Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 3093844..3094364 Replicon chromosome
Accession NZ_CP014229
Organism Desulfovibrio fairfieldensis strain CCUG 45958

Toxin (Protein)


Gene name relB Uniprot ID A0A0X8JLH5
Locus tag AXF13_RS13035 Protein ID WP_062253882.1
Coordinates 3093844..3094104 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A109W4U4
Locus tag AXF13_RS13040 Protein ID WP_062253884.1
Coordinates 3094107..3094364 (-) Length 86 a.a.

Genomic Context

AXF13_RS13030AXF13_RS16875AXF13_RS16880AXF13_RS16885AXF13_RS13035AXF13_RS13040
Location: 3090145..3091326 (1182 bp)
Type: Others
Protein ID: WP_062253881.1
Location: 3091670..3092158 (489 bp)
Type: Others
Protein ID: WP_150116179.1
Location: 3092162..3092698 (537 bp)
Type: Others
Protein ID: WP_150116180.1
Location: 3092700..3093458 (759 bp)
Type: Others
Protein ID: WP_150116181.1
Location: 3093844..3094104 (261 bp)
Type: Toxin
Protein ID: WP_062253882.1
Location: 3094107..3094364 (258 bp)
Type: Antitoxin
Protein ID: WP_062253884.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AXF13_RS130303090145..3091326-1182WP_062253881.1aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme-
AXF13_RS168753091670..3092158-489WP_150116179.1hypothetical protein-
AXF13_RS168803092162..3092698-537WP_150116180.1hypothetical protein-
AXF13_RS168853092700..3093458-759WP_150116181.1hypothetical protein-
AXF13_RS130353093844..3094104-261WP_062253882.1Txe/YoeB family addiction module toxinToxin
AXF13_RS130403094107..3094364-258WP_062253884.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-69)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10152.73 Da        Isoelectric Point: 9.0362

>T60424 WP_062253882.1 NZ_CP014229:c3094104-3093844 [Desulfovibrio fairfieldensis]
VLLAWTPQAWEDYLYWQGTDKKILKRINALLRDALRDFGSGLGKPEALKFDLNGCWSRRIDLAHRLVYRVDEPAGQFIVL
QCRYHY

Download         Length: 261 bp

>T60424 NZ_CP014229:c3094104-3093844 [Desulfovibrio fairfieldensis]
GTGCTGCTTGCCTGGACGCCGCAAGCCTGGGAGGATTACCTCTACTGGCAAGGTACGGACAAAAAAATCCTCAAACGTAT
CAACGCGCTTCTCCGTGACGCCCTGCGCGACTTCGGTTCTGGACTGGGCAAACCGGAAGCGTTGAAATTCGATCTCAACG
GCTGCTGGTCACGCCGGATTGATCTCGCCCACCGCCTCGTCTATCGAGTGGATGAGCCCGCCGGACAGTTCATTGTGCTG
CAATGCCGTTATCACTACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9440.71 Da        Isoelectric Point: 6.9773

>AT60424 WP_062253884.1 NZ_CP014229:c3094364-3094107 [Desulfovibrio fairfieldensis]
MSQAITYSEARQNLAETMNRVCDTHTPLIITRRKSQPVVMLSLEDYSSLAETSYLLQSPANAERLRAALSAAAKGETTLR
RLEEA

Download         Length: 258 bp

>AT60424 NZ_CP014229:c3094364-3094107 [Desulfovibrio fairfieldensis]
ATGAGCCAGGCCATTACCTATTCCGAGGCCCGTCAGAATCTGGCGGAAACCATGAATCGCGTATGCGACACGCATACGCC
CCTGATCATCACCCGACGCAAGTCCCAACCAGTGGTCATGCTTTCGCTGGAGGACTACAGCAGTCTGGCTGAAACCTCCT
ATCTGCTGCAAAGTCCCGCCAATGCCGAGCGGTTGCGGGCGGCCCTAAGCGCCGCGGCCAAGGGGGAAACCACGCTTCGC
CGGCTTGAGGAGGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0X8JLH5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A109W4U4

References