60580

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2028181..2028452 Replicon chromosome
Accession NZ_CP014272
Organism Escherichia coli K-12 strain K-12 C3026

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2028219..2028322 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2028181..2028452 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3026_RS10430 2025338..2026777 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C3026_RS10435 2026895..2027131 + 237 WP_001295499.1 DUF1480 family protein -
C3026_RS10440 2027236..2027427 + 192 WP_000457842.1 YebW family protein -
C3026_RS10445 2027428..2028084 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2028181..2028452 + 272 - - Antitoxin
- 2028219..2028322 - 104 - - Toxin
C3026_RS10455 2028480..2028821 - 342 WP_000976476.1 YebY family protein -
C3026_RS10460 2028834..2029706 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
C3026_RS10465 2029710..2030084 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C3026_RS10470 2030223..2030453 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C3026_RS10475 2030555..2031211 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C3026_RS10480 2031235..2031897 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T60580 NZ_CP014272:c2028322-2028219 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT60580 NZ_CP014272:2028181-2028452 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References