Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2613094..2613713 Replicon chromosome
Accession NZ_CP014263
Organism Spirosoma montaniterrae strain DY10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AWR27_RS11395 Protein ID WP_077131290.1
Coordinates 2613094..2613495 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AWR27_RS11400 Protein ID WP_077131291.1
Coordinates 2613492..2613713 (-) Length 74 a.a.

Genomic Context


AWR27_RS11390AWR27_RS11415AWR27_RS11385AWR27_RS11395AWR27_RS11400AWR27_RS11405AWR27_RS11410
Location: 2610698..2613091 (2394 bp)
Type: Others
Protein ID: WP_077131289.1
Location: 2615955..2617640 (1686 bp)
Type: Others
Protein ID: WP_077131294.1
Location: 2609409..2610596 (1188 bp)
Type: Others
Protein ID: WP_077131288.1
Location: 2613094..2613495 (402 bp)
Type: Toxin
Protein ID: WP_077131290.1
Location: 2613492..2613713 (222 bp)
Type: Antitoxin
Protein ID: WP_077131291.1
Location: 2613755..2614960 (1206 bp)
Type: Others
Protein ID: WP_077131292.1
Location: 2614947..2615927 (981 bp)
Type: Others
Protein ID: WP_077131293.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AWR27_RS113852609409..2610596-1188WP_077131288.1phosphoglycerate kinase-
AWR27_RS113902610698..2613091+2394WP_077131289.1M20/M25/M40 family metallo-hydrolase-
AWR27_RS113952613094..2613495-402WP_077131290.1PIN domain nucleaseToxin
AWR27_RS114002613492..2613713-222WP_077131291.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
AWR27_RS114052613755..2614960-1206WP_077131292.1hypothetical protein-
AWR27_RS114102614947..2615927-981WP_077131293.1DUF2157 domain-containing protein-
AWR27_RS114152615955..2617640+1686WP_077131294.1VRR-NUC domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-126)

Antitoxin

(1-43)


Sequences


Toxin        


Download         Length: 134 a.a.        Molecular weight: 15058.51 Da        Isoelectric Point: 8.7346

>T60454 WP_077131290.1 NZ_CP014263:c2613495-2613094 [Spirosoma montaniterrae]
MTEPIIVDTSVWIDCFRGISTNQTKIVIDRLLTPGLIAITPTILQETLQGFREDNEWQRARTNLLACKILRADAIKAAIG
AAQLYRSLRKKGVTIRKPNDCLIAHYALFYDLPILHNDADFDQIARHTTLRVA

Download         Length: 402 bp

>T60454 NZ_CP014263:c2613495-2613094 [Spirosoma montaniterrae]
ATGACAGAGCCAATTATTGTTGACACGTCGGTTTGGATTGACTGTTTCCGGGGAATTAGCACTAACCAGACAAAGATTGT
TATCGACCGATTGCTCACGCCTGGATTGATTGCAATTACGCCGACTATTTTGCAGGAAACTTTGCAGGGGTTTCGGGAGG
ATAACGAATGGCAACGGGCCAGAACCAATCTGCTGGCTTGTAAAATTCTTCGTGCGGATGCTATAAAAGCCGCAATAGGA
GCAGCTCAGTTATACCGCTCCCTCCGCAAAAAAGGCGTTACTATCCGCAAACCAAACGACTGCCTGATTGCCCATTACGC
CCTTTTCTACGACCTGCCTATTCTACACAATGACGCTGACTTCGACCAAATCGCCCGGCACACTACCTTGCGCGTGGCGT
AA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8761.06 Da        Isoelectric Point: 4.5112

>AT60454 WP_077131291.1 NZ_CP014263:c2613713-2613492 [Spirosoma montaniterrae]
MRTNIDINDELLQEIMELTRIKTKREAVNLALDEFLKTLRRRDLLAMFGNVTWEGDLEQMRTVVRPEEWDDKP

Download         Length: 222 bp

>AT60454 NZ_CP014263:c2613713-2613492 [Spirosoma montaniterrae]
ATGCGAACGAACATTGACATCAATGATGAACTGTTGCAGGAAATCATGGAGCTTACCCGCATCAAAACCAAACGCGAAGC
TGTTAATCTGGCCCTCGATGAATTTTTGAAAACGTTGCGTCGTAGGGATCTGCTTGCTATGTTTGGTAACGTTACCTGGG
AAGGTGACCTCGAACAAATGCGTACAGTTGTGCGTCCTGAAGAGTGGGATGACAAACCATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References