Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 3413566..3414301 Replicon chromosome
Accession NZ_CP014207
Organism Pantoea ananatis strain R100

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AW734_RS15960 Protein ID WP_064373924.1
Coordinates 3413909..3414301 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AW734_RS15955 Protein ID WP_014605595.1
Coordinates 3413566..3413919 (-) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AW734_RS15920 3409863..3410549 + 687 WP_013026113.1 two-component system response regulator PmrA -
AW734_RS15925 3410546..3411613 + 1068 WP_015700151.1 two-component system sensor histidine kinase PmrB -
AW734_RS15930 3411976..3412515 + 540 WP_015700149.1 peptide-methionine (S)-S-oxide reductase MsrA -
AW734_RS15955 3413566..3413919 - 354 WP_014605595.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
AW734_RS15960 3413909..3414301 - 393 WP_064373924.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AW734_RS15965 3414626..3415573 - 948 WP_015700094.1 sulfonate ABC transporter substrate-binding protein -
AW734_RS15970 3415668..3417554 - 1887 WP_015700093.1 aliphatic sulfonate ABC transporter substrate-binding protein -
AW734_RS23140 3417575..3417727 + 153 WP_155644231.1 hypothetical protein -
AW734_RS15975 3417829..3419001 + 1173 WP_013026120.1 FMNH2-dependent alkanesulfonate monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(6-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-99)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14981.30 Da        Isoelectric Point: 10.1741

>T60356 WP_064373924.1 NZ_CP014207:c3414301-3413909 [Pantoea ananatis]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVFTGVFEADLGGGVIKKRLALHQGKRGGVRTVILFRQGTNLVYYDGWVK
NLSRKYAREIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T60356 NZ_CP014207:c3414301-3413909 [Pantoea ananatis]
ATGGGTTTTACGCTTTATGTTCATAAACGTTTTGACAGAGTGTTTAAAAAAACGCGTCTGACAGACAGCGTCCTGTGTTA
CGCAGCAGGTGACGTTTTTACTGGCGTGTTTGAGGCTGACTTAGGCGGTGGCGTTATTAAAAAGCGCCTTGCTCTTCACC
AAGGCAAGCGTGGCGGCGTGCGAACGGTCATCTTATTCAGACAAGGCACCAACCTGGTTTATTACGATGGATGGGTTAAA
AACTTGTCGAGGAAATACGCCAGGGAAATCGATGAAGATCAGCTGGATACCTACAGGGATGTGGCAAGAATGTTTTTCCG
TGCAAATAGTGAAGTGATGAGCCTGCTCGTCAGAAGCGGAATGGTCAGAGAGGTTAAATGTAATGAAAACTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13096.14 Da        Isoelectric Point: 7.2076

>AT60356 WP_014605595.1 NZ_CP014207:c3413919-3413566 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Download         Length: 354 bp

>AT60356 NZ_CP014207:c3413919-3413566 [Pantoea ananatis]
ATGAAAACTGAACCCGCCGAATTGAGTGAACTACTTGAAGATGCGAAAGCGTTTCACGCGTTAGGACTGGCAACAGATGA
AGAAGTGGAGTCCATAGCAAAGCGCGCAAAAAATCGTGAACTCCGTGCCCGTATTGCATCAGTAAAGCCCATGACAGCAA
CTGAAATCAAAGACGTGCGCATGCGTTGGGGAATGTCGCAATCGCTTGTGGCGCTCTCATTTGGCATGACGGTCGATAGC
GTATCGAAATGGGAGCGAGGTGAAATCACACCGAGCCCACCGGTGATGCGGATGCTACAACTCCTTCGCGATAACGGCCC
TGAACTCTTTACCTCTAAGCATCAAGGTATCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References