Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3831058..3831403 Replicon chromosome
Accession NZ_CP014274
Organism Stenotrophomonas sp. KCTC 12332 strain YM1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A126NMD1
Locus tag AXG53_RS16490 Protein ID WP_062170399.1
Coordinates 3831058..3831195 (-) Length 46 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A126NT85
Locus tag AXG53_RS16495 Protein ID WP_062171871.1
Coordinates 3831251..3831403 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXG53_RS16465 3826736..3827668 - 933 WP_062170389.1 MBL fold metallo-hydrolase -
AXG53_RS16470 3827754..3828047 - 294 WP_062170391.1 hypothetical protein -
AXG53_RS16475 3828070..3829371 - 1302 WP_062170393.1 tryptophan--tRNA ligase -
AXG53_RS16480 3829493..3830320 + 828 WP_062170395.1 hypothetical protein -
AXG53_RS16485 3830638..3830859 - 222 WP_062170397.1 CsbD family protein -
AXG53_RS16490 3831058..3831195 - 138 WP_062170399.1 entericidin A/B family lipoprotein Toxin
AXG53_RS16495 3831251..3831403 - 153 WP_062171871.1 entericidin A/B family lipoprotein Antitoxin
AXG53_RS16500 3831543..3832463 - 921 WP_062170401.1 arginase -
AXG53_RS16505 3832662..3834305 - 1644 WP_065868108.1 mechanosensitive ion channel family protein -
AXG53_RS16510 3834964..3835395 + 432 WP_062170404.1 CBS domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 4556.42 Da        Isoelectric Point: 10.2067

>T60616 WP_062170399.1 NZ_CP014274:c3831195-3831058 [Stenotrophomonas sp. KCTC 12332]
MKRLVALMLLSLFSVAVLSGCNTVAGAGKDVQKAGEKVEGAAKGH

Download         Length: 138 bp

>T60616 NZ_CP014274:c3831195-3831058 [Stenotrophomonas sp. KCTC 12332]
ATGAAGCGTTTGGTCGCCCTGATGTTGTTGTCGCTGTTTTCGGTTGCGGTGCTGTCTGGCTGCAATACCGTGGCCGGTGC
CGGCAAGGATGTGCAGAAGGCTGGTGAGAAGGTTGAGGGTGCTGCCAAGGGTCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5209.17 Da        Isoelectric Point: 8.2766

>AT60616 WP_062171871.1 NZ_CP014274:c3831403-3831251 [Stenotrophomonas sp. KCTC 12332]
MKRVMMLALVGAFSVGMLSGCNTVAGAGKDMQKAGEKVEDKAQDCKDGKC

Download         Length: 153 bp

>AT60616 NZ_CP014274:c3831403-3831251 [Stenotrophomonas sp. KCTC 12332]
ATGAAGCGAGTGATGATGTTGGCCCTGGTGGGCGCGTTCTCGGTTGGCATGCTCAGCGGCTGCAATACCGTCGCCGGCGC
CGGCAAGGACATGCAGAAGGCCGGTGAGAAGGTCGAAGACAAGGCCCAGGATTGTAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A126NMD1

Antitoxin

Source ID Structure
AlphaFold DB A0A126NT85

References