Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PsyrTA/- |
| Location | 4522205..4525665 | Replicon | chromosome |
| Accession | NC_007005 | ||
| Organism | Pseudomonas syringae pv. syringae B728a | ||
Toxin (Protein)
| Gene name | PsyrT | Uniprot ID | Q4ZPT7 |
| Locus tag | PSYR_RS19685 | Protein ID | WP_011268660.1 |
| Coordinates | 4522205..4524301 (+) | Length | 699 a.a. |
Antitoxin (Protein)
| Gene name | PsyrA | Uniprot ID | Q4ZPT6 |
| Locus tag | PSYR_RS19690 | Protein ID | WP_011268661.1 |
| Coordinates | 4524298..4525665 (+) | Length | 456 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PSYR_RS19670 (Psyr_3801) | 4518247..4519140 | + | 894 | WP_003425485.1 | LysR family transcriptional regulator | - |
| PSYR_RS19675 (Psyr_3802) | 4519156..4520268 | - | 1113 | WP_011268658.1 | hypothetical protein | - |
| PSYR_RS19680 (Psyr_3803) | 4520428..4521720 | + | 1293 | WP_011268659.1 | mechanosensitive ion channel family protein | - |
| PSYR_RS19685 (Psyr_3804) | 4522205..4524301 | + | 2097 | WP_011268660.1 | RecQ family ATP-dependent DNA helicase | Toxin |
| PSYR_RS19690 (Psyr_3805) | 4524298..4525665 | + | 1368 | WP_011268661.1 | DNA-protecting protein DprA | Antitoxin |
| PSYR_RS19695 (Psyr_3806) | 4526367..4526816 | + | 450 | WP_164920506.1 | hypothetical protein | - |
| PSYR_RS19700 | 4527028..4527558 | - | 531 | Protein_3829 | transposase | - |
| PSYR_RS19705 (Psyr_3807) | 4527902..4529116 | + | 1215 | WP_011268663.1 | hypothetical protein | - |
| PSYR_RS19710 (Psyr_3808) | 4529113..4529592 | + | 480 | WP_011268664.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4522205..4542585 | 20380 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 699 a.a. Molecular weight: 77936.02 Da Isoelectric Point: 7.3210
>T6032 WP_011268660.1 NC_007005:4522205-4524301 [Pseudomonas syringae pv. syringae B728a]
MQRNDAEKLLKVAINNGAATFRDGQWEAIDALVNHRKKLLVVQRTGWGKSSVYFISTRILRDRGQGPTIIISPLLALMRN
QVDAAQRLGINAVTINSTNTDEWEKARQDVHANRVDCLLISPERLANDGFMETFLQPIADRIGLMVIDEAHCISDWGHDF
RPDYRRIVNILRFLPPNTPVLGTTATANTRVVNDIQAQFGDINIVRGPLARESLALQNLIMPDQASRLAWLAQTIPTLPG
TGIVYALTQRDSEQVARWLRANGIDAASYHSDVAHSDFGNSDQYRQHLEDELLANKLKVLVATTALGMGYDKPDLGFVIH
YQAPSSLVAYYQQVGRAGRAIDYSLGLLMSGEEDEKIHAFFRRAAFPPAGQVNHLLSVLAKSNGLTIRELEEHSNLSHGQ
IEKILKLLSVESPAPLIKHQSKWLRTPIHYELDQNRVSRLTELREHEWQQVLAYLNEPRCLMAFLRHALDDAENDACGKC
VRCLERELVSSKVDGRLVHQAATFIRHAELPIKPKKQIAKGGFEYYGFPTNLPLNIQAAEGRVLSQWRDGSWGELAANGK
ELGHFDDALVSAMAEMIQSRWQPNPKPTWLCCVPSLGHPMLVPDFAQRLANALGIPFVNCVTKVRQNEPQKWQNNRFHQC
RNLDGVFAVSAHIPPGPVLLVDDMIDSGWTMTVIAALLKQAGSEHVYPLAISSTASNA
MQRNDAEKLLKVAINNGAATFRDGQWEAIDALVNHRKKLLVVQRTGWGKSSVYFISTRILRDRGQGPTIIISPLLALMRN
QVDAAQRLGINAVTINSTNTDEWEKARQDVHANRVDCLLISPERLANDGFMETFLQPIADRIGLMVIDEAHCISDWGHDF
RPDYRRIVNILRFLPPNTPVLGTTATANTRVVNDIQAQFGDINIVRGPLARESLALQNLIMPDQASRLAWLAQTIPTLPG
TGIVYALTQRDSEQVARWLRANGIDAASYHSDVAHSDFGNSDQYRQHLEDELLANKLKVLVATTALGMGYDKPDLGFVIH
YQAPSSLVAYYQQVGRAGRAIDYSLGLLMSGEEDEKIHAFFRRAAFPPAGQVNHLLSVLAKSNGLTIRELEEHSNLSHGQ
IEKILKLLSVESPAPLIKHQSKWLRTPIHYELDQNRVSRLTELREHEWQQVLAYLNEPRCLMAFLRHALDDAENDACGKC
VRCLERELVSSKVDGRLVHQAATFIRHAELPIKPKKQIAKGGFEYYGFPTNLPLNIQAAEGRVLSQWRDGSWGELAANGK
ELGHFDDALVSAMAEMIQSRWQPNPKPTWLCCVPSLGHPMLVPDFAQRLANALGIPFVNCVTKVRQNEPQKWQNNRFHQC
RNLDGVFAVSAHIPPGPVLLVDDMIDSGWTMTVIAALLKQAGSEHVYPLAISSTASNA
Download Length: 2097 bp
>T6032 NC_007005:4522205-4524301 [Pseudomonas syringae pv. syringae B728a]
ATGCAACGGAACGATGCAGAGAAACTACTGAAAGTCGCCATCAACAACGGAGCCGCTACGTTTAGGGATGGGCAATGGGA
GGCGATTGATGCTCTGGTCAACCATCGCAAGAAACTGTTAGTCGTTCAACGCACTGGTTGGGGCAAGAGCTCTGTTTACT
TTATCAGCACGCGAATTCTGCGTGATCGAGGGCAAGGCCCAACCATAATCATATCGCCCCTACTAGCCCTGATGCGCAAT
CAGGTCGACGCAGCTCAGCGACTAGGGATCAATGCCGTTACCATTAACTCTACCAATACTGACGAATGGGAAAAGGCCCG
TCAGGATGTGCACGCCAACCGAGTAGATTGCTTGTTGATCTCACCAGAGCGGCTAGCAAATGACGGCTTCATGGAAACCT
TTCTGCAGCCCATCGCAGATCGCATCGGCTTGATGGTAATAGATGAGGCGCACTGCATTTCCGACTGGGGGCATGATTTC
CGGCCCGATTATCGCCGTATCGTCAACATTCTGCGCTTCCTTCCCCCCAACACACCCGTTTTGGGTACGACTGCGACTGC
AAATACTCGGGTGGTGAACGATATTCAGGCTCAGTTTGGAGATATAAACATCGTCCGTGGCCCTCTGGCCCGAGAAAGTT
TGGCGTTACAAAATTTGATCATGCCCGATCAAGCCAGCCGTCTGGCATGGCTGGCGCAGACCATTCCAACCTTACCTGGG
ACGGGCATCGTTTATGCGCTCACCCAGCGCGATAGTGAGCAGGTCGCCCGCTGGCTTCGCGCTAACGGAATCGATGCTGC
TTCCTATCACAGTGATGTCGCCCACTCTGACTTTGGCAATAGCGATCAATATCGCCAACATCTAGAAGATGAACTGCTGG
CAAACAAGCTCAAGGTGCTCGTCGCGACCACTGCGTTAGGTATGGGCTATGACAAGCCCGACCTTGGCTTCGTCATTCAC
TATCAAGCGCCTAGCTCGCTTGTTGCCTACTACCAGCAGGTCGGTCGGGCAGGACGGGCAATCGATTACTCACTCGGCTT
GCTCATGTCTGGGGAAGAGGACGAGAAAATTCATGCGTTTTTTAGACGCGCAGCTTTTCCTCCCGCAGGGCAGGTCAATC
ATTTGCTGAGTGTCCTAGCGAAATCCAATGGGCTGACGATTCGTGAACTAGAAGAGCACAGCAACCTCTCACATGGGCAG
ATTGAGAAAATTCTCAAGCTCCTGAGCGTGGAAAGCCCAGCGCCACTCATCAAGCACCAAAGCAAATGGCTACGCACCCC
AATCCATTACGAGCTGGATCAGAATCGTGTTAGCAGGCTTACCGAGCTACGAGAGCATGAATGGCAGCAGGTTCTGGCAT
ACTTGAATGAACCAAGGTGCCTTATGGCGTTCCTACGACATGCATTGGATGACGCGGAGAATGATGCTTGCGGGAAATGC
GTGCGCTGCCTAGAGAGGGAGTTGGTATCAAGTAAAGTAGACGGTAGATTGGTGCATCAAGCCGCTACCTTTATTCGCCA
TGCCGAGCTTCCAATCAAGCCCAAGAAGCAAATCGCCAAGGGAGGCTTTGAGTATTACGGCTTCCCGACCAACCTCCCTC
TCAACATACAGGCGGCTGAAGGTAGAGTCCTTTCACAATGGCGTGATGGAAGCTGGGGAGAATTAGCTGCCAACGGCAAG
GAGCTCGGCCATTTTGACGATGCTCTGGTTTCAGCCATGGCAGAAATGATCCAATCGCGCTGGCAACCGAATCCTAAACC
CACGTGGTTGTGCTGCGTGCCTTCTCTAGGGCATCCAATGTTAGTACCTGACTTTGCTCAGCGCTTGGCGAATGCATTGG
GGATCCCCTTCGTCAACTGTGTGACCAAGGTAAGGCAAAACGAGCCGCAAAAGTGGCAAAACAATCGCTTCCACCAGTGT
CGGAATCTAGATGGTGTGTTCGCCGTTAGTGCACATATTCCTCCTGGCCCGGTGCTGCTGGTTGATGACATGATCGATTC
AGGCTGGACAATGACCGTCATTGCCGCACTGCTCAAACAAGCGGGCAGCGAACACGTCTACCCGCTGGCAATCTCATCTA
CGGCAAGCAACGCATGA
ATGCAACGGAACGATGCAGAGAAACTACTGAAAGTCGCCATCAACAACGGAGCCGCTACGTTTAGGGATGGGCAATGGGA
GGCGATTGATGCTCTGGTCAACCATCGCAAGAAACTGTTAGTCGTTCAACGCACTGGTTGGGGCAAGAGCTCTGTTTACT
TTATCAGCACGCGAATTCTGCGTGATCGAGGGCAAGGCCCAACCATAATCATATCGCCCCTACTAGCCCTGATGCGCAAT
CAGGTCGACGCAGCTCAGCGACTAGGGATCAATGCCGTTACCATTAACTCTACCAATACTGACGAATGGGAAAAGGCCCG
TCAGGATGTGCACGCCAACCGAGTAGATTGCTTGTTGATCTCACCAGAGCGGCTAGCAAATGACGGCTTCATGGAAACCT
TTCTGCAGCCCATCGCAGATCGCATCGGCTTGATGGTAATAGATGAGGCGCACTGCATTTCCGACTGGGGGCATGATTTC
CGGCCCGATTATCGCCGTATCGTCAACATTCTGCGCTTCCTTCCCCCCAACACACCCGTTTTGGGTACGACTGCGACTGC
AAATACTCGGGTGGTGAACGATATTCAGGCTCAGTTTGGAGATATAAACATCGTCCGTGGCCCTCTGGCCCGAGAAAGTT
TGGCGTTACAAAATTTGATCATGCCCGATCAAGCCAGCCGTCTGGCATGGCTGGCGCAGACCATTCCAACCTTACCTGGG
ACGGGCATCGTTTATGCGCTCACCCAGCGCGATAGTGAGCAGGTCGCCCGCTGGCTTCGCGCTAACGGAATCGATGCTGC
TTCCTATCACAGTGATGTCGCCCACTCTGACTTTGGCAATAGCGATCAATATCGCCAACATCTAGAAGATGAACTGCTGG
CAAACAAGCTCAAGGTGCTCGTCGCGACCACTGCGTTAGGTATGGGCTATGACAAGCCCGACCTTGGCTTCGTCATTCAC
TATCAAGCGCCTAGCTCGCTTGTTGCCTACTACCAGCAGGTCGGTCGGGCAGGACGGGCAATCGATTACTCACTCGGCTT
GCTCATGTCTGGGGAAGAGGACGAGAAAATTCATGCGTTTTTTAGACGCGCAGCTTTTCCTCCCGCAGGGCAGGTCAATC
ATTTGCTGAGTGTCCTAGCGAAATCCAATGGGCTGACGATTCGTGAACTAGAAGAGCACAGCAACCTCTCACATGGGCAG
ATTGAGAAAATTCTCAAGCTCCTGAGCGTGGAAAGCCCAGCGCCACTCATCAAGCACCAAAGCAAATGGCTACGCACCCC
AATCCATTACGAGCTGGATCAGAATCGTGTTAGCAGGCTTACCGAGCTACGAGAGCATGAATGGCAGCAGGTTCTGGCAT
ACTTGAATGAACCAAGGTGCCTTATGGCGTTCCTACGACATGCATTGGATGACGCGGAGAATGATGCTTGCGGGAAATGC
GTGCGCTGCCTAGAGAGGGAGTTGGTATCAAGTAAAGTAGACGGTAGATTGGTGCATCAAGCCGCTACCTTTATTCGCCA
TGCCGAGCTTCCAATCAAGCCCAAGAAGCAAATCGCCAAGGGAGGCTTTGAGTATTACGGCTTCCCGACCAACCTCCCTC
TCAACATACAGGCGGCTGAAGGTAGAGTCCTTTCACAATGGCGTGATGGAAGCTGGGGAGAATTAGCTGCCAACGGCAAG
GAGCTCGGCCATTTTGACGATGCTCTGGTTTCAGCCATGGCAGAAATGATCCAATCGCGCTGGCAACCGAATCCTAAACC
CACGTGGTTGTGCTGCGTGCCTTCTCTAGGGCATCCAATGTTAGTACCTGACTTTGCTCAGCGCTTGGCGAATGCATTGG
GGATCCCCTTCGTCAACTGTGTGACCAAGGTAAGGCAAAACGAGCCGCAAAAGTGGCAAAACAATCGCTTCCACCAGTGT
CGGAATCTAGATGGTGTGTTCGCCGTTAGTGCACATATTCCTCCTGGCCCGGTGCTGCTGGTTGATGACATGATCGATTC
AGGCTGGACAATGACCGTCATTGCCGCACTGCTCAAACAAGCGGGCAGCGAACACGTCTACCCGCTGGCAATCTCATCTA
CGGCAAGCAACGCATGA
Antitoxin
Download Length: 456 a.a. Molecular weight: 49510.88 Da Isoelectric Point: 6.8375
>AT6032 WP_011268661.1 NC_007005:4524298-4525665 [Pseudomonas syringae pv. syringae B728a]
MINTNTQSILLLTSYFSKSVGGAKPLSPTEWGRFAQWLNAQGKTPADLVTAEPHAVLEGWHDEKIPLLRIEQLLERGHAL
ALALEKWSRAGLWVLTRSDADYPKALKHHLRNSAPPILFGCGNPRLLNQRGIGVVGARKADDADLAYATSLGKRIAMAGM
TVVSGGARGVDEAAMQGGLNEEGTVIGIMADSLLSAALASKWRNGLMSNNLVLVSPFFPEAGFNAGNAMARNKYIYCLSQ
AAVVVRSETRGGTWNGAIENLKKAWVPLWVKRDTNPESGNYALVSQGAQWLESAAKHVDVHTLSAQAKPESDPEMVPELA
PTDQDASISEEDPVRSPPPRDEAPHQLSRDDGRSSQNANSASTHATTIGDLSFYQFFLRKMALRDSPGTAEELSEQWGIS
KKQLTEWLKQSVDERHVQKLKNPVRFQSLDVGKFEGSIGKNLDPSSDGQLGFKLD
MINTNTQSILLLTSYFSKSVGGAKPLSPTEWGRFAQWLNAQGKTPADLVTAEPHAVLEGWHDEKIPLLRIEQLLERGHAL
ALALEKWSRAGLWVLTRSDADYPKALKHHLRNSAPPILFGCGNPRLLNQRGIGVVGARKADDADLAYATSLGKRIAMAGM
TVVSGGARGVDEAAMQGGLNEEGTVIGIMADSLLSAALASKWRNGLMSNNLVLVSPFFPEAGFNAGNAMARNKYIYCLSQ
AAVVVRSETRGGTWNGAIENLKKAWVPLWVKRDTNPESGNYALVSQGAQWLESAAKHVDVHTLSAQAKPESDPEMVPELA
PTDQDASISEEDPVRSPPPRDEAPHQLSRDDGRSSQNANSASTHATTIGDLSFYQFFLRKMALRDSPGTAEELSEQWGIS
KKQLTEWLKQSVDERHVQKLKNPVRFQSLDVGKFEGSIGKNLDPSSDGQLGFKLD
Download Length: 1368 bp
>AT6032 NC_007005:4524298-4525665 [Pseudomonas syringae pv. syringae B728a]
ATGATAAATACCAATACTCAGTCGATCCTCCTACTAACGTCTTATTTTTCAAAATCTGTAGGTGGTGCCAAACCGCTATC
TCCGACGGAATGGGGACGATTTGCCCAATGGCTAAACGCGCAGGGCAAGACGCCTGCAGACTTAGTGACTGCTGAGCCAC
ATGCTGTGCTTGAGGGCTGGCATGATGAAAAAATACCATTGCTGCGCATTGAGCAGTTGCTCGAGCGAGGCCATGCGCTG
GCCTTGGCTTTGGAGAAGTGGAGCCGGGCTGGATTGTGGGTGCTGACACGATCAGATGCTGACTATCCTAAGGCGCTCAA
GCATCACTTACGTAACAGCGCGCCACCGATACTCTTCGGTTGTGGAAATCCGCGACTGCTGAATCAACGTGGAATTGGTG
TTGTCGGCGCACGTAAGGCGGATGATGCCGACCTTGCATACGCCACGTCTTTAGGTAAACGCATCGCGATGGCCGGCATG
ACCGTAGTCTCGGGTGGCGCTCGGGGCGTCGATGAAGCTGCGATGCAGGGCGGATTGAACGAAGAAGGAACTGTAATTGG
CATTATGGCTGATAGCCTTTTGTCGGCAGCGCTAGCCAGCAAATGGCGGAATGGGTTGATGAGCAACAACCTGGTACTGG
TTTCACCATTTTTTCCCGAGGCCGGATTCAACGCCGGCAATGCAATGGCTAGGAACAAATACATTTACTGCCTGAGTCAG
GCTGCAGTGGTCGTTCGCTCCGAAACCAGAGGCGGAACCTGGAACGGTGCCATCGAAAACTTGAAAAAAGCTTGGGTGCC
CCTGTGGGTTAAGCGAGATACGAACCCGGAATCCGGAAATTACGCGTTGGTATCACAAGGTGCGCAATGGCTGGAATCAG
CAGCGAAGCATGTGGATGTGCATACGCTGAGTGCCCAAGCTAAGCCAGAGTCTGACCCAGAGATGGTGCCGGAGTTAGCA
CCAACTGACCAAGATGCTTCTATCTCTGAAGAAGACCCCGTCAGATCGCCCCCCCCCCGAGACGAGGCGCCACACCAACT
TTCCCGAGATGATGGTAGGAGTAGTCAGAATGCTAATTCTGCTTCGACTCACGCCACAACTATTGGCGACCTGAGTTTTT
ATCAATTTTTTCTAAGGAAGATGGCACTCCGGGATAGTCCAGGAACCGCTGAGGAGCTAAGCGAGCAATGGGGTATCTCA
AAGAAACAGCTCACTGAATGGCTCAAGCAGTCAGTCGATGAAAGACACGTTCAAAAGCTGAAAAACCCTGTTCGCTTCCA
GTCGTTGGATGTCGGAAAATTCGAGGGCAGCATCGGGAAGAACTTAGACCCTTCATCCGATGGGCAACTGGGGTTCAAGC
TGGATTGA
ATGATAAATACCAATACTCAGTCGATCCTCCTACTAACGTCTTATTTTTCAAAATCTGTAGGTGGTGCCAAACCGCTATC
TCCGACGGAATGGGGACGATTTGCCCAATGGCTAAACGCGCAGGGCAAGACGCCTGCAGACTTAGTGACTGCTGAGCCAC
ATGCTGTGCTTGAGGGCTGGCATGATGAAAAAATACCATTGCTGCGCATTGAGCAGTTGCTCGAGCGAGGCCATGCGCTG
GCCTTGGCTTTGGAGAAGTGGAGCCGGGCTGGATTGTGGGTGCTGACACGATCAGATGCTGACTATCCTAAGGCGCTCAA
GCATCACTTACGTAACAGCGCGCCACCGATACTCTTCGGTTGTGGAAATCCGCGACTGCTGAATCAACGTGGAATTGGTG
TTGTCGGCGCACGTAAGGCGGATGATGCCGACCTTGCATACGCCACGTCTTTAGGTAAACGCATCGCGATGGCCGGCATG
ACCGTAGTCTCGGGTGGCGCTCGGGGCGTCGATGAAGCTGCGATGCAGGGCGGATTGAACGAAGAAGGAACTGTAATTGG
CATTATGGCTGATAGCCTTTTGTCGGCAGCGCTAGCCAGCAAATGGCGGAATGGGTTGATGAGCAACAACCTGGTACTGG
TTTCACCATTTTTTCCCGAGGCCGGATTCAACGCCGGCAATGCAATGGCTAGGAACAAATACATTTACTGCCTGAGTCAG
GCTGCAGTGGTCGTTCGCTCCGAAACCAGAGGCGGAACCTGGAACGGTGCCATCGAAAACTTGAAAAAAGCTTGGGTGCC
CCTGTGGGTTAAGCGAGATACGAACCCGGAATCCGGAAATTACGCGTTGGTATCACAAGGTGCGCAATGGCTGGAATCAG
CAGCGAAGCATGTGGATGTGCATACGCTGAGTGCCCAAGCTAAGCCAGAGTCTGACCCAGAGATGGTGCCGGAGTTAGCA
CCAACTGACCAAGATGCTTCTATCTCTGAAGAAGACCCCGTCAGATCGCCCCCCCCCCGAGACGAGGCGCCACACCAACT
TTCCCGAGATGATGGTAGGAGTAGTCAGAATGCTAATTCTGCTTCGACTCACGCCACAACTATTGGCGACCTGAGTTTTT
ATCAATTTTTTCTAAGGAAGATGGCACTCCGGGATAGTCCAGGAACCGCTGAGGAGCTAAGCGAGCAATGGGGTATCTCA
AAGAAACAGCTCACTGAATGGCTCAAGCAGTCAGTCGATGAAAGACACGTTCAAAAGCTGAAAAACCCTGTTCGCTTCCA
GTCGTTGGATGTCGGAAAATTCGAGGGCAGCATCGGGAAGAACTTAGACCCTTCATCCGATGGGCAACTGGGGTTCAAGC
TGGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
References
(1) Hila Sberro et al. (2013) Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning. Molecular Cell 50(1):136-48. [PubMed:23478446]