Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1111157..1111664 Replicon chromosome
Accession NZ_CP014229
Organism Desulfovibrio fairfieldensis strain CCUG 45958

Toxin (Protein)


Gene name - Uniprot ID A0A0X8JIK7
Locus tag AXF13_RS04785 Protein ID WP_062251853.1
Coordinates 1111401..1111664 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A109W3Y1
Locus tag AXF13_RS04780 Protein ID WP_062251852.1
Coordinates 1111157..1111414 (-) Length 86 a.a.

Genomic Context

AXF13_RS04790AXF13_RS04795AXF13_RS04800AXF13_RS04805AXF13_RS04810AXF13_RS04815AXF13_RS04820AXF13_RS04765AXF13_RS04770AXF13_RS15795AXF13_RS04775AXF13_RS04780AXF13_RS04785
Location: 1111945..1112706 (762 bp)
Type: Others
Protein ID: WP_062251854.1
Location: 1112719..1113849 (1131 bp)
Type: Others
Protein ID: WP_062251855.1
Location: 1113863..1114162 (300 bp)
Type: Others
Protein ID: WP_062251856.1
Location: 1114299..1114877 (579 bp)
Type: Others
Protein ID: WP_062251857.1
Location: 1114880..1115254 (375 bp)
Type: Others
Protein ID: WP_062251858.1
Location: 1115251..1115676 (426 bp)
Type: Others
Protein ID: WP_062251859.1
Location: 1115673..1116095 (423 bp)
Type: Others
Protein ID: WP_062251860.1
Location: 1106602..1107924 (1323 bp)
Type: Others
Protein ID: WP_062251849.1
Location: 1108049..1109173 (1125 bp)
Type: Others
Protein ID: WP_062251850.1
Location: 1109742..1110557 (816 bp)
Type: Others
Protein ID: WP_083521957.1
Location: 1110554..1111051 (498 bp)
Type: Others
Protein ID: WP_062251851.1
Location: 1111157..1111414 (258 bp)
Type: Antitoxin
Protein ID: WP_062251852.1
Location: 1111401..1111664 (264 bp)
Type: Toxin
Protein ID: WP_062251853.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AXF13_RS047651106602..1107924-1323WP_062251849.1hypothetical protein-
AXF13_RS047701108049..1109173-1125WP_062251850.1DUF932 domain-containing protein-
AXF13_RS157951109742..1110557-816WP_083521957.1hypothetical protein-
AXF13_RS047751110554..1111051-498WP_062251851.1DUF2846 domain-containing protein-
AXF13_RS047801111157..1111414-258WP_062251852.1hypothetical proteinAntitoxin
AXF13_RS047851111401..1111664-264WP_062251853.1BrnT family toxinToxin
AXF13_RS047901111945..1112706+762WP_062251854.1hypothetical protein-
AXF13_RS047951112719..1113849+1131WP_062251855.1hypothetical protein-
AXF13_RS048001113863..1114162+300WP_062251856.1SAP domain-containing protein-
AXF13_RS048051114299..1114877+579WP_062251857.1hypothetical protein-
AXF13_RS048101114880..1115254+375WP_062251858.1hypothetical protein-
AXF13_RS048151115251..1115676+426WP_062251859.1hypothetical protein-
AXF13_RS048201115673..1116095+423WP_062251860.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1067785..113348465699


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10227.60 Da        Isoelectric Point: 6.2268

>T60422 WP_062251853.1 NZ_CP014229:c1111664-1111401 [Desulfovibrio fairfieldensis]
MQYEYDPNKSAANKLKHGLDFDEAKALWDDDNALMLRVDRPGEERHIVIGHMFGTYWTAVITFRGENIRIISVRRARKEE
VMLYEQG

Download         Length: 264 bp

>T60422 NZ_CP014229:c1111664-1111401 [Desulfovibrio fairfieldensis]
ATGCAGTACGAATATGACCCCAACAAAAGCGCTGCCAATAAGCTCAAGCACGGTCTCGATTTCGATGAGGCCAAGGCCCT
GTGGGATGACGATAATGCGTTGATGCTTCGAGTGGACAGGCCGGGTGAAGAACGTCATATCGTAATCGGCCATATGTTCG
GTACTTACTGGACAGCAGTTATTACGTTCAGGGGCGAGAATATTCGTATCATTTCAGTGCGCCGCGCCCGTAAAGAAGAG
GTCATGCTTTATGAACAAGGATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9759.07 Da        Isoelectric Point: 4.8538

>AT60422 WP_062251852.1 NZ_CP014229:c1111414-1111157 [Desulfovibrio fairfieldensis]
MNKDKKNVSAEEFDRIFDEGKEDITPYLDLDSATRINKRAKRVNVDFPAWMVEAMDQEADRIGITRQAFIKVVIAERLGS
LTQQA

Download         Length: 258 bp

>AT60422 NZ_CP014229:c1111414-1111157 [Desulfovibrio fairfieldensis]
ATGAACAAGGATAAAAAAAATGTTTCAGCCGAGGAGTTTGACCGCATTTTTGACGAAGGCAAAGAGGACATTACCCCTTA
CCTTGATCTTGACTCGGCAACGCGTATCAACAAGAGAGCTAAACGCGTCAATGTGGACTTTCCCGCATGGATGGTTGAGG
CTATGGATCAGGAGGCCGACCGCATAGGCATTACCCGCCAGGCATTTATTAAAGTGGTGATTGCTGAACGCTTGGGATCT
CTCACGCAACAAGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0X8JIK7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A109W3Y1

References