Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2395129..2395670 Replicon chromosome
Accession NZ_CP014301
Organism Bosea sp. PAMC 26642 strain PAMC26642

Toxin (Protein)


Gene name parE Uniprot ID A0A126NV86
Locus tag AXW83_RS11435 Protein ID WP_066613558.1
Coordinates 2395374..2395670 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A126NV77
Locus tag AXW83_RS11430 Protein ID WP_066613552.1
Coordinates 2395129..2395377 (+) Length 83 a.a.

Genomic Context

AXW83_RS11400AXW83_RS11410AXW83_RS11415AXW83_RS11430AXW83_RS11435AXW83_RS11455AXW83_RS11460AXW83_RS11405AXW83_RS11420AXW83_RS11425AXW83_RS11440AXW83_RS11445AXW83_RS11450AXW83_RS11465
Location: 2390389..2390994 (606 bp)
Type: Others
Protein ID: WP_066613542.1
Location: 2392296..2393093 (798 bp)
Type: Others
Protein ID: WP_082767073.1
Location: 2393059..2393835 (777 bp)
Type: Others
Protein ID: WP_066613547.1
Location: 2395129..2395377 (249 bp)
Type: Antitoxin
Protein ID: WP_066613552.1
Location: 2395374..2395670 (297 bp)
Type: Toxin
Protein ID: WP_066613558.1
Location: 2398685..2398924 (240 bp)
Type: Others
Protein ID: WP_066613566.1
Location: 2398921..2399340 (420 bp)
Type: Others
Protein ID: WP_066613570.1
Location: 2391219..2391923 (705 bp)
Type: Others
Protein ID: WP_066613544.1
Location: 2393846..2394475 (630 bp)
Type: Others
Protein ID: WP_066613549.1
Location: 2394650..2394934 (285 bp)
Type: Others
Protein ID: WP_066613551.1
Location: 2395676..2396440 (765 bp)
Type: Others
Protein ID: WP_066613560.1
Location: 2396491..2397639 (1149 bp)
Type: Others
Protein ID: WP_210179697.1
Location: 2397705..2398541 (837 bp)
Type: Others
Protein ID: WP_066613564.1
Location: 2399372..2399938 (567 bp)
Type: Others
Protein ID: WP_066620342.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AXW83_RS11400 (AXW83_11405)2390389..2390994+606WP_066613542.1glutathione S-transferase-
AXW83_RS11405 (AXW83_11410)2391219..2391923-705WP_066613544.1porin family protein-
AXW83_RS11410 (AXW83_11415)2392296..2393093+798WP_082767073.1glycosyltransferase family 2 protein-
AXW83_RS11415 (AXW83_11420)2393059..2393835+777WP_066613547.1SDR family oxidoreductase-
AXW83_RS11420 (AXW83_11425)2393846..2394475-630WP_066613549.12-hydroxychromene-2-carboxylate isomerase-
AXW83_RS11425 (AXW83_11430)2394650..2394934-285WP_066613551.1hypothetical protein-
AXW83_RS11430 (AXW83_11435)2395129..2395377+249WP_066613552.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
AXW83_RS11435 (AXW83_11440)2395374..2395670+297WP_066613558.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AXW83_RS11440 (AXW83_11445)2395676..2396440-765WP_066613560.1peptidoglycan editing factor PgeF-
AXW83_RS11445 (AXW83_11450)2396491..2397639-1149WP_210179697.1SAM-dependent methyltransferase-
AXW83_RS11450 (AXW83_11455)2397705..2398541-837WP_066613564.1prolipoprotein diacylglyceryl transferase-
AXW83_RS11455 (AXW83_11460)2398685..2398924+240WP_066613566.1plasmid stability protein-
AXW83_RS11460 (AXW83_11465)2398921..2399340+420WP_066613570.1type II toxin-antitoxin system VapC family toxin-
AXW83_RS11465 (AXW83_11470)2399372..2399938-567WP_066620342.1chloramphenicol phosphotransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11364.11 Da        Isoelectric Point: 11.7505

>T60630 WP_066613558.1 NZ_CP014301:2395374-2395670 [Bosea sp. PAMC 26642]
MTLRILVRPKAVADLEDIWRFSKSEWGARQADLYLESLRSAFARLADTPGSGAVFEHVRANYQRLLIGSHAIFYRVSSRQ
IDIVRVLHQRRNASRILR

Download         Length: 297 bp

>T60630 NZ_CP014301:2395374-2395670 [Bosea sp. PAMC 26642]
ATGACGCTTCGAATCCTCGTCCGGCCGAAAGCCGTGGCCGATCTCGAAGACATATGGCGCTTCTCTAAGAGCGAGTGGGG
CGCGCGGCAGGCAGACCTGTATTTGGAATCGCTACGATCAGCGTTCGCGCGTCTCGCGGATACCCCCGGCAGCGGCGCCG
TTTTCGAACATGTTCGTGCTAATTATCAACGGCTACTCATCGGGTCTCACGCCATCTTCTACAGGGTGTCCAGCCGTCAA
ATCGATATCGTCCGTGTCCTGCACCAGCGCCGCAACGCCTCGCGGATATTGCGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8939.76 Da        Isoelectric Point: 3.8563

>AT60630 WP_066613552.1 NZ_CP014301:2395129-2395377 [Bosea sp. PAMC 26642]
MGENTSISLGDHFVAFIDKQVAEGRYVSASEVVRAALQLLEENEAEIAALQAALIEGEESGDAEEFDFEAFIARMHAEHE
QG

Download         Length: 249 bp

>AT60630 NZ_CP014301:2395129-2395377 [Bosea sp. PAMC 26642]
ATGGGCGAGAACACGTCGATCAGCCTGGGCGACCATTTCGTCGCTTTCATCGACAAGCAAGTGGCCGAGGGACGTTATGT
CTCCGCAAGCGAGGTCGTCAGGGCCGCGTTGCAATTGCTGGAAGAGAATGAGGCGGAGATCGCGGCCCTGCAGGCAGCCT
TGATAGAAGGCGAAGAGAGCGGCGATGCCGAGGAGTTCGACTTCGAGGCTTTCATCGCCAGAATGCACGCCGAGCATGAA
CAGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A126NV86

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A126NV77

References