Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VapB |
Location | 2613094..2613713 | Replicon | chromosome |
Accession | NZ_CP014263 | ||
Organism | Spirosoma montaniterrae strain DY10 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | AWR27_RS11395 | Protein ID | WP_077131290.1 |
Coordinates | 2613094..2613495 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | AWR27_RS11400 | Protein ID | WP_077131291.1 |
Coordinates | 2613492..2613713 (-) | Length | 74 a.a. |
Genomic Context
Location: 2610698..2613091 (2394 bp)
Type: Others
Protein ID: WP_077131289.1
Type: Others
Protein ID: WP_077131289.1
Location: 2615955..2617640 (1686 bp)
Type: Others
Protein ID: WP_077131294.1
Type: Others
Protein ID: WP_077131294.1
Location: 2609409..2610596 (1188 bp)
Type: Others
Protein ID: WP_077131288.1
Type: Others
Protein ID: WP_077131288.1
Location: 2613094..2613495 (402 bp)
Type: Toxin
Protein ID: WP_077131290.1
Type: Toxin
Protein ID: WP_077131290.1
Location: 2613492..2613713 (222 bp)
Type: Antitoxin
Protein ID: WP_077131291.1
Type: Antitoxin
Protein ID: WP_077131291.1
Location: 2613755..2614960 (1206 bp)
Type: Others
Protein ID: WP_077131292.1
Type: Others
Protein ID: WP_077131292.1
Location: 2614947..2615927 (981 bp)
Type: Others
Protein ID: WP_077131293.1
Type: Others
Protein ID: WP_077131293.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AWR27_RS11385 | 2609409..2610596 | - | 1188 | WP_077131288.1 | phosphoglycerate kinase | - |
AWR27_RS11390 | 2610698..2613091 | + | 2394 | WP_077131289.1 | M20/M25/M40 family metallo-hydrolase | - |
AWR27_RS11395 | 2613094..2613495 | - | 402 | WP_077131290.1 | PIN domain nuclease | Toxin |
AWR27_RS11400 | 2613492..2613713 | - | 222 | WP_077131291.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
AWR27_RS11405 | 2613755..2614960 | - | 1206 | WP_077131292.1 | hypothetical protein | - |
AWR27_RS11410 | 2614947..2615927 | - | 981 | WP_077131293.1 | DUF2157 domain-containing protein | - |
AWR27_RS11415 | 2615955..2617640 | + | 1686 | WP_077131294.1 | VRR-NUC domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15058.51 Da Isoelectric Point: 8.7346
>T60454 WP_077131290.1 NZ_CP014263:c2613495-2613094 [Spirosoma montaniterrae]
MTEPIIVDTSVWIDCFRGISTNQTKIVIDRLLTPGLIAITPTILQETLQGFREDNEWQRARTNLLACKILRADAIKAAIG
AAQLYRSLRKKGVTIRKPNDCLIAHYALFYDLPILHNDADFDQIARHTTLRVA
MTEPIIVDTSVWIDCFRGISTNQTKIVIDRLLTPGLIAITPTILQETLQGFREDNEWQRARTNLLACKILRADAIKAAIG
AAQLYRSLRKKGVTIRKPNDCLIAHYALFYDLPILHNDADFDQIARHTTLRVA
Download Length: 402 bp
>T60454 NZ_CP014263:c2613495-2613094 [Spirosoma montaniterrae]
ATGACAGAGCCAATTATTGTTGACACGTCGGTTTGGATTGACTGTTTCCGGGGAATTAGCACTAACCAGACAAAGATTGT
TATCGACCGATTGCTCACGCCTGGATTGATTGCAATTACGCCGACTATTTTGCAGGAAACTTTGCAGGGGTTTCGGGAGG
ATAACGAATGGCAACGGGCCAGAACCAATCTGCTGGCTTGTAAAATTCTTCGTGCGGATGCTATAAAAGCCGCAATAGGA
GCAGCTCAGTTATACCGCTCCCTCCGCAAAAAAGGCGTTACTATCCGCAAACCAAACGACTGCCTGATTGCCCATTACGC
CCTTTTCTACGACCTGCCTATTCTACACAATGACGCTGACTTCGACCAAATCGCCCGGCACACTACCTTGCGCGTGGCGT
AA
ATGACAGAGCCAATTATTGTTGACACGTCGGTTTGGATTGACTGTTTCCGGGGAATTAGCACTAACCAGACAAAGATTGT
TATCGACCGATTGCTCACGCCTGGATTGATTGCAATTACGCCGACTATTTTGCAGGAAACTTTGCAGGGGTTTCGGGAGG
ATAACGAATGGCAACGGGCCAGAACCAATCTGCTGGCTTGTAAAATTCTTCGTGCGGATGCTATAAAAGCCGCAATAGGA
GCAGCTCAGTTATACCGCTCCCTCCGCAAAAAAGGCGTTACTATCCGCAAACCAAACGACTGCCTGATTGCCCATTACGC
CCTTTTCTACGACCTGCCTATTCTACACAATGACGCTGACTTCGACCAAATCGCCCGGCACACTACCTTGCGCGTGGCGT
AA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8761.06 Da Isoelectric Point: 4.5112
>AT60454 WP_077131291.1 NZ_CP014263:c2613713-2613492 [Spirosoma montaniterrae]
MRTNIDINDELLQEIMELTRIKTKREAVNLALDEFLKTLRRRDLLAMFGNVTWEGDLEQMRTVVRPEEWDDKP
MRTNIDINDELLQEIMELTRIKTKREAVNLALDEFLKTLRRRDLLAMFGNVTWEGDLEQMRTVVRPEEWDDKP
Download Length: 222 bp
>AT60454 NZ_CP014263:c2613713-2613492 [Spirosoma montaniterrae]
ATGCGAACGAACATTGACATCAATGATGAACTGTTGCAGGAAATCATGGAGCTTACCCGCATCAAAACCAAACGCGAAGC
TGTTAATCTGGCCCTCGATGAATTTTTGAAAACGTTGCGTCGTAGGGATCTGCTTGCTATGTTTGGTAACGTTACCTGGG
AAGGTGACCTCGAACAAATGCGTACAGTTGTGCGTCCTGAAGAGTGGGATGACAAACCATGA
ATGCGAACGAACATTGACATCAATGATGAACTGTTGCAGGAAATCATGGAGCTTACCCGCATCAAAACCAAACGCGAAGC
TGTTAATCTGGCCCTCGATGAATTTTTGAAAACGTTGCGTCGTAGGGATCTGCTTGCTATGTTTGGTAACGTTACCTGGG
AAGGTGACCTCGAACAAATGCGTACAGTTGTGCGTCCTGAAGAGTGGGATGACAAACCATGA