Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 589757..590307 Replicon chromosome
Accession NZ_CP014159
Organism Aerococcus christensenii strain CCUG28831

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AWM71_RS02810 Protein ID WP_060776564.1
Coordinates 589757..590038 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AWM71_RS02815 Protein ID WP_060776565.1
Coordinates 590035..590307 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWM71_RS02785 584889..585779 - 891 WP_060776562.1 GIY-YIG nuclease family protein -
AWM71_RS02790 586113..586525 - 413 Protein_522 hypothetical protein -
AWM71_RS07865 586557..586754 - 198 WP_076003161.1 helix-turn-helix transcriptional regulator -
AWM71_RS02795 586842..587958 - 1117 Protein_524 MobA/MobL family protein -
AWM71_RS02800 588599..588898 + 300 WP_006731133.1 hypothetical protein -
AWM71_RS02805 588992..589468 - 477 WP_201783963.1 hypothetical protein -
AWM71_RS02810 589757..590038 - 282 WP_060776564.1 type II toxin-antitoxin system YafQ family toxin Toxin
AWM71_RS02815 590035..590307 - 273 WP_060776565.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AWM71_RS02820 591197..592102 - 906 WP_060776566.1 3'-5' exonuclease -
AWM71_RS02825 592292..592849 - 558 WP_004111734.1 TetR/AcrR family transcriptional regulator -
AWM71_RS02830 592979..593500 + 522 WP_004111736.1 HXXEE domain-containing protein -
AWM71_RS02835 593539..594720 + 1182 WP_060776567.1 alpha/beta fold hydrolase -
AWM71_RS02840 594848..595111 - 264 WP_060776568.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10736.47 Da        Isoelectric Point: 9.3596

>T60313 WP_060776564.1 NZ_CP014159:c590038-589757 [Aerococcus christensenii]
MKYEVKFTNQFKKNLKLAKKQNKNTDSLLKVIDVLADGGVLEAKYCDHGLSGKYSGTRECHNEPDWLLVYEIKNEVLGLM
LYRLGTHSELFKK

Download         Length: 282 bp

>T60313 NZ_CP014159:c590038-589757 [Aerococcus christensenii]
ATGAAATATGAAGTAAAATTCACGAACCAGTTCAAAAAAAACCTTAAATTAGCTAAGAAACAAAATAAAAATACGGATAG
TCTTTTAAAAGTAATTGATGTTTTAGCTGACGGTGGTGTGCTAGAAGCTAAATATTGTGATCACGGTCTGTCTGGAAAAT
ATAGCGGAACAAGAGAATGTCATAATGAACCGGATTGGCTTTTAGTTTATGAAATTAAGAATGAAGTTCTTGGTTTGATG
TTATATAGGCTGGGTACACATTCAGAATTGTTTAAGAAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10074.53 Da        Isoelectric Point: 4.8146

>AT60313 WP_060776565.1 NZ_CP014159:c590307-590035 [Aerococcus christensenii]
MATTNLNIRTDKEIKEQADKIFSELGLNMTTAINMFLRTTIRENGIPFSLKLETPTDTTIAAIEEGRRIASDPSVKGYRN
MEDIKAALDL

Download         Length: 273 bp

>AT60313 NZ_CP014159:c590307-590035 [Aerococcus christensenii]
ATGGCTACTACGAATTTAAATATCAGAACAGATAAGGAAATTAAAGAACAAGCTGATAAGATTTTCTCAGAACTCGGGCT
TAATATGACGACAGCGATTAACATGTTTTTGCGAACAACTATTCGTGAGAACGGGATTCCTTTTTCTCTTAAATTAGAGA
CTCCGACTGATACAACGATTGCTGCTATTGAGGAAGGTAGACGGATTGCGTCTGATCCTAGTGTAAAGGGTTATCGAAAT
ATGGAAGATATTAAGGCAGCTCTTGATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References