Detailed information of TA system TA060345

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 6076359..6076839
• Replicon: chromosome
• Accession: NZ_CP014205
• Organism: Pseudomonas glycinae strain MS586

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AWU82_RS27795
• Protein ID: WP_080770598.1
• Coordinates: 6076555..6076839 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A4V6Q6W5
• Locus tag: AWU82_RS27790
• Protein ID: WP_034152589.1
• Coordinates: 6076359..6076565 (+)
• Length: 69 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AWU82_RS27775	6071843..6074077	+	2235	WP_064378918.1	cadherin-like domain-containing protein	-
AWU82_RS27780	6074148..6074612	+	465	WP_007956150.1	curlin	-
AWU82_RS27785	6074639..6076090	+	1452	WP_064378917.1	curlin	-
AWU82_RS27790	6076359..6076565	+	207	WP_034152589.1	hypothetical protein	Antitoxin
AWU82_RS27795	6076555..6076839	+	285	WP_080770598.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AWU82_RS27800	6077228..6077611	+	384	WP_064378915.1	hypothetical protein	-
AWU82_RS27805	6077763..6077954	-	192	WP_064378914.1	hypothetical protein	-
AWU82_RS27810	6078192..6078575	-	384	WP_064378913.1	hypothetical protein	-
AWU82_RS27815	6079362..6080222	-	861	WP_064378912.1	curli production assembly/transport protein CsgG	-
AWU82_RS27820	6080252..6080683	-	432	WP_007956141.1	curli production assembly protein CsgF	-
AWU82_RS27825	6080680..6081072	-	393	WP_064378911.1	curli production assembly/transport protein CsgE	-
AWU82_RS27830	6081069..6081608	-	540	WP_064378910.1	type II secretion system GspH family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10918.75 Da
• Isoelectric Point: 10.9931

>T60345 WP_080770598.1 NZ_CP014205:6076555-6076839 [Pseudomonas glycinae]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALPWHPHLYRKGRSPGTREIVVSPNYLVVYQVADRIEIVS
ILHARQEYPRRDPS

Nucleotide

• Length: 285 bp

>T60345 NZ_CP014205:6076555-6076839 [Pseudomonas glycinae]
ATGCAGATTAAGTGGCGACCCAAGGCTCGGGTCGAACTCTCGAAAATACTGAAGTACATTGGCGAGCGAAATTTTGTAGC
GGCGACAGCTCTTCATAAGTCAGTCGTAAAAACTACATCCGCGCTTCCTTGGCATCCACACCTGTATCGCAAAGGTCGCT
CTCCCGGCACTCGGGAGATTGTGGTAAGCCCGAACTATCTCGTCGTCTATCAAGTGGCGGACCGAATTGAGATTGTGAGC
ATCTTGCATGCGCGTCAGGAATACCCTCGACGCGACCCCAGTTAG

Antitoxin

Protein

• Length: 69 a.a.
• Molecular weight: 7672.54 Da
• Isoelectric Point: 3.8068

>AT60345 WP_034152589.1 NZ_CP014205:6076359-6076565 [Pseudomonas glycinae]
MIDPSLIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMEEINALMESMRKSADAD

Nucleotide

• Length: 207 bp

>AT60345 NZ_CP014205:6076359-6076565 [Pseudomonas glycinae]
ATGATCGACCCGTCTTTGATCGACCCACTGTGCCCGGTTGTTTCGGATCTTGATCCTGAGGAACAGGCTGCGAGTTATGA
CCGTTGGTTTCGGGCCGAAGTACAGGCCTCTCTCGATGATCCGCGTCCGAGTATTCCCCATGAGCAAGTGATGGAGGAAA
TAAACGCCTTGATGGAATCAATGCGCAAAAGCGCTGATGCAGATTAA

Structures

Antitoxin

• AlphaFold DB: A0A4V6Q6W5