Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1829113..1829384 Replicon chromosome
Accession NZ_CP014270
Organism Escherichia coli K-12 strain K-12 DHB4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1829151..1829254 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1829113..1829384 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DHB4_RS09205 1826270..1827709 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DHB4_RS09210 1827827..1828063 + 237 WP_001295499.1 DUF1480 family protein -
DHB4_RS09215 1828168..1828359 + 192 WP_000457842.1 YebW family protein -
DHB4_RS09220 1828360..1829016 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1829113..1829384 + 272 - - Antitoxin
- 1829151..1829254 - 104 - - Toxin
DHB4_RS09230 1829412..1829753 - 342 WP_000976476.1 YebY family protein -
DHB4_RS09235 1829766..1830638 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
DHB4_RS09240 1830642..1831016 - 375 WP_000168747.1 CopC domain-containing protein YobA -
DHB4_RS09245 1831155..1831385 + 231 WP_000916763.1 DNA polymerase III subunit theta -
DHB4_RS09250 1831487..1832143 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DHB4_RS09255 1832167..1832829 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T60528 NZ_CP014270:c1829254-1829151 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT60528 NZ_CP014270:1829113-1829384 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References