Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 3097100..3098448 Replicon chromosome
Accession NZ_CP014207
Organism Pantoea ananatis strain R100

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag AW734_RS14465 Protein ID WP_064373812.1
Coordinates 3097100..3098209 (-) Length 370 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag AW734_RS14470 Protein ID WP_014605801.1
Coordinates 3098209..3098448 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AW734_RS14455 3094319..3096187 + 1869 WP_013025825.1 low affinity potassium transporter Kup -
AW734_RS14460 3096638..3097054 + 417 WP_014605803.1 GFA family protein -
AW734_RS14465 3097100..3098209 - 1110 WP_064373812.1 HipA domain-containing protein Toxin
AW734_RS14470 3098209..3098448 - 240 WP_014605801.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
AW734_RS14475 3098563..3099006 + 444 WP_015700266.1 GNAT family N-acetyltransferase -
AW734_RS14480 3099070..3101445 - 2376 WP_064373814.1 glycoside hydrolase family 3 C-terminal domain-containing protein -
AW734_RS14485 3101468..3102856 - 1389 WP_014605798.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(132-327)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-55)


Sequences

Toxin        


Download         Length: 370 a.a.        Molecular weight: 40905.24 Da        Isoelectric Point: 7.4551

>T60347 WP_064373812.1 NZ_CP014207:c3098209-3097100 [Pantoea ananatis]
MAKLIAWINGERTGTLTLHHNGALHFQYDANWLQHPLARPLSLSLPLQRAAMHSEKVVHFFENLLYPSTLIEKDFYPTHP
IKSCEVFAALQKVGHTLPGALSLLPAKRQPVAPDQATHSVFSPADEAQQFDIDNAYLCLSLARELTIPVPDAVLVHENGI
RKLRTERYDRRWRHDGQHLYHLPEEDVCQALGVPLSGRDEQQGGPGIDDIMALLMGSSSAMKDREDLMRCLVFQWLTGIT
RVNAKHLSLLIARGGSFRLAPFKHLLSACPGLSLRTTDRRDFQLGMGLTGPEGKQHHIDAIGPAHFLALAGSVGFSQAAM
RQILAAFIPGLPAAIIKVRDSLPDDYPLTLADAVFSHAMMMLERVRQAI

Download         Length: 1110 bp

>T60347 NZ_CP014207:c3098209-3097100 [Pantoea ananatis]
ATGGCAAAGCTCATTGCCTGGATAAACGGCGAGCGTACGGGAACGCTGACGCTGCATCACAACGGCGCGCTGCATTTCCA
GTATGACGCCAACTGGCTTCAGCATCCGCTTGCCAGACCTCTCTCGCTTTCGTTGCCCTTACAGCGCGCCGCGATGCATT
CTGAGAAAGTCGTGCACTTTTTCGAAAACCTTCTCTATCCCAGCACGTTGATCGAAAAGGATTTTTACCCGACTCACCCG
ATAAAATCCTGTGAGGTGTTTGCAGCATTGCAGAAAGTGGGACACACATTACCCGGGGCGCTCAGTCTGCTGCCGGCAAA
GCGGCAGCCCGTCGCGCCGGACCAGGCAACGCACAGCGTCTTCAGCCCCGCCGATGAGGCACAGCAGTTCGATATCGATA
ATGCGTATCTGTGTCTGTCCCTGGCCCGGGAGCTGACTATCCCGGTGCCGGATGCCGTGTTAGTTCATGAGAACGGCATC
CGTAAATTGAGAACAGAACGATACGATCGCCGTTGGCGTCACGACGGACAACACCTTTATCATCTTCCCGAAGAAGACGT
GTGTCAGGCGCTCGGCGTGCCGCTCTCTGGCCGCGATGAGCAGCAGGGCGGTCCGGGAATTGATGACATCATGGCCTTGC
TGATGGGCTCAAGCTCCGCCATGAAAGACCGTGAGGATCTGATGCGCTGTCTGGTATTTCAGTGGCTGACGGGCATCACA
CGCGTCAACGCTAAACATCTTTCGCTGCTGATTGCTCGCGGTGGCAGCTTCCGGCTCGCGCCTTTTAAGCATCTCCTTTC
CGCCTGCCCGGGCCTTTCTCTGCGCACAACAGACAGACGGGATTTCCAGCTGGGGATGGGCCTGACAGGCCCTGAGGGCA
AACAGCATCACATTGACGCGATTGGGCCCGCGCATTTTCTTGCCCTTGCGGGGAGCGTGGGGTTCAGTCAGGCAGCGATG
CGGCAGATACTGGCGGCCTTTATTCCGGGCTTGCCTGCCGCGATTATTAAGGTGCGGGACAGCCTGCCCGATGATTATCC
CCTGACGCTCGCCGATGCGGTTTTCAGCCACGCAATGATGATGCTGGAAAGGGTGCGCCAGGCGATCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8773.03 Da        Isoelectric Point: 7.2012

>AT60347 WP_014605801.1 NZ_CP014207:c3098448-3098209 [Pantoea ananatis]
MIYSPRQLANQVRLLRQQNGWTQVELAKKVGLKQATLSHFENAPDTTSLATLFKILQALDLALLLHENSASSAPAEDAW

Download         Length: 240 bp

>AT60347 NZ_CP014207:c3098448-3098209 [Pantoea ananatis]
ATGATTTACAGTCCCCGCCAGTTGGCAAATCAGGTCAGGCTACTGCGGCAGCAAAACGGCTGGACCCAGGTCGAACTGGC
GAAAAAAGTGGGCCTGAAACAGGCAACCCTGTCTCACTTCGAAAATGCCCCGGATACGACCTCACTGGCAACGTTGTTCA
AAATCTTACAGGCGCTCGATCTTGCTCTGTTGCTTCATGAAAACAGCGCATCCTCAGCCCCGGCTGAGGATGCCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References