Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 95073..95758 Replicon chromosome
Accession NZ_CP014301
Organism Bosea sp. PAMC 26642 strain PAMC26642

Toxin (Protein)


Gene name vapC Uniprot ID A0A126NTR0
Locus tag AXW83_RS00455 Protein ID WP_066609692.1
Coordinates 95073..95498 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A126NQ93
Locus tag AXW83_RS00460 Protein ID WP_066609693.1
Coordinates 95495..95758 (-) Length 88 a.a.

Genomic Context

AXW83_RS00435AXW83_RS00440AXW83_RS00445AXW83_RS00450AXW83_RS00465AXW83_RS00455AXW83_RS00460AXW83_RS00470AXW83_RS00475AXW83_RS00480AXW83_RS00485AXW83_RS00490
Location: 90403..91578 (1176 bp)
Type: Others
Protein ID: WP_066609682.1
Location: 91616..91990 (375 bp)
Type: Others
Protein ID: WP_066609684.1
Location: 92151..93497 (1347 bp)
Type: Others
Protein ID: WP_066609686.1
Location: 93491..95065 (1575 bp)
Type: Others
Protein ID: WP_066609690.1
Location: 95932..97173 (1242 bp)
Type: Others
Protein ID: WP_066609698.1
Location: 95073..95498 (426 bp)
Type: Toxin
Protein ID: WP_066609692.1
Location: 95495..95758 (264 bp)
Type: Antitoxin
Protein ID: WP_066609693.1
Location: 97473..97949 (477 bp)
Type: Others
Protein ID: WP_066609699.1
Location: 97961..98560 (600 bp)
Type: Others
Protein ID: WP_082766861.1
Location: 98656..98883 (228 bp)
Type: Others
Protein ID: WP_066609701.1
Location: 98947..99708 (762 bp)
Type: Others
Protein ID: WP_066609702.1
Location: 99754..100104 (351 bp)
Type: Others
Protein ID: WP_066609703.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AXW83_RS00435 (AXW83_00435)90403..91578+1176WP_066609682.1glycine cleavage system aminomethyltransferase GcvT-
AXW83_RS00440 (AXW83_00440)91616..91990+375WP_066609684.1glycine cleavage system protein GcvH-
AXW83_RS00445 (AXW83_00445)92151..93497+1347WP_066609686.1aminomethyl-transferring glycine dehydrogenase subunit GcvPA-
AXW83_RS00450 (AXW83_00450)93491..95065+1575WP_066609690.1aminomethyl-transferring glycine dehydrogenase subunit GcvPB-
AXW83_RS00455 (AXW83_00455)95073..95498-426WP_066609692.1type II toxin-antitoxin system VapC family toxinToxin
AXW83_RS00460 (AXW83_00460)95495..95758-264WP_066609693.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
AXW83_RS00465 (AXW83_00465)95932..97173+1242WP_066609698.1L,D-transpeptidase family protein-
AXW83_RS00470 (AXW83_00470)97473..97949-477WP_066609699.1ATP F0F1 synthase subunit B-
AXW83_RS00475 (AXW83_00475)97961..98560-600WP_082766861.1hypothetical protein-
AXW83_RS00480 (AXW83_00480)98656..98883-228WP_066609701.1F0F1 ATP synthase subunit C-
AXW83_RS00485 (AXW83_00485)98947..99708-762WP_066609702.1F0F1 ATP synthase subunit A-
AXW83_RS00490 (AXW83_00490)99754..100104-351WP_066609703.1AtpZ/AtpI family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-71)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15811.16 Da        Isoelectric Point: 8.7260

>T60625 WP_066609692.1 NZ_CP014301:c95498-95073 [Bosea sp. PAMC 26642]
MTFLLDTNVVSEPQKPRPAAAVERFFRETPERNLYVSVVTTAELYRGLALMTPGHRHFALSRWITEALPRRFGGRLLPVT
VSIAARWGDIMAHSHRTGLNMSIMDGFLAATAAEHDLTLATRNVRHFADLGVPVFNPWDEA

Download         Length: 426 bp

>T60625 NZ_CP014301:c95498-95073 [Bosea sp. PAMC 26642]
ATGACGTTCCTGCTCGATACAAACGTCGTCTCGGAACCGCAGAAACCGCGTCCAGCTGCGGCAGTAGAGCGTTTTTTCCG
AGAAACGCCGGAGCGCAACCTCTATGTCAGCGTGGTCACAACCGCAGAACTTTACCGCGGACTTGCGTTGATGACACCGG
GCCATCGCCATTTCGCATTGTCGCGGTGGATTACCGAAGCGCTTCCGCGACGCTTCGGTGGACGGCTCCTGCCCGTCACG
GTTTCAATTGCCGCCCGCTGGGGCGATATCATGGCCCATTCTCACCGCACCGGGCTGAACATGTCCATCATGGACGGATT
CCTGGCGGCAACGGCGGCGGAACACGACCTCACGCTCGCTACCCGCAACGTCCGACATTTCGCTGATCTCGGCGTGCCCG
TCTTCAACCCCTGGGACGAAGCCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9796.87 Da        Isoelectric Point: 4.5386

>AT60625 WP_066609693.1 NZ_CP014301:c95758-95495 [Bosea sp. PAMC 26642]
MSAVSKETWTVASAKARFSEFIESARSDGPQIVTRNGKPAAVLVSSEDWERTASREENLFDFLRNSPLRGADLDLERLDE
KPRDLDL

Download         Length: 264 bp

>AT60625 NZ_CP014301:c95758-95495 [Bosea sp. PAMC 26642]
ATGAGCGCAGTTTCAAAGGAAACTTGGACAGTCGCCAGCGCCAAGGCTCGCTTTTCCGAGTTCATCGAGAGCGCGCGGTC
GGATGGACCGCAGATCGTAACCCGGAACGGCAAACCCGCTGCGGTTCTGGTATCGTCCGAGGACTGGGAGCGAACAGCGT
CTCGCGAGGAGAACCTGTTCGATTTCCTGCGGAATTCGCCGTTGCGTGGCGCCGATCTCGATCTGGAGCGGCTAGACGAA
AAGCCGCGCGACCTCGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A126NTR0

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A126NQ93

References