Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 268736..269343 Replicon chromosome
Accession NZ_CP014229
Organism Desulfovibrio fairfieldensis strain CCUG 45958

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag AXF13_RS15670 Protein ID WP_083521910.1
Coordinates 268736..269038 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0X8JHC1
Locus tag AXF13_RS01185 Protein ID WP_062251331.1
Coordinates 269035..269343 (+) Length 103 a.a.

Genomic Context

AXF13_RS01175AXF13_RS16360AXF13_RS15665AXF13_RS15670AXF13_RS01185AXF13_RS01160AXF13_RS01165AXF13_RS01170
Location: 267588..267812 (225 bp)
Type: Others
Protein ID: WP_062251329.1
Location: 267920..268246 (327 bp)
Type: Others
Protein ID: WP_150116045.1
Location: 268337..268705 (369 bp)
Type: Others
Protein ID: WP_083521909.1
Location: 268736..269038 (303 bp)
Type: Toxin
Protein ID: WP_083521910.1
Location: 269035..269343 (309 bp)
Type: Antitoxin
Protein ID: WP_062251331.1
Location: 265770..266492 (723 bp)
Type: Others
Protein ID: WP_062251326.1
Location: 266504..267004 (501 bp)
Type: Others
Protein ID: WP_062251327.1
Location: 267069..267431 (363 bp)
Type: Others
Protein ID: WP_062251328.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AXF13_RS01160265770..266492-723WP_062251326.1hypothetical protein-
AXF13_RS01165266504..267004-501WP_062251327.1hypothetical protein-
AXF13_RS01170267069..267431-363WP_062251328.1hypothetical protein-
AXF13_RS01175267588..267812+225WP_062251329.1helix-turn-helix transcriptional regulator-
AXF13_RS16360267920..268246+327WP_150116045.1hypothetical protein-
AXF13_RS15665268337..268705+369WP_083521909.1Bro-N domain-containing protein-
AXF13_RS15670268736..269038+303WP_083521910.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AXF13_RS01185269035..269343+309WP_062251331.1putative addiction module antidote proteinAntitoxin

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11327.25 Da        Isoelectric Point: 10.2954

>T60421 WP_083521910.1 NZ_CP014229:268736-269038 [Desulfovibrio fairfieldensis]
MNTIIKSELFDSWLTALKDTRAKFNILARLRRAEIGNFGDCRPVGDGISEMRIHIGKGYRIYFVQEGVCVYVLIVGGDKS
TQQKDIVKAKALAKERRLQP

Download         Length: 303 bp

>T60421 NZ_CP014229:268736-269038 [Desulfovibrio fairfieldensis]
ATGAACACAATTATCAAATCTGAATTATTCGATAGTTGGTTGACGGCGCTAAAGGATACGCGCGCCAAGTTCAACATTCT
GGCCAGATTGCGCCGGGCTGAGATTGGAAATTTTGGAGATTGTAGGCCTGTGGGAGATGGTATCTCTGAGATGCGAATAC
ATATTGGCAAGGGATATCGAATATATTTTGTGCAAGAAGGTGTTTGTGTTTATGTTTTGATCGTTGGCGGTGATAAATCA
ACACAGCAAAAGGATATCGTCAAAGCTAAAGCACTGGCAAAAGAGAGACGGTTACAGCCATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11292.00 Da        Isoelectric Point: 5.1726

>AT60421 WP_062251331.1 NZ_CP014229:269035-269343 [Desulfovibrio fairfieldensis]
MKYSKFDVVDYLDSEESIAEYLSAVMEERDPDLVIAALSDIAKARGMAKLAEDSGLNRESLYKALRPGSKPRYETIAKIM
GALNVKLQAVPIKQQQQSGTLL

Download         Length: 309 bp

>AT60421 NZ_CP014229:269035-269343 [Desulfovibrio fairfieldensis]
ATGAAATATTCTAAGTTTGACGTTGTGGATTATCTAGACAGTGAAGAATCCATTGCTGAATATCTTTCAGCAGTTATGGA
GGAGCGTGACCCTGATCTTGTCATTGCCGCACTCTCGGATATTGCTAAAGCGCGTGGCATGGCAAAGCTGGCGGAAGATT
CCGGCCTGAACAGGGAAAGTTTGTATAAGGCTCTACGCCCCGGTTCAAAGCCTCGTTATGAGACGATTGCTAAAATCATG
GGGGCGTTGAACGTAAAATTGCAGGCGGTGCCCATAAAACAGCAACAACAATCCGGTACACTCTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0X8JHC1

References