Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1348684..1349206 Replicon chromosome
Accession NZ_CP014223
Organism Anaerotignum propionicum DSM 1682 strain X2

Toxin (Protein)


Gene name relE Uniprot ID A0A0X1U7J8
Locus tag CPRO_RS06375 Protein ID WP_066049271.1
Coordinates 1348943..1349206 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0X1U7J4
Locus tag CPRO_RS06370 Protein ID WP_066049268.1
Coordinates 1348684..1348950 (+) Length 89 a.a.

Genomic Context

CPRO_RS15560CPRO_RS06350CPRO_RS06355CPRO_RS06365CPRO_RS06370CPRO_RS06375CPRO_RS06385CPRO_RS06390CPRO_RS06340CPRO_RS06345CPRO_RS06360CPRO_RS06380
Location: 1344874..1345011 (138 bp)
Type: Others
Protein ID: WP_200777669.1
Location: 1345978..1346400 (423 bp)
Type: Others
Protein ID: WP_066049257.1
Location: 1346415..1346870 (456 bp)
Type: Others
Protein ID: WP_066049260.1
Location: 1347791..1347973 (183 bp)
Type: Others
Protein ID: WP_066049265.1
Location: 1348684..1348950 (267 bp)
Type: Antitoxin
Protein ID: WP_066049268.1
Location: 1348943..1349206 (264 bp)
Type: Toxin
Protein ID: WP_066049271.1
Location: 1351268..1352212 (945 bp)
Type: Others
Protein ID: WP_066049277.1
Location: 1352327..1352728 (402 bp)
Type: Others
Protein ID: WP_066049281.1
Location: 1343838..1344083 (246 bp)
Type: Others
Protein ID: WP_066049252.1
Location: 1345194..1345883 (690 bp)
Type: Others
Protein ID: WP_066049255.1
Location: 1347193..1347666 (474 bp)
Type: Others
Protein ID: WP_066049262.1
Location: 1349859..1350425 (567 bp)
Type: Others
Protein ID: WP_066049274.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CPRO_RS063401343838..1344083-246WP_066049252.1helix-turn-helix domain-containing protein-
CPRO_RS155601344874..1345011+138WP_200777669.1hypothetical protein-
CPRO_RS063451345194..1345883-690WP_066049255.1cyclic nucleotide-binding domain-containing protein-
CPRO_RS063501345978..1346400+423WP_066049257.1DMT family transporter-
CPRO_RS063551346415..1346870+456WP_066049260.1DMT family transporter-
CPRO_RS063601347193..1347666-474WP_066049262.1DUF1273 family protein-
CPRO_RS063651347791..1347973+183WP_066049265.1hypothetical protein-
CPRO_RS063701348684..1348950+267WP_066049268.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
CPRO_RS063751348943..1349206+264WP_066049271.1Txe/YoeB family addiction module toxinToxin
CPRO_RS063801349859..1350425-567WP_066049274.1recombinase family protein-
CPRO_RS063851351268..1352212+945WP_066049277.1DUF2971 domain-containing protein-
CPRO_RS063901352327..1352728+402WP_066049281.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10444.84 Da        Isoelectric Point: 9.2698

>T60371 WP_066049271.1 NZ_CP014223:1348943-1349206 [Anaerotignum propionicum DSM 1682]
MNKVFTENGWKDYEYWQTEDRKTLKKINLLLQDIERNGNIGIGKPEPLTGNLSGYWSRRVSDKDRLIYRIDDKNIYILAC
RYHYGDK

Download         Length: 264 bp

>T60371 NZ_CP014223:1348943-1349206 [Anaerotignum propionicum DSM 1682]
ATGAATAAGGTATTTACTGAAAACGGGTGGAAGGACTATGAGTATTGGCAAACGGAGGATAGAAAAACTTTAAAGAAAAT
AAATCTTCTTTTGCAGGATATTGAGAGAAATGGAAATATTGGCATAGGTAAGCCTGAACCATTGACAGGTAATTTATCAG
GGTATTGGAGTAGAAGAGTCAGTGATAAGGATAGGCTGATTTATAGAATTGATGATAAGAATATTTATATATTGGCTTGT
AGGTATCACTACGGAGATAAATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10469.69 Da        Isoelectric Point: 4.2392

>AT60371 WP_066049268.1 NZ_CP014223:1348684-1348950 [Anaerotignum propionicum DSM 1682]
MLAVNYTNLRENMKAYMDKVTDDYETMIVTRKDNKNVVMISEEAYNNLIENIYVMDNKHNYDWLMESKAQLENGNTKTHE
LVEVNEDE

Download         Length: 267 bp

>AT60371 NZ_CP014223:1348684-1348950 [Anaerotignum propionicum DSM 1682]
ATGTTGGCTGTCAACTATACTAACTTAAGGGAAAACATGAAAGCATATATGGATAAGGTGACAGATGATTATGAAACTAT
GATTGTCACTAGAAAGGATAACAAGAATGTGGTCATGATTTCTGAAGAAGCTTATAATAATTTAATTGAAAACATTTATG
TTATGGATAATAAACATAACTATGATTGGTTGATGGAGTCAAAAGCTCAACTTGAAAATGGTAATACTAAAACTCATGAG
CTGGTTGAGGTAAATGAGGATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0X1U7J8

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0X1U7J4

References