3627716 | - | 198 | WP_066615471.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
AXW83_RS17450 (AXW83_17455) | 3627789..3629411 | - | 1623 | WP_066615473.1 | peptide chain release factor 3 | - |
AXW83_RS27655 | 3630233..3631246 | + | 1014 | WP_210179715.1 | hypothetical protein | - |
AXW83_RS17460 (AXW83_17465) | 3631253..3632014 | - | 762 | WP_066620702.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 125 a.a. Molecular weight: 13771.14 Da Isoelectric Point: 9.8820
>T60633 WP_066615469.1 NZ_CP014301:c3627522-3627148 [Bosea sp. PAMC 26642]
VILLDASVWIDHLRRREPRLEQLLSDRRVLMHPFVVAEVALGSIARRAAMIGLLESFPQAAVATHEEVLALIEGKKLYGL
GIGYVDVHLLASARLADARLWTRDRRLRAAADLLRLSAPFDLGG
VILLDASVWIDHLRRREPRLEQLLSDRRVLMHPFVVAEVALGSIARRAAMIGLLESFPQAAVATHEEVLALIEGKKLYGL
GIGYVDVHLLASARLADARLWTRDRRLRAAADLLRLSAPFDLGG
Download Length: 375 bp
>T60633 NZ_CP014301:c3627522-3627148 [Bosea sp. PAMC 26642]
GTGATCCTGCTTGATGCCTCGGTCTGGATCGACCACCTGCGCCGTCGCGAGCCACGCCTTGAGCAACTTCTGTCCGATCG
GCGAGTGCTCATGCACCCGTTTGTCGTCGCGGAAGTGGCGCTCGGCTCGATAGCCCGCCGCGCTGCCATGATCGGGCTGC
TGGAGAGTTTCCCACAGGCGGCAGTCGCCACGCATGAGGAAGTCTTGGCGCTGATCGAGGGCAAAAAACTCTATGGTCTC
GGCATCGGCTACGTCGATGTGCATCTTCTGGCGTCGGCTCGACTTGCCGACGCTCGGCTCTGGACGCGCGATCGGCGACT
GCGCGCCGCCGCCGATCTTTTGAGGTTGTCAGCCCCCTTCGATCTCGGCGGCTGA
GTGATCCTGCTTGATGCCTCGGTCTGGATCGACCACCTGCGCCGTCGCGAGCCACGCCTTGAGCAACTTCTGTCCGATCG
GCGAGTGCTCATGCACCCGTTTGTCGTCGCGGAAGTGGCGCTCGGCTCGATAGCCCGCCGCGCTGCCATGATCGGGCTGC
TGGAGAGTTTCCCACAGGCGGCAGTCGCCACGCATGAGGAAGTCTTGGCGCTGATCGAGGGCAAAAAACTCTATGGTCTC
GGCATCGGCTACGTCGATGTGCATCTTCTGGCGTCGGCTCGACTTGCCGACGCTCGGCTCTGGACGCGCGATCGGCGACT
GCGCGCCGCCGCCGATCTTTTGAGGTTGTCAGCCCCCTTCGATCTCGGCGGCTGA
Antitoxin
Download Length: 66 a.a. Molecular weight: 7155.27 Da Isoelectric Point: 10.5916
>AT60633 WP_066615471.1 NZ_CP014301:c3627716-3627519 [Bosea sp. PAMC 26642]
MRTTVTLDDKLVEQAQFYTGITERSALLREALTALVQREAMKRAIKLGGTDPDATAAPRRRLPAA
MRTTVTLDDKLVEQAQFYTGITERSALLREALTALVQREAMKRAIKLGGTDPDATAAPRRRLPAA
Download Length: 198 bp
>AT60633 NZ_CP014301:c3627716-3627519 [Bosea sp. PAMC 26642]
ATGCGCACGACCGTGACACTGGACGACAAGCTCGTCGAACAGGCGCAGTTCTACACGGGGATCACTGAGCGCTCGGCATT
GCTGCGCGAAGCGCTGACAGCCCTGGTCCAGCGCGAAGCGATGAAGCGCGCTATCAAACTCGGCGGCACCGATCCCGACG
CGACAGCCGCACCGCGCAGGCGTCTGCCCGCAGCGTGA
ATGCGCACGACCGTGACACTGGACGACAAGCTCGTCGAACAGGCGCAGTTCTACACGGGGATCACTGAGCGCTCGGCATT
GCTGCGCGAAGCGCTGACAGCCCTGGTCCAGCGCGAAGCGATGAAGCGCGCTATCAAACTCGGCGGCACCGATCCCGACG
CGACAGCCGCACCGCGCAGGCGTCTGCCCGCAGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A126NYV3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A126NYF1 |